familial hypertriglyceridemia

家族性高トリグリセリド血症

関

hyperlipoproteinemia type IV

同

FHTG

WordNet

1. relating to or having the characteristics of a family; "children of the same familial background"; "familial aggregation"
2. occurring among members of a family usually by heredity; "an inherited disease"; "familial traits"; "genetically transmitted features" (同)genetic, hereditary, inherited, transmitted, transmissible

PrepTutorEJDIC

1. 家族の,家族特有の / 違伝的な,血統にあらわれる

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/20 18:26:13」(JST)

wiki en

[Wiki en表示]

Familial hypertriglyceridemia is an autosomal dominant condition occurring in approximately 1% of the population. Triglyceride levels, but not cholesterol, are elevated as a result of excess hepatic production of VLDL or heterozygous LPL deficiency. Unlike familial hypercholesterolemia, there is no association with premature coronary disease. However, affected individuals are at risk for chylomicronemia syndrome, characterized by elevated chylomicrons in the blood.

See also

• Primary hyperlipoproteinemia
• Familial apoprotein CII deficiency
• Skin lesion

References

UpToDate Contents

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• 1. Hypertriglyceridemia
• 2. 小児における脂質異常症：定義、スクリーニングおよび診断 dyslipidemia in children definition screening and diagnosis
• 3. 二次予防における脂質（高コレステロール血症を含む）の治療 treatment of lipids including hypercholesterolemia in secondary prevention
• 4. 甲状腺疾患における脂質異常 lipid abnormalities in thyroid disease
• 5. 妊娠時の肝胆道系疾患併発 intercurrent hepatobiliary disease during pregnancy

English Journal

• Novel therapies for severe dyslipidemia originating from human genetics.

• Gaudet D1.
• Current opinion in lipidology.Curr Opin Lipidol.2016 Apr;27(2):112-24. doi: 10.1097/MOL.0000000000000281.
• PURPOSE OF REVIEW: Novel therapies for severe dyslipidemia target a wide range of unmet medical needs: severe familial hypercholesterolemia, severe hypertriglyceridemia and chylomicronemia, elevated lipoprotein (a), lipodystrophies, high-density lipoprotein particle diseases, lysosomal acid lipase d
• PMID 26849851

• A case of familial partial lipodystrophy caused by a novel lamin A/C (LMNA) mutation in exon 1 (D47N).

• Kutbay NO1, Yurekli BS2, Onay H3, Altay CT4, Atik T3, Hekimsoy Z5, Saygili F2, Akinci B6.
• European journal of internal medicine.Eur J Intern Med.2016 Apr;29:37-9. doi: 10.1016/j.ejim.2015.12.012. Epub 2016 Jan 7.
• BACKGROUND: Familial partial lipodystrophy (FPL) is a rare genetic disorder characterized by selective lack of subcutaneous fat which is associated with insulin resistant diabetes. The Dunnigan variety (FPL2) is caused by several missense mutations in the lamin A/C (LMNA) gene, most of which are typ
• PMID 26775134

• Reduction in lipoprotein-associated apoC-III levels following volanesorsen therapy: phase 2 randomized trial results.

• Yang X1, Lee SR2, Choi YS3, Alexander VJ4, Digenio A5, Yang Q4, Miller YI6, Witztum JL6, Tsimikas S7.
• Journal of lipid research.J Lipid Res.2016 Apr;57(4):706-13. doi: 10.1194/jlr.M066399. Epub 2016 Feb 4.
• Elevated apoC-III levels predict increased cardiovascular risk when present on LDL and HDL particles. We developed novel high-throughput chemiluminescent ELISAs that capture apoB, lipoprotein (a) [Lp(a)], and apoA-I in plasma and then detect apoC-III on these individual lipoproteins as apoCIII-apoB,
• PMID 26848137

Japanese Journal

• Reference Interval for the Apolipoprotein B-48 Concentration in Healthy Japanese Individuals

• Masuda Daisaku,Nishida Makoto,Arai Toshihiko,Hanada Hiroyuki,Yoshida Hiroshi,Yamauchi-Takihara Keiko,Moriyama Toshiki,Tada Norio,Yamashita Shizuya
• Journal of Atherosclerosis and Thrombosis 21(6), 618-627, 2014
• … Aim: Small intestine-derived chylomicrons and chylomicron remnants, which are predominant in patients with postprandial hypertriglyceridemia, chylomicron syndrome and/or familial dyslipidemia, carry one molecule of apolipoprotein B-48(apo B-48) per lipoprotein particle. …
• NAID 130004444752

• Apolipoprotein C-II Deficiency with No Rare Variant in the APOC2 Gene

• Takase Satoru,Osuga Jun-ichi,Fujita Hayato,Hara Kazuo,Sekiya Motohiro,Igarashi Masaki,Takanashi Mikio,Takeuchi Yoshinori,Izumida Yoshihiko,Ohta Keisuke,Kumagai Masayoshi,Nishi Makiko,Kubota Midori,Masuda Yukari,Taira Yoshino,Okazaki Sachiko,Iizuka Yoko,Yahagi Naoya,Ohashi Ken,Yoshida Hiroshi,Yanai Hidekatsu,Tada Norio,Gotoda Takanari,Ishibashi Shun,Kadowaki Takashi,Okazaki Hiroaki
• Journal of Atherosclerosis and Thrombosis 20(5), 481-493, 2013
• … Aim: Familial apolipoprotein C-II (apoC-II) deficiency is a rare autosomal recessive disorder with marked hypertriglyceridemia resulting from impaired activation of lipoprotein lipase. …
• NAID 130004444688

• Premature Atherosclerosis in a Japanese Diabetic Patient with Atypical Familial Partial Lipodystrophy and Hypertriglyceridemia

• Iwanishi Masanori,Ebihara Ken,Kusakabe Toru,Harada Shinji,Ito-Kobayashi Jun,Tsuji Atsushi,Hosoda Kiminori,Nakao Kazuwa
• Internal Medicine 51(18), 2573-2579, 2012
• … We herein report a case of premature atherosclerosis in a patient with familial partial lipodystrophy (FPL), diabetes mellitus, hypertension and hypertriglyceridemia. …
• NAID 130002062378

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★リンクテーブル★

リンク元	「hyperlipoproteinemia type IV」「家族性高リポ蛋白血症IV型」「家族性高トリグリセリド血症」「FHTG」
関連記事	「familial」「hypertriglyceridemia」「hypertriglyceridemias」

「hyperlipoproteinemia type IV」

　　[★] (TG上昇を特徴とする家族性リポ蛋白過剰症)高リポ蛋白血症IV型、高リポ蛋白血症4型、IV型高リポ蛋白血症、4型高リポ蛋白血症

関

familial hypertriglyceridemia、type IV hyperlipoproteinemia

「家族性高リポ蛋白血症IV型」

　　[★]

英

familial hyperlipoproteinemia type IV

同

家族性高トリグリセリド血症 familial hypertriglyceridemia

関

高リポ蛋白血症

「家族性高トリグリセリド血症」

　　[★]

英

familial hypertriglyceridemia

関

4型高リポ蛋白血症、家族性高リポ蛋白血症IV型

「FHTG」

　　[★]

同

familial hypertriglyceridemia

「familial」

　　[★]

• adj.

• 家族性の、家系性の、家族の

関

family、family member、household、kindred

　 　 　

「hypertriglyceridemia」

　　[★] 高トリグリセリド血症

「hypertriglyceridemias」

　　[★] 高トリグリセリド血症