fibrinolytic agent

出典: meddic

antithrombotic agentfibrinolytic drugthrombolyticthrombolytic agentthrombolytic drugthrombolytics

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英文文献

  • Purification and characterization of tenerplasminin-1, a serine peptidase inhibitor with antiplasmin activity from the coral snake (Micrurus tener tener) venom.
  • Vivas J1, Ibarra C1, Salazar AM1, Neves-Ferreira AG2, Sánchez EE3, Perales J2, Rodríguez-Acosta A4, Guerrero B5.
  • Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.Comp Biochem Physiol C Toxicol Pharmacol.2016 Jan;179:107-15. doi: 10.1016/j.cbpc.2015.09.009. Epub 2015 Sep 28.
  • A plasmin inhibitor, named tenerplasminin-1 (TP1), was isolated from Micrurus tener tener (Mtt) venom. It showed a molecular mass of 6542Da, similarly to Kunitz-type serine peptidase inhibitors. The amidolytic activity of plasmin (0.5nM) on synthetic substrate S-2251 was inhibited by 91% following t
  • PMID 26419785
  • Acquired bleeding disorders in the elderly.
  • Kruse-Jarres R1.
  • Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program.Hematology Am Soc Hematol Educ Program.2015 Dec 5;2015(1):231-6. doi: 10.1182/asheducation-2015.1.231.
  • The hemostatic balance changes with advancing age which may be due to factors such as platelet activation, increase of certain clotting factor proteins, slowing of the fibrinolytic system, and modification of the endothelium and blood flow. Generally, this predisposes the elderly to thrombosis rathe
  • PMID 26637727
  • Impact of the Pla Protease Substrate α2-Antiplasmin on the Progression of Primary Pneumonic Plague.
  • Eddy JL1, Schroeder JA1, Zimbler DL1, Bellows LE1, Lathem WW2.
  • Infection and immunity.Infect Immun.2015 Dec;83(12):4837-47. doi: 10.1128/IAI.01086-15. Epub 2015 Oct 5.
  • Many pathogens usurp the host hemostatic system during infection to promote pathogenesis. Yersinia pestis, the causative agent of plague, expresses the plasminogen activator protease Pla, which has been shown in vitro to target and cleave multiple proteins within the fibrinolytic pathway, including
  • PMID 26438794

和文文献

  • Fibrinolytic enzyme from newly isolated marine bacterium Bacillus subtilis ICTF-1 : Media optimization, purification and characterization(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
  • Mahajan Prafulla M.,Nayak Shubhada,Lele Smita S.
  • Journal of bioscience and bioengineering 113(3), 307-314, 2012-03-00
  • Fibrinolytic enzymes are important in treatment of cardiovascular diseases. … The present work reports isolation, screening and identification of marine cultures for production of fibrinolytic enzymes. … A potent fibrinolytic enzyme-producing bacterium was isolated from marine niches and identified as Bacillus subtilis ICTF-1 on the basis of the 16S rRNA gene sequencing and biochemical properties. …
  • NAID 110009425320
  • 抗凝固薬/抗血小板薬/血栓溶解薬 (特集 救急領域における循環器用薬の使い方) -- (救急現場で必要な循環器用薬)
  • 菊島 公夫,長尾 健
  • 救急医学 34(12), 1643-1646, 2010-11-00
  • NAID 40017383406
  • Cerebellar Hemorrhage Provoked by Combined Use of Nattokinase and Aspirin in a Patient with Cerebral Microbleeds
  • Chang Yung-Yee,Liu Jia-Shou,Lai Shung-Lon,Wu Hsiu-Shan,Lan Min-Yu
  • Internal Medicine 47(5), 467-469, 2008
  • … Nattokinase is used as a health-promoting medicine for preventing thrombosis due to its fibrinolytic activity. … We suggest that nattokinase may increase risk of intracerebral hemorrhage in patients who have bleeding-prone cerebral microangiopathy and are receiving other antithrombotic agent at the same time. …
  • NAID 130000079714

関連リンク

Tissue plasminogen activator (t-PA) and urokinase are the agents that convert plasminogen to the active plasmin, thus allowing fibrinolysis to occur. t-PA is released into the blood very slowly by the damaged endothelium of the blood vessels, ...
Fibrinolytics may also be preferable in low-risk patients (i.e., patients with mortality risk < 4.0%) since PCI does not provide any mortality benefit over fibrinolytic therapy for these patients. Results of a recent study suggest that fibrinolytic agents ...

