関: Heck's disease

WordNet

of or relating to a focus; "focal length"
having or localized centrally at a focus; "focal point"; "focal infection"
of or belonging to the epithelium; "epithelial layer"
abnormal increase in number of cells

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/12/25 10:14:29」(JST)

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Heck's disease (also known as focal epithelial hyperplasia) is a cutaneous condition characterized by white to pinkish papules that occur diffusely in the oral cavity.^[1]^:411 It is caused by the human papilloma virus types 13 and 32. It exhibits surface cells with vacuolated cytoplasm around irregular, pyknotic nuclei and occasional cells with mitosis-like changes within otherwise mature and well-differentiated epithelium.

References[edit]

^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.

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English Journal

Thymic lymphoid hyperplasia with multilocular thymic cysts diagnosed before the Sjögren syndrome diagnosis.

Minato H1, Kinoshita E2, Nakada S3, Nojima T4, Tanaka M5, Usuda K6, Sagawa M7, Iwao H8, Tanaka M9, Doai M10, Takahashi T11, Shibata N12.
Diagnostic pathology.Diagn Pathol.2015 Jul 16;10(1):103. doi: 10.1186/s13000-015-0332-y.
BACKGROUND: Thymic lymphoid hyperplasia is often present with myasthenia gravis as well as other autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. Of the 4 cases of thymic lymphoid hyperplasia associated with Sjögren syndrome that have been reported, no case with a
PMID 26173602

Histopathological changes in gill and liver of Capoeta capoeta living in the Karasu River, Erzurum.

Dane H1, Şişman T1.
Environmental toxicology.Environ Toxicol.2015 Jul 8;30(8):904-17. doi: 10.1002/tox.21965. Epub 2014 Feb 10.
The contamination of surface waters by different pollutants is an important problem worldwide. In this study, the histopathological effects of water pollution were investigated on freshwater fish species Capoeta capoeta caught from the Karasu River. Fish were caught at three different sites in the K
PMID 24510427

Focal epithelial hyperplasia by human papillomavirus (HPV)-32 misdiagnosed as HPV-16 and treated with combination of retinoids, imiquimod and quadrivalent HPV vaccine.

Gemigniani F1, Hernández-Losa J2, Ferrer B2, García-Patos V1.
The Journal of dermatology.J Dermatol.2015 Jun 5. doi: 10.1111/1346-8138.12967. [Epub ahead of print]
Focal epithelial hyperplasia (FEH) or Heck's disease is a rare, benign and asymptomatic mucosal proliferation associated with human papillomavirus (HPV) infection, mainly with genotypes 13 and 32. We report a florid case of FEH in an 11-year-old Haitian girl with systemic lupus erythematosus receivi
PMID 26047065

Japanese Journal

海綿状血管腫，限局性結節性過形成が合併した肝類上皮性血管内皮腫の1切除例

水上達三,神山俊哉,中西一彰,横尾英樹,田原宗徳,福森大介,蒲池浩文,松下通明,藤堂省
日本消化器外科学会雑誌 44(2), 131-137, 2011
　症例は44歳の女性で，生来著患はないが，経口避妊薬の内服歴があった．2008年10月，健診にて肝機能異常を指摘され，腹部エコーを施行したところ，肝両葉に最大径が38mmで低～高エコーの多発する腫瘍を指摘された．CTでは肝両葉の辺縁を中心に，多発性の腫瘤性病変を認めるも確定診断に至らなかった．腹腔鏡下肝生検を施行し，肝類上皮性血管内皮腫（以下，H-EHEと略記）の診断となり移植を含めた加療目的に当 …
NAID 130004907997

十二指腸乳頭部Ｐａｐｉｌｌａｒｙ　ｈｙｐｅｒｐｌａｓｉａの１例

浜田義浩,眞栄城兼清,中山吉福,佐々木隆光,福地聡士
胆道 25(4), 688-693, 2011
… 得られなかったが，非露出型の乳頭部癌を否定出来ず，PPPDが施行された．術中，拡張した胆管を切離する際に，暗緑色の胆汁が噴出した．固定後の標本で主乳頭の割面をみると，乳頭部胆管領域に，内腔面に向かって発育する乳頭状の増殖性病変を認めた．同病変は異型に乏しい一層の円柱上皮細胞で覆われており，間質には軽度の慢性活動性炎症細胞浸潤を伴っていた．上記所見からpapillary hyperplasiaと考えられた． …
NAID 130004545412

胆嚢発癌におけるErbB2蛋白発現:ErbB2トランスジェニックマウス胆嚢癌を用いた検討

川本徹,RUFFINO Lynnsie,味木徹夫,DIGIOVANNI John,木口薫
胆道 19(5), 550-556, 2005
… 52例の内訳は, 正常4例, 過形成上皮14例, 癌が34例で, 全体の65%に癌発生が認められた.癌組織発生過程は, ポリープ状に生じた過形成上皮 (hyperplasia in focal lesion;HIF) から癌が発生したと考えられる癌 (HIF型癌) と, 粘膜全体に一様に認められる過形成上皮 (hyperplasia in whole epithelium(HIW)) から発生したと考えられる癌 (HIW型癌) の2型に分類できた. …
NAID 130004675777