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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/01/25 02:37:14」(JST)

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Esthesioneuroblastoma is a rare form of cancer involving nasal cavity and believed to arise from the olfactory epithelium. It can cause loss of vision, and taste.^[1] ^[2] It is often considered synonymous with "olfactory neuroblastoma",^[3] but the tissue of origin is not yet well characterized. Associated with Trisomy 8.

It was first characterized in 1924.^[4]^[5]

Incidence/prevalence

According to the BBC, only 200 cases of the disease have been recorded worldwide in the past two decades.^[6]

A 1997 literature search identified 1,457 cases in the published literature since its discovery in 1924, however 487 were cited in more than one paper, bringing the total of reported cases to 945.^[7]

Treatment

Several surgical approaches have been described,^[8]^[9]^[10]^[11] but post-excision recurrence rates have remained relatively high.

Notable cases

The disease was brought into prominence by the case of Chantal Sébire, who was suffering from the disease and ended her life after being denied euthanasia.^[12]

References

^ Sharma S, Sharma MC, Johnson MH, Lou M, Thakar A, Sarkar C (2007). "Esthesioneuroblastoma - a clinicopathologic study and role of DNA topoisomerase alpha" (^{[dead link]} – ^{Scholar search}). Pathol. Oncol. Res. 13 (2): 123–9. doi:10.1007/BF02893487. PMID 17607373.
^ http://www.brisbanetimes.com.au/articles/2008/03/18/1205602424048.html
^ "Medcyclopaedia - Esthesioneuroblastoma". Archived from the original on 2012-02-05. Retrieved 2008-03-22.
^ "Esthesioneuroblastoma". Retrieved 2008-03-22. ^{[dead link]}
^ Berger L, Luc G, Richard D. L'esthésioneuroépithéliome olfactif. Bull Assoc Franç Étude Cancer 1924;13:410-421.
^ "Tumour woman's death not natural". BBC News. 2008-03-21. Retrieved 2008-03-22.
^ Broich G, Pagliari A, Ottaviani F (1997). "Esthesioneuroblastoma: a general review of the cases published since the discovery of the tumour in 1924". Anticancer Res. 17 (4A): 2683–706. PMID 9252701.
^ Vergani F, Pirola E, Fiori L, Pagni F, Parmigiani F, Sganzerla EP (2007). "Combined transcranial and endoscopic nasal resection for esthesioneuroblastoma. Technical note". J Neurosurg Sci 51 (2): 99–102. PMID 17571044.
^ Unger F, Walch C, Stammberger H, Papaefthymiou G, Haselsberger K, Pendl G (2001). "Olfactory neuroblastoma (esthesioneuroblastoma): report of six cases treated by a novel combination of endoscopic surgery and radiosurgery". Minim Invasive Neurosurg 44 (2): 79–84. doi:10.1055/s-2001-16000. PMID 11487789.
^ Cakmak O, Ergin NT, Yilmazer C, Kayaselçuk F, Barutcu O (2002). "Endoscopic removal of esthesioneuroblastoma". Int. J. Pediatr. Otorhinolaryngol. 64 (3): 233–8. doi:10.1016/S0165-5876(02)00036-8. PMID 12090952.
^ Prasad KC, Kumar A, Prasad SC, Jain D (2007). "Endoscopic-assisted excision of esthesioneuroblastoma". J Craniofac Surg 18 (5): 1034–8. doi:10.1097/scs.0b013e318157264c. PMID 17912077.
^ Tumour woman's death not natural BBC 21 March 2008

UpToDate Contents

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1. 嗅神経芽細胞腫（鼻腔神経芽細胞腫） olfactory neuroblastoma esthesioneuroblastoma
2. 鼻腔の腫瘍 tumors of the nasal cavity
3. 副鼻腔癌 paranasal sinus cancer
4. 頭頸部腫瘍の病理 pathology of head and neck neoplasms
5. 神経芽細胞腫の臨床所見、診断、および病期分類評価 clinical presentation diagnosis and staging evaluation of neuroblastoma

English Journal

Esthesioneuroblastoma: a contemporary review of diagnosis and management.

