フィブリン組織接着剤
- 関
- Tisseel
WordNet
- a soft thin (usually translucent) paper (同)tissue_paper
- part of an organism consisting of an aggregate of cells having a similar structure and function
- tending to adhere
- a white insoluble fibrous protein formed by the action of thrombin on fibrinogen when blood clots; it forms a network that traps red cells and platelets
PrepTutorEJDIC
- 〈U〉〈C〉(生物体の)『組織』 / 〈U〉〈C〉『薄織物』 / 〈U〉〈C〉水を吸収する柔らかな薄紙 / 〈C〉カーボンコピー用薄紙 / 〈C〉《a ~》(…を)織り交ぜて作ったもの《+of+名》 / =tissue paper
- 付着力のある,粘着性の / 粘着物,接着剤
- (凝固血液中の)線維素,フィブリン
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/08 04:30:22」(JST)
[Wiki en表示]
Fibrin glue applied after drying the scleral bed in an intraocular lens operation
Fibrin glue (also called fibrin sealant) is a formulation used to create a fibrin clot.[1][2][3][4][5][6][7]
Composition
It is made up of fibrinogen (lyophilised pooled human concentrate) and thrombin (bovine, which is reconstituted with calcium chloride)[1] that are applied to the tissue sites to glue them together.[1] Thrombin is an enzyme and converts fibrinogen into fibrin monomers between 10 and 60 seconds giving rise to a three-dimensional gel.[6][8]
Factors affecting structure
Factors that influence dimensional structure of fibrin gel giving rise to fine or coarse gel
- Changing concentration of fibrinogen
- Changing concentration of thrombine- increase concentration increases ultimate tensile strength and youngs modulus of gel
- Changing concentration of calcium
- pH
- Temperature
It may also contain aprotinin, fibronectin and plasminogen.[9] This glue can be used for repairing dura tears, bronchial fistulas and for achieving hemostasis after spleen and liver trauma.[6] It is also employed in "no sutures" corneal transplantation, pterygium excision with amniotic membrane or conjunctival autograft, and in ocular trauma for corneal or conjunctival defects.[10][11] [12]
References
- ^ a b c http://www.bmj.com/cgi/content/extract/308/6934/933
- ^ http://www.theannals.com/cgi/content/abstract/22/12/946
- ^ http://www.medhelp.org/forums/gastro/archive/1054.html
- ^ http://content.karger.com/ProdukteDB/produkte.asp?Doi=8552
- ^ http://www.healthsystem.virginia.edu/internet/stac/research/spfibgl.cfm
- ^ a b c http://www.ijps.org/article.asp?issn=0970-0358;year=2003;volume=36;issue=1;spage=14;epage=17;aulast=Saxena
- ^ http://www3.interscience.wiley.com/journal/121466570/abstract
- ^ Spotnitz, W. . (2009). "Fibrin Sealant: Past, Present, and Future: A Brief Review". World journal of surgery 34 (4): 632–634. doi:10.1007/s00268-009-0252-7. PMID 19820991. edit
- ^ Tisseel From the Swedish official drug catalog
- ^ Narendran N, Mohamed S, Shah S (July 2007). "No sutures corneal grafting--a novel use of overlay sutures and fibrin glue in Deep Anterior Lamellar Keratoplasty". Cont Lens Anterior Eye 30 (3): 207–9. doi:10.1016/j.clae.2007.02.007. PMID 17379570.
- ^ Dal Pizzol, MM; Roggia, MF; Kwitko, S; Marinho, DR; Rymer, S (2009). "Use of fibrin glue in ocular surgery". Arquivos brasileiros de oftalmologia 72 (3): 308–12. PMID 19668958. edit
- ^ Vivostat - Autologus Fibrin Sealant - PubMed link
UpToDate Contents
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- 1. 手術室で使用される局所止血剤の概要 overview of topical hemostatic agents used in the operating room
- 2. 肛門直腸瘻の手術管理 operative management of anorectal fistulas
- 3. 出血性の消化性潰瘍の治療 treatment of bleeding peptic ulcers
- 4. 活動性静脈瘤出血の治療 treatment of active variceal hemorrhage
- 5. 肺移植後の気道合併症 airway complications after lung transplantation
English Journal
- Multiple uses of fibrin sealant for nervous system treatment following injury and disease.
