eukaryotic initiation factor-4B

• 真核生物・訳開始因子4B

関

eIF-4B、eIF4B、eukaryotic translation initiation factor 4B

WordNet

1. be a contributing factor; "make things factor into a companys profitability"
2. any of the numbers (or symbols) that form a product when multiplied together
3. an independent variable in statistics
4. anything that contributes causally to a result; "a number of factors determined the outcome"
5. consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
6. resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
7. an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
8. a concept whose truth can be proved; "scientific hypotheses are not facts"
9. a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
10. a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
11. the act of starting something for the first time; introducing something new; "she looked forward to her initiation as an adult"; "the foundation of a new scientific society" (同)founding, foundation, institution, origination, creation, innovation, introduction, instauration
12. a formal entry into an organization or position or office; "his initiation into the club"; "he was ordered to report for induction into the army"; "he gave a speech as part of his installation into the hall of fame" (同)induction, installation
13. having cells with `good or membrane-bound nuclei (同)eucaryotic

PrepTutorEJDIC

1. (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
2. 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
3. 〈U〉開始;創業 / 〈U〉入会,入門;〈C〉入会(入門)式 / 〈U〉手ほどき,伝授

UpToDate Contents

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• 1. 後天性の凝固因子阻害物質 acquired inhibitors of coagulation
• 2. 血友病患者における第VIIIおよび第IX因子阻害物質 factor viii and factor ix inhibitors in patients with hemophilia
• 3. 止血の概要 overview of hemostasis
• 4. 直接トロンビン阻害剤および直接Xa因子阻害剤による抗凝固療法 anticoagulation with direct thrombin inhibitors and direct factor xa inhibitors
• 5. 第ⅩＩ因子欠乏症 factor xi deficiency

English Journal

• Muscarinic acetylcholine receptors mediate eIF4B phosphorylation in SNU-407 colon cancer cells.

• Liu Z1, Cho NJ2.
• Biochemical and biophysical research communications.Biochem Biophys Res Commun.2016 Nov 18;480(3):450-454. doi: 10.1016/j.bbrc.2016.10.069. Epub 2016 Oct 20.
• We have previously shown that muscarinic acetylcholine receptors (mAChRs) promote global protein biosynthesis in SNU-407 colon cancer cells. To gain insight into the molecular mechanisms underlying this event, we examined whether mAChRs regulate the phosphorylation of eIF4B (eukaryotic initiation fa
• PMID 27773818

• Stress granule induction after brain ischemia is independent of eukaryotic translation initiation factor (eIF) 2α phosphorylation and is correlated with a decrease in eIF4B and eIF4E proteins.

• Ayuso MI1, Martínez-Alonso E1, Regidor I1, Alcázar A2.
• The Journal of biological chemistry.J Biol Chem.2016 Nov 11. pii: jbc.M116.738989. [Epub ahead of print]
• Stress granules (SGs) are cytoplasmic ribonucleoprotein aggregates that are directly connected with the translation-initiation arrest response to cellular stresses. Translation inhibition (TI) is observed in transient brain ischemia, condition which induces persistent TI even after reperfusion, i.e.
• PMID 27836976

• eIF4B stimulates translation of long mRNAs with structured 5' UTRs and low closed-loop potential but weak dependence on eIF4G.

• Sen ND1, Zhou F1, Harris MS2, Ingolia NT2, Hinnebusch AG3.
• Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2016 Sep 20;113(38):10464-72. doi: 10.1073/pnas.1612398113. Epub 2016 Sep 6.
• DEAD-box RNA helicases eukaryotic translation initiation factor 4A (eIF4A) and Ded1 promote translation by resolving mRNA secondary structures that impede preinitiation complex (PIC) attachment to mRNA or scanning. Eukaryotic translation initiation factor 4B (eIF4B) is a cofactor for eIF4A but also
• PMID 27601676

Japanese Journal

• Two functionally redundant isoforms of Drosophila melanogaster eukaryotic initiation factor 4B are involved in cap-dependent translation, cell survival, and proliferation

• HERNANDEZ G.
• Eur. J. Biochem. 271, 2923-2936, 2004
• NAID 30014358051

Related Links

• EIF4B - Eukaryotic translation initiation factor 4B - Homo ...

Eukaryotic translation initiation factor 4B Short name: eIF-4B Gene names i Name:EIF4B Organism i Homo sapiens (Human) Taxonomic identifier i 9606 [NCBI] Taxonomic lineage i › Eukaryota› O ...

• Control of Cell Survival and Proliferation by Mammalian ...

Translation initiation plays an important role in cell growth, proliferation, and survival. The translation initiation factor eIF4B (eukaryotic initiation factor 4B) stimulates the RNA helicase activity of eIF4A in unwinding ...

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★リンクテーブル★

リンク元	「eIF4B」「真核生物翻訳開始因子4B」「eukaryotic translation initiation factor 4B」
関連記事	「initiation」「fact」「factor」「eukaryotic」

「eIF4B」

　　[★]

• 真核生物・訳開始因子4B

関

eIF-4B、eukaryotic initiation factor-4B、eukaryotic translation initiation factor 4B

「真核生物翻訳開始因子4B」

　　[★]

英

eukaryotic initiation factor-4B、eukaryotic translation initiation factor 4B、eIF4B、eIF-4B

「eukaryotic translation initiation factor 4B」

　　[★]

• 真核生物・訳開始因子4B

関

eIF-4B、eIF4B、eukaryotic initiation factor-4B

「initiation」

　　[★]

• n.

• 開始、惹起、イニシエーション

関

commence、commencement、evoke、initiate、institute、mount、onset、start

　 　 　

「fact」

　　[★]

• n.

• 事実、現状、実際、実態

関

actual、actually、in fact、in practice、indeed、practically

　 　 　 　 　

「factor」

　　[★]

• n.

• 因子、要因、要素、ファクター

関

element、elementary、factorial、parameter

　 　 　 　 　 　 　

「eukaryotic」

　　[★]

• 真核生物の

関

eucaryote、eukaryote、eukaryotic organism