fertile

出典: meddic

  • adj.
  • (土地が)肥えた、肥沃な、豊穣な(opp.sterile)。多産な。方策をもたらす
  • [fig]豊かな、実り多い。想像力に富む、創意豊かな
  • (生)繁殖力のある。(生)受精した(fertilized)


fertility

WordNet   license wordnet

「capable of reproducing」

PrepTutorEJDIC   license prepejdic

「(土地が)『肥沃(ひよく)な』,作物のよくできる / (動植物が)繁殖力のある / (種子などが)生育力のある;(卵が)受精した(fertilized) / (精神などが)創造力の豊かな」

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/19 21:14:16」(JST)

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英文文献

  • Low-dose gold nanoparticles exert subtle endocrine-modulating effects on the ovarian steroidogenic pathway ex vivo independent of oxidative stress.
  • Larson JK1, Carvan MJ 3rd, Teeguarden JG, Watanabe G, Taya K, Krystofiak E, Hutz RJ.Author information 1University of Wisconsin-Milwaukee, Biological Sciences , Milwaukee, WI , USA.AbstractGold nanoparticles (GNPs) have gained considerable attention for application in science and industry. However, the untoward effects of such particles on female fertility remain unclear. The objectives of this study were to (1) examine the effects of 10-nm GNPs on progesterone and estradiol-17β accumulation by rat ovaries ex vivo and (2) to identify the locus/loci whereby GNPs modulate steroidogenesis via multiple-reference gene quantitative real-time RT-PCR. Regression analyses indicated a positive relationship between both Star (p < 0.05, r(2) = 0.278) and Cyp11a1 (p < 0.001, r(2) = 0.366) expression and P4 accumulation upon exposure to 1.43 × 10(6) GNPs/mL. Additional analyses showed that E2 accumulation was positively associated with Hsd3b1 (p < 0.05, r(2) = 0.181) and Cyp17a1 (p < 0.01, r(2) = 0.301) expression upon exposure to 1.43 × 1(3) and 1.43 × 10(9) GNPs/mL, respectively. These results suggest a subtle treatment-dependent impact of low-dose GNPs on the relationship between progesterone or estradiol-17β and specific steroidogenic target genes, independent of oxidative stress or inhibin.
  • Nanotoxicology.Nanotoxicology.2014 Dec;8(8):856-66. doi: 10.3109/17435390.2013.837208.
  • Gold nanoparticles (GNPs) have gained considerable attention for application in science and industry. However, the untoward effects of such particles on female fertility remain unclear. The objectives of this study were to (1) examine the effects of 10-nm GNPs on progesterone and estradiol-17β accu
  • PMID 23992423
  • Combined repeated-dose toxicity study of silver nanoparticles with the reproduction/developmental toxicity screening test.
  • Hong JS1, Kim S, Lee SH, Jo E, Lee B, Yoon J, Eom IC, Kim HM, Kim P, Choi K, Lee MY, Seo YR, Kim Y, Lee Y, Choi J, Park K.Author information 1Korea Testing and Research Institute, Health Care Research and Creation , Gimpo , Korea.AbstractCombined repeated-dose toxicity study of citrate-capped silver nanoparticles (7.9 ± 0.95 nm) with reproduction/developmental toxicity was investigated in rats orally treated with 62.5, 125 and 250 mg/kg, once a day for 42 days for males and up to 52 days for females. The test was performed based on the Organization for Economic Cooperation and Development test guideline 422 and Good Laboratory Practice principles. No death was observed in any of the groups. Alopecia, salivation and yellow discolouration of the lung were observed in a few rats but the symptoms were not dose-dependent. Haematology, serum biochemical investigation and histopathological analysis revealed no statistically significant differences between control group and the treated groups. Toxicity endpoints of reproduction/developmental screening test including mating, fertility, implantation, delivery and foetus were measured. There was no evidence of toxicity.
  • Nanotoxicology.Nanotoxicology.2014 Jun;8(4):349-62. doi: 10.3109/17435390.2013.780108. Epub 2013 Mar 19.
  • Combined repeated-dose toxicity study of citrate-capped silver nanoparticles (7.9 ± 0.95 nm) with reproduction/developmental toxicity was investigated in rats orally treated with 62.5, 125 and 250 mg/kg, once a day for 42 days for males and up to 52 days for females. The test was performed based on
  • PMID 23432083
  • The effect of group X secreted phospholipase A2 on fertilization outcome is specific and not mimicked by other secreted phospholipases A2 or progesterone.
  • Abi Nahed R1, Escoffier J1, Revel C2, Jeammet L2, Payré C2, Ray PF3, Hennebicq S4, Lambeau G2, Arnoult C5.Author information 1Université Joseph Fourier, Grenoble F-38000, France; Laboratoire AGIM, Equipe AGC, CNRS FRE3405, La Tronche F-38700, France.2Institut de Pharmacologie Moléculaire et Cellulaire, CNRS - UMR 7275, Valbonne, France; Université de Nice-Sophia Antipolis, Valbonne, France.3Université Joseph Fourier, Grenoble F-38000, France; Laboratoire AGIM, Equipe AGC, CNRS FRE3405, La Tronche F-38700, France; CHU de Grenoble, UF de Biochimie et Génétique Moléculaire, Grenoble F-38000, France.4Université Joseph Fourier, Grenoble F-38000, France; Laboratoire AGIM, Equipe AGC, CNRS FRE3405, La Tronche F-38700, France; CHU de Grenoble, Centre d'AMP-CECOS, BP217, Grenoble cedex 9 F-38043, France.5Université Joseph Fourier, Grenoble F-38000, France; Laboratoire AGIM, Equipe AGC, CNRS FRE3405, La Tronche F-38700, France. Electronic address: christophe.arnoult@ujf-grenoble.fr.AbstractMouse group X sPLA2 (mGX) is an acrosomal protein playing an important role in fertilization and controlling acrosome reaction (AR) occurring during capacitation. We demonstrated previously that