- Biscola NP1, Cartarozzi LP2, Ulian-Benitez S3, Barbizan R4, Castro MV2, Spejo AB2, Ferreira RS Jr5, Barraviera B5, Oliveira AL2.
- The journal of venomous animals and toxins including tropical diseases.J Venom Anim Toxins Incl Trop Dis.2017 Mar 14;23:13. doi: 10.1186/s40409-017-0103-1. eCollection 2017.
- PMID 28293254
- Plasminogen activator inhibitor-1 regulates macrophage-dependent postoperative adhesion by enhancing EGF-HER1 signaling in mice.
- Honjo K1,2, Munakata S1,2, Tashiro Y1,2, Salama Y1, Shimazu H1, Eiamboonsert S1, Dhahri D1, Ichimura A3, Dan T3, Miyata T3, Takeda K4, Sakamoto K2, Hattori K1,5, Heissig B6,4.
- FASEB journal : official publication of the Federation of American Societies for Experimental Biology.FASEB J.2017 Mar 7. pii: fj.201600871RR. doi: 10.1096/fj.201600871RR. [Epub ahead of print]
- PMID 28270519
- Efficacy of bubaline fibrin glue on full-thickness pinch and punch skin grafting in a pig.
- Dejyong K1, Kaewamatawong T2, Brikshavana P1, Durongphongtorn S1.
- Journal of biomaterials applications.J Biomater Appl.2017 Mar;31(8):1215-1224. doi: 10.1177/0885328217693126. Epub 2017 Feb 9.
- PMID 28181448
Japanese Journal
- Spontaneous Hemothorax Associated with von Recklinghausen's Disease : Report of a Case
- MIYAZAKI Takuro,TSUCHIYA Tomoshi,TAGAWA Tsutomu,YAMASAKI Naoya,NAGAYASU Takeshi
- Annals of thoracic and cardiovascular surgery 17(3), 301-303, 2011-06-01
- … We performed direct surgical ligation of the bleeding vessel with a fibrin tissue-adhesive collagen fleece. …
- NAID 10029687179
- 白石 裕介,早川 希,若松 太郎 [他],吉田 一彦,矢西 正明,冨田 英里,宮内 勇貴,白川 浩希,清水 朋一,石田 英樹,田邉 一成
- 日本泌尿器科學會雜誌 102(3), 595-599, 2011-05-20
- 移植腎破裂は頻度は低いものの腎移植における重大な合併症である.その最大の原因は急性拒絶であるが,免疫抑制剤療法の進歩により他の原因の頻度が増えてきている.今回われわれは就寝中の咳嗽を契機に移植腎破裂をおこした1例を報告する.症例は53歳男性,糖尿病性腎症による末期腎不全のため当科で妻をドナーとするABO血液型不一致(O→B)生体腎移植術を施行した.臨床経過は良好で術後12日目にCr1.24で退院し …
- NAID 110008661933
- 白石 裕介,早川 希,若松 太郎,吉田 一彦,矢西 正明,冨田 英里,宮内 勇貴,白川 浩希,清水 朋一,石田 英樹,田邉 一成
- 日本泌尿器科学会雑誌 102(3), 595-599, 2011
- 移植腎破裂は頻度は低いものの腎移植における重大な合併症である．その最大の原因は急性拒絶であるが，免疫抑制剤療法の進歩により他の原因の頻度が増えてきている．今回われわれは就寝中の咳嗽を契機に移植腎破裂をおこした1例を報告する． 症例は53歳男性，糖尿病性腎症による末期腎不全のため当科で妻をドナーとするABO血液型不一致（O→B）生体腎移植術を施行した．臨床経過は良好で術後12日目にCr1.24で退院 …
- NAID 130002146429
★リンクテーブル★
[★]
- 英
- fibrin tissue adhesive
- 関
- ティシール
[★]
ティシール
- 関
- fibrin tissue adhesive
[★]
- 関
- accretion、adhere、adherence、adherent、adhesion、adhesive property、adhesiveness、adhesives、coalesce、coalescence、coalescent、cohesion、cohesive、cohesiveness、glue、symphysial
[★]
- 関
- adhesive、glue、mucilage