Bak M, Wein RO.SourceEastern Virginia Medical School, 600 Gresham Drive Suite 1100, Norfolk, VA 23507, USA.
Hematology/oncology clinics of North America.Hematol Oncol Clin North Am.2012 Dec;26(6):1185-207. doi: 10.1016/j.hoc.2012.08.005. Epub 2012 Sep 29.
Esthesioneuroblastoma (ENB) is a rare malignancy, representing only 3% to 6% of all sinonasal malignancies. A wide array of treatment options for ENB have been described in the literature, but prospective clinical trials are absent given the tumor's rarity and natural history. Delay in diagnosis lea
PMID 23116576

Japanese Journal

嗅神経芽細胞腫に対する内視鏡下経鼻手術―その術式の検討

日本鼻科学会会誌 51(4), 474-480, 2012
NAID 130004891742

原発性トルコ鞍部神経芽腫の1例

脳神経外科ジャーナル 20(11), 833-840, 2011-11-20
NAID 110008762365

Related Pictures

★リンクテーブル★

リンク元	「感覚神経芽細胞腫」
拡張検索	「olfactory esthesioneuroblastoma」

「感覚神経芽細胞腫」

Esthesioneuroblastoma
	Esthesioneuroblastoma
Classification and external resources
ICD-10	C30.0
ICD-9	160.0
ICD-O:	M9522/3
OMIM	133450
DiseasesDB	32047
eMedicine	med/748
MeSH	D018304

　　[★]

英: esthesioneuroblastoma
関: 嗅神経芽細胞腫

「olfactory esthesioneuroblastoma」

　　[★]

嗅粘膜上皮に発生する悪性腫瘍

嗅神経芽腫、嗅神経芽細胞腫

関: esthesioneuroblastoma

[pmid17607373-1] Sharma S, Sharma MC, Johnson MH, Lou M, Thakar A, Sarkar C (2007). "Esthesioneuroblastoma - a clinicopathologic study and role of DNA topoisomerase alpha" (^{[dead link]} – ^{Scholar search}). Pathol. Oncol. Res. 13 (2): 123–9. doi:10.1007/BF02893487. PMID 17607373.

[2] ttp://www.brisbanetimes.com.au/articles/2008/03/18/1205602424048.html

[3] "Medcyclopaedia - Esthesioneuroblastoma". Archived from the original on 2012-02-05. Retrieved 2008-03-22.

[titleEsthesioneuroblastoma-4] "Esthesioneuroblastoma". Retrieved 2008-03-22. ^{[dead link]}

[5] Berger L, Luc G, Richard D. L'esthésioneuroépithéliome olfactif. Bull Assoc Franç Étude Cancer 1924;13:410-421.

[titleBBC_NEWS_.7C_Europe_.7C_Tumour_womans_death_not_natural-6] "Tumour woman's death not natural". BBC News. 2008-03-21. Retrieved 2008-03-22.

[pmid9252701-7] Broich G, Pagliari A, Ottaviani F (1997). "Esthesioneuroblastoma: a general review of the cases published since the discovery of the tumour in 1924". Anticancer Res. 17 (4A): 2683–706. PMID 9252701.

[pmid17571044-8] Vergani F, Pirola E, Fiori L, Pagni F, Parmigiani F, Sganzerla EP (2007). "Combined transcranial and endoscopic nasal resection for esthesioneuroblastoma. Technical note". J Neurosurg Sci 51 (2): 99–102. PMID 17571044.

[pmid11487789-9] Unger F, Walch C, Stammberger H, Papaefthymiou G, Haselsberger K, Pendl G (2001). "Olfactory neuroblastoma (esthesioneuroblastoma): report of six cases treated by a novel combination of endoscopic surgery and radiosurgery". Minim Invasive Neurosurg 44 (2): 79–84. doi:10.1055/s-2001-16000. PMID 11487789.

[pmid12090952-10] Cakmak O, Ergin NT, Yilmazer C, Kayaselçuk F, Barutcu O (2002). "Endoscopic removal of esthesioneuroblastoma". Int. J. Pediatr. Otorhinolaryngol. 64 (3): 233–8. doi:10.1016/S0165-5876(02)00036-8. PMID 12090952.

[pmid17912077-11] Prasad KC, Kumar A, Prasad SC, Jain D (2007). "Endoscopic-assisted excision of esthesioneuroblastoma". J Craniofac Surg 18 (5): 1034–8. doi:10.1097/scs.0b013e318157264c. PMID 17912077.

[12] Tumour woman's death not natural BBC 21 March 2008

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案内

esthesioneuroblastoma