WordNet

to conduct a test or investigation; "We are experimenting with the new drug in order to fight this disease"
the act of conducting a controlled test or investigation (同)experimentation
a venture at something new or different; "as an experiment he decided to grow a beard"
the testing of an idea; "it was an experiment in living"; "not all experimentation is done in laboratories" (同)experimentation
try something new, as in order to gain experience; "Students experiment sexually"; "The composer experimented with a new style" (同)try out
relating to or based on experiment; "experimental physics"
relying on observation or experiment; "experimental results that supported the hypothesis" (同)data-based, observational
of the nature of or undergoing an experiment; "an experimental drug"
nephritis marked by inflammation of the glomeruli of the kidney; characterized by decreased production of urine and by the presence of blood and protein in the urine and by edema

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1. 小児における糸球体腎炎の病因と原因の概要 overview of the pathogenesis and causes of glomerulonephritis in children
2. デンスデポジット病（膜性糸球体腎炎Ⅱ型） dense deposit disease membranoproliferative glomerulonephritis type ii
3. 急速進行性（半月形）糸球体腎炎の分類および治療の概要 overview of the classification and treatment of rapidly progressive crescentic glomerulonephritis
4. 膜性増殖性糸球体腎炎の臨床像、分類、および原因 clinical presentation classification and causes of membranoproliferative glomerulonephritis
5. 膜性増殖性糸球体腎炎の評価および治療 evaluation and treatment of membranoproliferative glomerulonephritis

CX3CR1 Reduces Kidney Fibrosis by Inhibiting Local Proliferation of Profibrotic Macrophages.

Engel DR1, Krause TA2, Snelgrove SL3, Thiebes S2, Hickey MJ3, Boor P4, Kitching AR3, Kurts C5.
Journal of immunology (Baltimore, Md. : 1950).J Immunol.2015 Feb 15;194(4):1628-38. doi: 10.4049/jimmunol.1402149. Epub 2015 Jan 16.
A dense network of macrophages and dendritic cells (DC) expressing the chemokine receptor CX3CR1 populates most tissues. We recently reported that CX3CR1 regulates the abundance of CD11c(+) DC in the kidney and thereby promotes renal inflammation in glomerulonephritis. Given that chronic inflammatio
PMID 25595779

Anti-inflammatory role of DPP-4 inhibitors in a non-diabetic model of glomerular injury.

Higashijima Y1, Tanaka T2, Yamaguchi J3, Tanaka S3, Nangaku M3.
American journal of physiology. Renal physiology.Am J Physiol Renal Physiol.2015 Feb 4:ajprenal.00590.2014. doi: 10.1152/ajprenal.00590.2014. [Epub ahead of print]
Dipeptidyl peptidase-4 (DPP-4) is an enzyme that cleaves and inactivates incretin hormones capable of stimulating insulin secretion from pancreatic β cells. DPP-4 inhibitors are now widely used for the treatment of type 2 diabetes. Experimental studies have suggested a renoprotective role of DPP-4
PMID 25656369

Artemisinin analogue SM934 ameliorates the proteinuria and renal fibrosis in rat experimental membranous nephropathy.

Li TT1, Zhang XH2, Jing JF1, Li X1, Yang XQ1, Zhu FH1, Tang W1, Zuo JP3.
Acta pharmacologica Sinica.Acta Pharmacol Sin.2015 Feb;36(2):188-99. doi: 10.1038/aps.2014.134. Epub 2015 Jan 26.
AIM: SM934 is a novel water-soluble artemisinin derivative with immunoregulatory activities that has been used to treat murine lupus nephritis. In the current study, we investigated the effects of SM934 on rat experimental membranous nephropathy.METHODS: Passive Heymann nephritis (PHN) was induced i
PMID 25619396

敦賀和志,田中完
日本小児腎臓病学会雑誌 26(2), 245-249, 2014
近年，糸球体性腎疾患において病態や病勢を評価する非侵襲的な方法として，尿沈渣細胞中に発現する各種機能分子群の遺伝子発現の検討がなされ，その有用性が報告されている。一方，発現する機能分子群は多種に渡ることから，検討目的とその目的を前提とした候補分子群の絞り込みが課題となる。われわれはこれまで培養ヒトメサンギウム細胞を用いた実験系において，ウイルスの疑似感染を惹起することでToll-like rece …
NAID 130004495416

Long-term observations of clinicopathological characteristics and outcome of Japanese patients with pauci-immune crescentic glomerulonephritis

Kitagawa Kiyoki,Furuichi Kengo,Shinozaki Yasuyuki,Toyama Tadashi,Kitajima Shinji,Hara Akinori,Iwata Yasunori,Sakai Norihiko,Kaneko Shuichi,Wada Takashi
Clinical and Experimental
… Background: The clinicopathological characteristics and outcome with pauci-immune crescentic glomerulonephritis (CreGN) are presumed to vary over time. … when the nationwide survey of rapidly progressive glomerulonephritis [RPGN] was performed in Japan), and Group III (2002-2011, n = 47; …
NAID 120005368212

Primary membranoproliferative glomerulonephritis on the decline : decreased rate from the 1970s to the 2000s in Japan

KAWAMURA Tetsuya,USUI Joichi,KASEDA Koji,TAKADA Kenji,EBIHARA Itaru,ISHIZU Takashi,IITSUKA Tadashi,SAKAI Kentaro,TAKEMURA Katsumi,KOBAYASHI Masaki,KOYAMA Akio,KANEMOTO Katsuyoshi,SUMAZAKI Ryo,UESUGI Noriko,NOGUCHI Masayuki,NAGATA Michio,SUKA Machi,YAMAGATA Kunihiro
Clinical and experimental
NAID 10031169473