WordNet

relating to or having the characteristics of a family; "children of the same familial background"; "familial aggregation"
occurring among members of a family usually by heredity; "an inherited disease"; "familial traits"; "genetically transmitted features" (同)genetic, hereditary, inherited, transmitted, transmissible
any malignant tumor derived from epithelial tissue; one of the four major types of cancer
relating to the prostate gland (同)prostatic

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Design, Synthesis, and Biological Evaluation of Unconventional Aminopyrimidine, Aminopurine, and Amino-1,3,5-triazine Methyloxynucleosides.

Fernández-Cureses G1, de Castro S, Jimeno ML, Balzarini J, Camarasa MJ.
ChemMedChem.ChemMedChem.2015 Feb;10(2):321-35. doi: 10.1002/cmdc.201402465. Epub 2014 Nov 24.
Herein we describe a class of unconventional nucleosides (methyloxynucleosides) that combine unconventional nucleobases such as substituted aminopyrimidines, aminopurines, or aminotriazines with unusual sugars in their structures. The allitollyl or altritollyl derivatives were pursued as ribonucleos
PMID 25420933

NR2F1 controls tumour cell dormancy via SOX9- and RARβ-driven quiescence programmes.

Sosa MS1, Parikh F2, Maia AG3, Estrada Y1, Bosch A1, Bragado P1, Ekpin E1, George A1, Zheng Y4, Lam HM5, Morrissey C5, Chung CY3, Farias EF6, Bernstein E7, Aguirre-Ghiso JA8.
Nature communications.Nat Commun.2015 Jan 30;6:6170. doi: 10.1038/ncomms7170.
Metastases can originate from disseminated tumour cells (DTCs), which may be dormant for years before reactivation. Here we find that the orphan nuclear receptor NR2F1 is epigenetically upregulated in experimental head and neck squamous cell carcinoma (HNSCC) dormancy models and in DTCs from prostat
PMID 25636082

Li S, Zhu Y, Ma C, Qiu Z, Zhang X, Kang Z, Wu Z, Wang H, Xu X, Zhang H, Ren G, Tang J, Li X, Guan M.
BMC cancer.BMC Cancer.2015 Jan 22;15(1):18. [Epub ahead of print]
BackgroundEphA5 is a member of the Eph/ephrin family and plays a critical role in the regulation of carcinogenesis. A significant reduction of EphA5 transcripts in high-grade prostate cancer tissue was shown using a transcriptomic analysis, compared to the low-grade prostate cancer tissue. As less i
PMID 25609195

Genetic polymorphisms of estrogen receptor alpha, CYP19, catechol-O-methyltransferase are associated with familial prostate carcinoma risk in a Japanese population

本田勇二,河野哲夫,田中暢之,江口英雄
日本臨床外科学会雑誌 63(10), 2585-2590, 2002
34年間で異時性に4個の大腸癌と1個の小腸癌を重複した症例を経験したので報告する.症例は81歳,男性.家族歴に特記事項はなかった.昭和44年他院にて直腸癌の診断で直腸切断術を施行した.その後通院しておらず平成4年9月下血を主訴に来院, 11月9日横行結腸癌にて横行結腸切除術を施行した.術後テガフールの内服を18ヵ月間行った.その間平成5年9月28日に前立腺肥大症にて前立腺全摘術,平成6年5月19日 …
NAID 130003602793

石川正志,田村利和,川人幹也,国友一史,宇高英憲,古味信彦
日本大腸肛門病学会雑誌 39(3), 218-222, 1986
昭和50年1月から59年12月までの過去10年間に経験した大腸多発癌14例(同時性多発癌11例(7.1%),異時性多発癌3例(1.9%)),大腸重複癌7例(4.5%)を大腸単発癌132例と比較検討した.性比では多発癌は男:女=10:4であり,重複癌では2:5であり,重複癌では女性に多い傾向が見られた.同時性多発癌では第1癌と第2癌で組織型に差異を認めなかったが,進行癌と早期癌の組み合わせが6例(5 …
NAID 130000782770