WordNet

relating to or having the characteristics of a family; "children of the same familial background"; "familial aggregation"
occurring among members of a family usually by heredity; "an inherited disease"; "familial traits"; "genetically transmitted features" (同)genetic, hereditary, inherited, transmitted, transmissible
a pass between mountain peaks (同)gap

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Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling.

Miao CG, Yang YY, He X, Li XF, Huang C, Huang Y, Zhang L, Lv XW, Jin Y, Li J.SourceSchool of Pharmacy, Institute for Liver Diseases of Anhui Medical University, Anhui Key Laboratory of Bioactivity of Natural Products, Anhui Medical University, Hefei 230032, China; School of Food and Drug, Anhui Science and Technology University, Bengbu 233100, China.
Cellular signalling.Cell Signal.2013 Oct;25(10):2069-78. doi: 10.1016/j.cellsig.2013.04.002. Epub 2013 Apr 17.
Rheumatoid arthritis (RA) is a chronic symmetrical autoimmune disease of unknown etiology that affects primarily the diarthrodial joints. Characteristic features of RA pathogenesis are synovial inflammation and proliferation accompanied by cartilage erosion and bone loss. Fibroblast-like synoviocyte
PMID 23602936

Relationship among expression of basic-fibroblast growth factor, MTDH/Astrocyte elevated gene-1, adenomatous polyposis coli, matrix metalloproteinase 9,and COX-2 markers with prognostic factors in prostate carcinomas.

Erdem H, Yildirim U, Uzunlar AK, Cam K, Tekin A, Kayikci MA, Sahiner C, Oktay M, Ankarali H, Aydin LY.SourceDepartment of Pathology, Duzce University Medical Faculty, Duzce, Turkey.
Nigerian journal of clinical practice.Niger J Clin Pract.2013 Oct-Dec;16(4):418-23. doi: 10.4103/1119-3077.116873.
Background: The etiopathogenesis of prostate cancer (PC) is still not clear, but hormonal, genetic, and environmental factors are thought to play a role in the tumor pathogenesis. Astrocyte elevated gene-1(AEG-1) as a novel transmembrane protein is predominantly located in the perinuclear region and
PMID 23974731

β-catenin at the centrosome: Discrete pools of β-catenin communicate during mitosis and may co-ordinate centrosome functions and cell cycle progression.

Mbom BC, Nelson WJ, Barth A.SourceDepartment of Biology, Stanford University, Stanford, CA, USA.
BioEssays : news and reviews in molecular, cellular and developmental biology.Bioessays.2013 Sep;35(9):804-9. doi: 10.1002/bies.201300045. Epub 2013 Jun 27.
Beta-catenin is a multifunctional protein with critical roles in cell-cell adhesion, Wnt-signaling and the centrosome cycle. Whereas the roles of β-catenin in cell-cell adhesion and Wnt-signaling have been studied extensively, the mechanism(s) involving β-catenin in centrosome functions are poorly
PMID 23804296

星野大樹,石井良幸,長谷川博俊,遠藤高志,落合大樹,星野好則,松永篤志,茂田浩平,瀬尾雄樹,星野剛,向井万起男,北川雄光
日本大腸肛門病学会雑誌 65(3), 118-123, 2012
症例は78歳の男性で，43歳時に肛門管癌合併の家族性大腸腺腫症（以下，FAP）に対し大腸全摘・単孔式永久回腸人工肛門造設術が施行された．61歳時には胃腺腫症に対し幽門側胃切除術が施行された．その後，人工肛門からの出血を認めたため近医を受診したところ，人工肛門粘膜に結節病変を指摘された．生検で中分化管状腺癌と診断されたため，当院を紹介され受診した．小腸内視鏡検査，小腸造影検査，体幹CT検査では，人工 …
NAID 130002123536

Birt-Hogg-Dubé Syndrome and Familial Adenomatous Polyposis: An Association or a Coincidence?

Kashiwada Takeru,Shimizu Hidefumi,Tamura Kazuo,Seyama Kuniaki,Horie Yoshimasa,Mizoo Akira
Internal Medicine 51(13), 1789-1792, 2012
… The 60-year-old woman was diagnosed at 28 years of age with colon carcinoma and familial adenomatous polyposis (FAP). … We confirmed the presence of germline mutations in both her folliculin (FLCN) and adenomatous polyposis coli (APC) genes. …
NAID 130002062197