sperm from mGX knock-out mice had a severely impaired fertilization potential in vitro. We also showed that treatment of wild-type sperm with recombinant mGX during capacitation improved fertilization outcome. This interesting property suggests that sPLA2s could be used to improve fertilization in assisted reproductive technologies (ART). However the molecular mechanism explaining the mGX-dependent enhancing effect on fertilization outcome remains unclear so far. Interestingly, like progesterone (P4), mGX is a very potent activator of AR and the role of mGX-induced AR in fertilization outcome was not evaluated so far. To assess the role of sPLA2-induced AR in IVF, we first tested the potency of 9 mouse and 2 human sPLA2s and P4 to trigger AR of mouse sperm. We then tested the ability of 6 of these molecules (mouse Group IIA, mouse Group IID, mouse Group X, human Group V, human Group X and P4) to improve the yield of 2-cell embryos obtained by IVF in mouse. We showed that in the mouse neither P4 nor any of the other sPLA2s tested were able to mimic the IVF improvement produced by mGX-treatment. These results demonstrate that sPLA2s are not commutable in the context of mouse sperm fertility, indicating that their utilisation in other species, is subjected to the identification of probably unique species-specific active sPLA2.
  • Biochimie.Biochimie.2014 Apr;99:88-95. doi: 10.1016/j.biochi.2013.11.012. Epub 2013 Nov 25.
  • Mouse group X sPLA2 (mGX) is an acrosomal protein playing an important role in fertilization and controlling acrosome reaction (AR) occurring during capacitation. We demonstrated previously that sperm from mGX knock-out mice had a severely impaired fertilization potential in vitro. We also showed t
  • PMID 24287291
  • Iron status as a covariate in methylmercury-associated neurotoxicity risk.
  • Fonseca Mde F1, De Souza Hacon S2, Grandjean P3, Choi AL4, Bastos WR5.Author information 1Instituto Fernandes Figueira, Fundação Oswaldo Cruz, Av. Rui Barbosa 716, Flamengo, Rio de Janeiro, RJ 22250-020, Brazil; Department of Environmental Health, Harvard School of Public Health, 401 Park Drive, Landmark Center Room 3-110 East, Boston, MA 02215, USA. Electronic address: marlon@iff.fiocruz.br.2Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, Av. Brasil 4365, Manguinhos, Rio de Janeiro, RJ 21040-900, Brazil. Electronic address: sandrahacon@gmail.com.3Department of Environmental Health, Harvard School of Public Health, 401 Park Drive, Landmark Center Room 3-110 East, Boston, MA 02215, USA; Institute of Public Health, University of Southern Denmark, J.B. Winsløws Vej 17A/2, DK-5000 Odense C, Denmark. Electronic address: pgrand@hsph.harvard.edu.4Department of Environmental Health, Harvard School of Public Health, 401 Park Drive, Landmark Center Room 3-110 East, Boston, MA 02215, USA.5Laboratório de Biogeoquímica Ambiental Wolfgang Christian Pfeiffer, Universidade Federal de Rondônia, Rodovia BR 364 Km 9,5 Sentido Acre, Zona Rural, Porto Velho, RO 76801-974, Brazil. Electronic address: wanderbastos@yahoo.com.br.AbstractIntrauterine methylmercury exposure and prenatal iron deficiency negatively affect offspring's brain development. Since fish is a major source of both methylmercury and iron, occurrence of negative confounding may affect the interpretation of studies concerning cognition. We assessed relationships between methylmercury exposure and iron-status in childbearing females from a population naturally exposed to methylmercury through fish intake (Amazon). We concluded a census (refuse <20%) collecting samples from 274 healthy females (12-49years) for hair-mercury determination and assessed iron-status through red cell tests and determination of serum ferritin and iron. Reactive C protein and thyroid hormones was used for excluding inflammation and severe thyroid dysfunctions that could affect results. We assessed the association between iron-status and hair-mercury by bivariate correlation analysis and also by different multivariate models: linear regression (to check trends); hierarchical agglomerative clustering method (groups of variables correlated with each other); and factor analysis (to examine redundancy or duplication from a set of correlated variables). Hair-mercury correlated weakly with mean corpuscular volume (r=.141; P=.020) and corpuscular hemoglobin (r=.132; .029), but not with the best biomarker of iron-status, ferritin (r=.037; P=.545). In the linear regression analysis, methylmercury exposure showed weak association with age-adjusted ferritin; age had a significant coefficient (Beta=.015; 95% CI: .003-.027; P=.016) but ferritin did not (Beta=.034; 95% CI: -.147 to .216; P=.711). In the hierarchical agglomerative clustering method, hair-mercury and iron-status showed the smallest similarities. Regarding factor analysis, iron-status and hair-mercury loaded different uncorrelated components. We concluded that iron-status and methylmercury exposure probably occur in an independent way.
  • Chemosphere.Chemosphere.2014 Apr;100:89-96. doi: 10.1016/j.chemosphere.2013.12.053. Epub 2014 Jan 8.
  • Intrauterine methylmercury exposure and prenatal iron deficiency negatively affect offspring's brain development. Since fish is a major source of both methylmercury and iron, occurrence of negative confounding may affect the interpretation of studies concerning cognition. We assessed relationships b
  • PMID 24411835

