WordNet

a white insoluble fibrous protein formed by the action of thrombin on fibrinogen when blood clots; it forms a network that traps red cells and platelets
a simple compound whose molecules can join together to form polymers

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1. 血栓溶解異常による血栓性および出血性疾患 thrombotic and hemorrhagic disorders due to abnormal fibrinolysis
2. フィブリノゲンの異常 disorders of fibrinogen
3. 手術室で使用される局所止血剤および組織接着剤の概要 overview of topical hemostatic agents and tissues adhesives used in the operating room
4. 成人における確定診断を得られていない低血圧やショックの評価および初期アプローチ evaluation of and initial approach to the adult patient with undifferentiated hypotension and shock
5. フィブリンシーラント fibrin sealant

Trauma-Induced Coagulopathy Is Associated with a Complex Inflammatory Response in the Rat.

Darlington DN1, Gonzales MD, Craig T, Dubick MA, Cap AP, Schwacha MG.
Shock (Augusta, Ga.).Shock.2015 Aug;44 Suppl 1:129-37. doi: 10.1097/SHK.0000000000000354.
Severe trauma can lead to a coagulopathy in patients, which is associated with increased mortality. We developed a rat polytrauma model that demonstrates a similar progression of coagulopathy. Because coagulation is influenced by changes in inflammation, and this interrelationship is poorly understo
PMID 25664984

Accelerated activation of the coagulation pathway during cardiopulmonary bypass in aortic replacement surgery: a prospective observational study.

Sato H1, Yamamoto K2, Kakinuma A3, Nakata Y4, Sawamura S5.
Journal of cardiothoracic surgery.J Cardiothorac Surg.2015 Jun 23;10(1):84. doi: 10.1186/s13019-015-0295-9.
BACKGROUND: Any form of surgery or tissue damage causes release of tissue factor into the circulation. This may lead to the accelerated consumption of coagulation factors, resulting in severe consumptive coagulopathy. In this study, we compared the molecular markers involved in coagulation activatio
PMID 26099510

Rosenfeld MA1, Leonova VB2, Shchegolikhin AN2, Bychkova AV2, Kostanova EA2, Biryukova MI2.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2015 May 29;461(2):408-12. doi: 10.1016/j.bbrc.2015.04.052. Epub 2015 Apr 18.
FXIIIa-mediated isopeptide γ-γ bonds are produced between γ polypeptide chains of adjacent monomeric fibrin. Despite the use of the different methodological approaches there are apparently conflicting ideas regarding the orientation of γ-γ bonds. To identify the orientation of these bonds a nov
PMID 25896761

Hemostatic mechanisms of a soluble fraction of plant-derived sodium carboxymethyl cellulose

AOSHIMA Motonori,KOHNO Isao,JO Yoshio,TAKAHASHI Kei,SUGO Teruko,MATSUDA Michio
日本血栓止血学会誌 23(4), 387-398, 2012
… The Sol-CM was found to enhance polymerization of fibrin monomers in a concentration-dependent fashion, without stimulating the activation of proenzymes, such as prothrombin, that are involved in the blood coagulation process. … Fibrin fibers that formed in the presence of Sol-CM appeared to be thicker than those formed in its absence and Sol-CM was incorporated into them in the scanning electron microscopic study. …
NAID 130004484936