fenfluramine

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/05/25 00:11:56」(JST)

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英文文献

  • Serotonergic anti-obesity agents: past experience and future prospects.
  • Halford JC, Boyland EJ, Lawton CL, Blundell JE, Harrold JA.SourceExperimental Psychology, University of Liverpool, Liverpool, UK.
  • Drugs.Drugs.2011 Dec 3;71(17):2247-55. doi: 10.2165/11596680-000000000-00000.
  • The role of serotonin (5-hydroxytryptamine) in appetite control is long established. Serotonergic manipulations reduce food intake in rodents in a manner consistent with satiety. In humans, drugs such as fenfluramine, dexfenfluramine and sibutramine all reduce energy intake, suppress hunger and enha
  • PMID 22085383
  • Effects of fenfluramine, 8-OH-DPAT, and tryptophan-enriched diet on the high-ethanol intake by rats bred for susceptibility to stress.
  • West CH, Boss-Williams KA, Weiss JM.SourceDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30306, USA.
  • Alcohol (Fayetteville, N.Y.).Alcohol.2011 Dec;45(8):739-49. Epub 2011 Sep 15.
  • The swim-test susceptible (SUS) line of rats has been bred in our laboratory for the characteristic of reduced motor activity in the swim test following exposure to an acute stressor. Testing of multiple generations of SUS rats has also revealed that they consume large amounts of ethanol voluntarily
  • PMID 21924578

和文文献

  • 国立医薬品食品衛生研究所における痩身や強壮を標榜する健康食品中の医薬品成分の分析と同定
  • Enhanced Behavioral Response to Serotonin-Related Agonists in Postweaning Protein Malnourished Mice
  • In vivo incorporation of fenfluramine and norfenfluramine into pigmented and nonpigmented hair of rats measured by HPLC-fluorescence detection

関連リンク

Fenfluramine (3-trifluoromethyl-N-ethylamphetamine, trade names Pondimin, Ponderax and Adifax) is a drug that was part of the Fen-Phen anti-obesity medication (the other drug being phentermine). Fenfluramine was introduced on the U.S. ...

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File:Fenfluramine.svg - Wikimedia CommonsFigure 1. Fenfluramine.Fenfluramine diet pills: Fenfluramine (PondiminFenfluramine , the prototypical SSRA File:Fenfluramine.svg - Wikipedia, the


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  • During the 1990s, the commonly used weight-loss drug combination of fenfluramine and phenteramine was, is some patients, associated with the development of thickedned plaques on the cardiac valves. These patients were prone to develop MR, as well as aortic regurgitaion and tricuspid valve disease. (PPC. 204)


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