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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/07/07 23:38:14」(JST)

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  • Microcosmic mechanism of dication for inhibiting acylation of acidic Peptide.
  • Qi F1, Yang L, Wu J, Ma G, Su Z.
  • Pharmaceutical research.Pharm Res.2015 Jul;32(7):2310-7. doi: 10.1007/s11095-015-1622-5. Epub 2015 Jan 14.
  • PURPOSE: For long-effective peptide formulation based on poly(d,l-lactic-co-glycolic acid) (PLGA) microspheres, acylation often leads to peptide instability during its release and reduced drug efficacy. Among the reported solving strategies, adding dication such as Ca(2+) and Mn(2+) in the formulati
  • PMID 25585955
  • Combination therapy with remote ischemic conditioning and insulin or exenatide enhances infarct size limitation in pigs.
  • Alburquerque-Béjar JJ1, Barba I1, Inserte J1, Miró-Casas E1, Ruiz-Meana M1, Poncelas M1, Vilardosa Ú1, Valls-Lacalle L1, Rodríguez-Sinovas A2, García-Dorado D2.
  • Cardiovascular research.Cardiovasc Res.2015 Jun 4. pii: cvv171. [Epub ahead of print]
  • AIMS: Remote ischemic conditioning (RIC) has been shown to reduce myocardial infarct size in patients. Our objective was to investigate whether the combination of RIC with either exenatide or glucose-insulin-potassium (GIK) is more effective than RIC alone.METHODS AND RESULTS: Pigs were submitted to
  • PMID 26045476
  • GLP-1 Receptor Agonist Exenatide Increases Capillary Perfusion Independent of Nitric Oxide in Healthy Overweight Men.
  • Smits MM1, Muskiet MH2, Tonneijck L2, Kramer MH2, Diamant M2, van Raalte DH2, Serné EH2.
  • Arteriosclerosis, thrombosis, and vascular biology.Arterioscler Thromb Vasc Biol.2015 Jun;35(6):1538-43. doi: 10.1161/ATVBAHA.115.305447. Epub 2015 Apr 23.
  • OBJECTIVE: The insulinotropic gut-derived hormone glucagon-like peptide-1 (GLP-1) increases capillary perfusion via a nitric oxide-dependent mechanism in rodents. This improves skeletal muscle glucose use and cardiac function. In humans, the effect of clinically used GLP-1 receptor agonists (GLP-1RA
  • PMID 25908765


  • GLP-1受容体作動薬 (特集 糖尿病治療薬update : 適正な血糖管理を目指して) -- (糖尿病治療薬の薬効と適応基準)
  • 真下 大和,江藤 一弘
  • 日本臨床 73(3), 433-437, 2015-03
  • NAID 40020367139
  • Case Report : Exenatide Combined with Metformin and Glimepiride Allows Successful Weaning from Insulin in an Obese Diabetic Patient with Klinefelter Syndrome
  • Nagai Yoshio,Nakamura Yuta,Hiroishi Atsushi [他]
  • Journal of St. Marianna University 5(2), 125-129, 2014-12
  • NAID 40020336625
  • 臨床研究・症例報告 小児2型糖尿病に対してエキセナチドを使用した2例の経験
  • 竹本 幸司,秋月 妙子,松本 大輝 [他]
  • 小児科臨床 67(8), 1381-1385, 2014-08
  • NAID 40020126302


Chemistry and pharmacology [edit] Exenatide is a synthetic version of exendin-4, a hormone found in the saliva of the Gila monster that was first isolated by John Eng in 1992 while working at the Veterans Administration Medical ...
2型糖尿病の薬Byetta(バイエッタ、一般名:exenatide)が1型糖尿病のすい島移植にも役に立ちそう! ... HOME | 糖尿病ソリューション | | 2型糖尿病の薬Byetta(バイエッタ、一般名:exenatide)が1型糖尿病のすい島移植にも役に立ち ...