WordNet

a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

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Nobre LT, Vidal AA, Almeida-Lima J, Oliveira RM, Paredes-Gamero EJ, Medeiros VP, Trindade ES, Franco CR, Nader HB, Rocha HA.SourceDepartamento de Bioquímica, Universidade Federal do Rio Grande do Norte - UFRN, Av. Senador Salgado Filho, 3000, Lagoa Nova, 59072-970 Natal, RN, Brazil; Disciplina de Biologia Molecular, Depto. de Bioquímica, Universidade Federal de São Paulo - UNIFESP, Rua Tres de maio, 100, 4° andar, Vila Clementino, São Paulo, SP, Brazil.
Carbohydrate polymers.Carbohydr Polym.2013 Oct 15;98(1):224-32. doi: 10.1016/j.carbpol.2013.05.040. Epub 2013 May 25.
Fucan is a term used to denominate sulfated l-fucose rich polysaccharides. Here, a heterofucan, named fucan B, was extracted from the Spatoglossum schröederi seaweed. This 21.5kDa galactofucan inhibited CHO-K1 proliferation and migration when fibronectin was the substrate. Fucan B derivatives revea
PMID 23987339

Protein tyrosine phosphatase variants in human hereditary disorders and disease susceptibilities.

Hendriks WJ, Pulido R.SourceDepartment of Cell Biology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. w.hendriks@ncmls.ru.nl
Biochimica et biophysica acta.Biochim Biophys Acta.2013 Oct;1832(10):1673-96. doi: 10.1016/j.bbadis.2013.05.022. Epub 2013 May 23.
Reversible tyrosine phosphorylation of proteins is a key regulatory mechanism to steer normal development and physiological functioning of multicellular organisms. Phosphotyrosine dephosphorylation is exerted by members of the super-family of protein tyrosine phosphatase (PTP) enzymes and many play
PMID 23707412

Fan X, Tang L.SourceKey Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China.
Gene.Gene.2013 Oct 1;528(1):21-6. doi: 10.1016/j.gene.2013.06.027. Epub 2013 Jun 23.
The main function of skeletal system is to support the body and help movement. A variety of factors can lead to skeletal system disease, including age, exercise, and of course genetic makeup and expression. Pre-mRNA splicing plays a crucial role in gene expression, by creating multiple protein varia
PMID 23800666

ONO-1301, a Sustained-Release Prostacyclin Analog, Ameliorates the Renal Alterations in a Mouse Type 2 Diabetes Model Possibly Through Its Protective Effects on Mesangial Cells

Watatani Hiroyuki,Yamasaki Hiroko,Maeshima Yohei,Nasu Tatsuyo,Hinamoto Norikazu,Ujike Haruyo,Sugiyama Hitoshi,Sakai Yoshiki,Tanabe Katsuyuki,Makino Hirofumi
Acta Medica Okayama 69(1), 1-15, 2015-02
… In cultured mouse mesangial cells, ONO-1301 concentration-dependently suppressed the increases in TGF-β, type IV collagen, α-SMA, MCP-1 and fibronectin induced by high ambient glucose, at least partly through prostacyclin (PGI2) receptor-mediated signaling. …
NAID 120005549937

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Journal of Oral Tissue Engineering 11(3), 227-233, 2014
… Fibronectin is decreased in chronically inflamed connective tissue, such as periodontitis. … Focal adhesion kinase (FAK) is a 125-kDa non-receptor type tyrosine kinase that localizes to focal adhesions. …
NAID 130004941115

Curcumin Ameliorates Renal Fibrosis by Inhibiting Local Fibroblast Proliferation and Extracellular Matrix Deposition

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Journal of Pharmacological Sciences, 2014
… Renal fibrosis is mainly characterized by activation and proliferation of interstitial fibroblasts and by excessive synthesis and accumulation of extracellular matrix (ECM) components, including fibronectin (FN) and collagen. … Protein expression of phosphorylated Smad2/3 (p-Smad2/3) and peroxisome proliferator-activated receptor-γ (PPAR-γ) were assessed by western blotting. …
NAID 130004933184