fomivirsen

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/03/06 19:34:51」(JST)

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英文文献

  • Intravitreal clearance and volume of distribution of compounds in rabbits: In silico prediction and pharmacokinetic simulations for drug development.
  • del Amo EM1, Vellonen KS2, Kidron H3, Urtti A4.
  • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.Eur J Pharm Biopharm.2015 Sep;95(Pt B):215-26. doi: 10.1016/j.ejpb.2015.01.003. Epub 2015 Jan 17.
  • The aims of this research were to (1) create a curated universal database of intravitreal volumes of distribution (Vss, ivt) and clearances (CL ivt) of small molecular weight compounds and macromolecules and (2) to develop quantitative structure property relationship (QSPR) and pharmacokinetic model
  • PMID 25603198
  • Therapeutic antisense oligonucleotides against cancer: hurdling to the clinic.
  • Moreno PM1, Pêgo AP2.
  • Frontiers in chemistry.Front Chem.2014 Oct 14;2:87. doi: 10.3389/fchem.2014.00087. eCollection 2014.
  • Under clinical development since the early 90's and with two successfully approved drugs (Fomivirsen and Mipomersen), oligonucleotide-based therapeutics has not yet delivered a clinical drug to the market in the cancer field. Whilst many pre-clinical data has been generated, a lack of understanding
  • PMID 25353019
  • Relieving bottlenecks in RNA drug discovery for retinal diseases.
  • Sullivan JM1, Yau EH, Taggart RT, Butler MC, Kolniak TA.
  • Advances in experimental medicine and biology.Adv Exp Med Biol.2012;723:145-53. doi: 10.1007/978-1-4614-0631-0_20.
  • PMID 22183327

和文文献

  • サイトメガロウイルス感染症 (特集 呼吸器ウイルス感染症 update)
  • Fomivirsen
  • Fomivirsen : a phosphorothioate oligonucleotide for the treatment of CMV retinitis

関連リンク

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Vitravene (Fomivirsen) Drug Information  FOMIVIRSEN-Rx of CMV retinitis #USMLE # Fomivirsen, CAS No 144245-52-3 FomivirsenFomivirsen - Wikipedia, the free  › Medications › Fomivirsen sodiumDrugs reference index « Vitravene »


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