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the most powerful female hormone that occurs naturally; synthesized and used to treat estrogen deficiency and breast cancer (同)oestradiol

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1. 閉経後のホルモン療法で用いる製剤 preparations for postmenopausal hormone therapy
2. 緊急避妊剤 emergency contraception
3. 化学療法時の大量または不正子宮出血 heavy or irregular uterine bleeding during chemotherapy
4. 重度または持続性子宮出血の管理 managing an episode of severe or prolonged uterine bleeding
5. 小児における非抱合型高ビリルビン血症による黄疸の評価 evaluation of jaundice caused by unconjugated hyperbilirubinemia in children

Regulation of sex steroid production and mRNAs encoding gonadotropin receptors and steroidogenic proteins by gonadotropins, cyclic AMP and insulin-like growth factor-I in ovarian follicles of rainbow trout (Oncorhynchus mykiss) at two stages of vitellogenesis.

Nakamura I1, Kusakabe M1, Swanson P2, Young G3.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.Comp Biochem Physiol A Mol Integr Physiol.2016 Nov;201:132-40. doi: 10.1016/j.cbpa.2016.06.035. Epub 2016 Jul 4.
At the completion of vitellogenesis, the steroid biosynthetic pathway in teleost ovarian follicles switches from estradiol-17β (E2) to maturational progestin production, associated with decreased follicle stimulating hormone (Fsh) and increased luteinizing hormone (Lh) signaling. This study compare
PMID 27387444

Modulatory role of leptin on ovarian functions in water buffalo (Bubalus bubalis).

Reshma R1, Mishra SR1, Thakur N1, Parmar MS1, Somal A1, Bharti MK1, Pandey S1, Chandra V1, Chouhan VS1, Verma MR2, Singh G1, Sharma GT1, Maurya VP1, Sarkar M3.
Theriogenology.Theriogenology.2016 Oct 15;86(7):1720-39. doi: 10.1016/j.theriogenology.2016.05.029. Epub 2016 Jun 2.
The aim of the present study was to demonstrate the modulatory role of leptin on bubaline granulosa cells (GCs) and luteal cells (LCs) functions using an in vitro cell culture system and to establish a cross talk between leptin and insulin-like growth factor-1 (IGF-1). GCs were collected from group
PMID 27381558

Changes in ovarian function associated with circulating concentrations of estradiol before a GnRH-induced ovulation in beef cows.

Larimore EL1, Amundson OL1, Bridges GA2, McNeel AK3, Cushman RA3, Perry GA4.
Domestic animal endocrinology.Domest Anim Endocrinol.2016 Oct;57:71-9. doi: 10.1016/j.domaniend.2016.06.001. Epub 2016 Jun 8.
These studies were conducted to evaluate causes for differences in circulating concentrations of estradiol before a GnRH-induced ovulation. Beef cows were synchronized by an injection of GnRH on day -7 and an injection of prostaglandin F2α (PGF2α) on day 0. In experiment 1, blood samples were coll
PMID 27565233

Nonylphenol disrupts the cardio-protective effects of 17β-estradiol on ischemia/reperfusio injury in isolated hearts of guinea pig

リンク元	「エストラジオール脱水素酵素」「エストラジオールデヒドロゲナーゼ」
関連記事	「dehydrogenase」「dehydrogenases」「estradiol」