和文文献

関連リンク

Fertility is the natural capability of producing offsprings. As a measure, "fertility rate" is the number of children born per couple, person or population. Fertility differs from fecundity, which is defined as the potential for reproduction ( influenced by ...
Fertile material is a material that, while not itself fissionable by thermal neutrons, can be converted into a fissile material by neutron absorption and subsequent nuclei conversions. Naturally-occurring fertile materials that can be converted into ...

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★リンクテーブル★
先読みsterile
リンク元fertility」「稔性」「繁殖性
拡張検索fertile period」「infertile」「fertile leaves」「fertile eunuch syndrome

sterile」

  [★]


WordNet   license wordnet

「deficient in originality or creativity; lacking powers of invention; "a sterile ideology lacking in originality"; "unimaginative development of a musical theme"; "uninspired writing"」
unimaginative, uninspired, uninventive

PrepTutorEJDIC   license prepejdic

「不妊の,子を生まない(barren) / (土地が)不毛の,やせた(barren) / 無菌の,殺菌した / (考え方・話などが)想像力に乏しい,ありきたりの,陳腐な」

WordNet   license wordnet

「incapable of reproducing; "an infertile couple"」
unfertile, infertile


fertility」

  [★]

fertile + -ity
  • n.
  • 土地が肥えていること、肥沃(⇔sterility)。肥沃の度合い
  • 多産、繁殖力\生殖力のあること
  • (想像力などの)豊かさ
  • 出生率
fertile

WordNet   license wordnet

「the state of being fertile; capable of producing offspring」
fecundity

PrepTutorEJDIC   license prepejdic

「肥沃(ひよく);産出力,繁殖力;(創造力の)豊かさ」


稔性」

  [★]

fertilityfertile
受精能受精率繁殖性肥料分受胎能妊孕性妊孕能


繁殖性」

  [★]

fertilityfertile
受精能受精率稔性肥料分受胎能妊孕性妊孕能


fertile period」

  [★]

WordNet   license wordnet

「the time in the menstrual cycle when fertilization is most likely to be possible (7 days before to 7 days after ovulation)」
fertile phase


infertile」

  [★]

  • adj.
  • 不妊の
infecundityinfertilitysterility

PrepTutorEJDIC   license prepejdic

「(土地が)肥えてない,不毛の(barren)」


fertile leaves」

  [★] 胞子葉

fertile leafsporophyll


fertile eunuch syndrome」

  [★] 生殖可能類宦官症候群


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