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★リンクテーブル★
先読み血栓溶解薬
リンク元thrombolytic」「thrombolytic drug」「thrombolytic agent」「antithrombotic agent」「線維素溶解薬
拡張検索antifibrinolytic agent
関連記事agent」「age」「fibrinolytic

血栓溶解薬」

  [★]

thrombolyticagent
-thrombolytics



thrombolytic」

  [★]

  • adj.
  • 血栓溶解の
  • n.
fibrinolytic agentthrombolysisthrombolytic agentthrombolytic drugthrombolytics

WordNet   license wordnet

「a kind of pharmaceutical that can break up clots blocking the flow of blood to the heart muscle」
thrombolytic agent, clot buster

thrombolytic drug」

  [★]

antithrombotic agentfibrinolytic agentfibrinolytic drugthrombolyticthrombolytic agentthrombolytics


thrombolytic agent」

  [★]

antithrombotic agentfibrinolytic agentfibrinolytic drugthrombolyticthrombolytic drug

antithrombotic agent」

  [★]

antithrombotic drugfibrinolytic agentfibrinolytic drugthrombolytic agentthrombolytic drug

線維素溶解薬」

  [★]

fibrinolytic agentfibrinolytic drug
血小板溶解薬血栓溶解薬抗血栓薬線溶剤


antifibrinolytic agent」

  [★]

antifibrinolyticantifibrinolyticsantiplasminplasmin inhibitor

agent」

  [★]

  • n.
  • 代行者、代理人。代理業者
  • 政府職員、官吏
  • ある後位をする人、ある作用をするもの。動員、動力因、作用因。(文法)動作主。科学的変化を起こさせるもの、薬品、~剤。病原体
agonistagonisticattorneydelegatedrugetiologic agentfomesfomitesmediatorpathogenpathogenicpharmaceutical preparationvectorvehicle

WordNet   license wordnet

「a substance that exerts some force or effect」

WordNet   license wordnet

「a businessman who buys or sells for another in exchange for a commission」
factor, broker

WordNet   license wordnet

「any agent or representative of a federal agency or bureau」
federal agent

WordNet   license wordnet

「a representative who acts on behalf of other persons or organizations」

WordNet   license wordnet

「an active and efficient cause; capable of producing a certain effect; "their research uncovered new disease agents"」

PrepTutorEJDIC   license prepejdic

「『代理人』;周旋人 / 働き(作用)を起こすもの;作用物,薬剤 / (政府機関,特にFBI,CIAなどの)部員,機関員」


age」

  [★]

  • n.
  • v.
  • 加齢する、熟成する
agedageingagingyear old

WordNet   license wordnet

「how long something has existed; "it was replaced because of its age"」

WordNet   license wordnet

「a time of life (usually defined in years) at which some particular qualification or power arises; "she was now of school age"; "tall for his eld"」
eld

WordNet   license wordnet

「begin to seem older; get older; "The death of his wife caused him to age fast"」

WordNet   license wordnet

「make older; "The death of his child aged him tremendously"」

PrepTutorEJDIC   license prepejdic

「〈U〉(一般に)『年齢』,寿命;〈C〉(個々の)『年齢』,年 / 〈U〉成年(おとなとしての資格・権利を得る年齢;通例18または21歳) / 〈U〉『老齢』;《集合的に》老人たち / 〈U〉(人生の)『一時期』;〈C〉世代(generation) / 〈U〉〈C〉《しばしばA-》(歴史上の)『時代』 / 〈C〉《話》長い間 / 年をとる,ふける;〈物が〉古くなる / 〈年〉'を'とらせる;〈物〉'を'古びさせる」

fibrinolytic」

  [★]

  • adj.
  • 線維素溶解性の、線維素溶解の、線溶の
fibrinolysis



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