WordNet

a missing piece (as a gap in a manuscript)
rupture in smooth muscle tissue through which a bodily structure protrudes (同)herniation
relating to the esophagus

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《文》すきま,割れ目 / 欠文,脱字 / 《文》(時間などの)中絶,とぎれ
ヘルニア,脱腸

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1. 裂孔ヘルニア hiatus hernia
2. 傍食道ヘルニア：臨床的特徴および外科的修復 paraesophageal hernia clinical features and surgical repair
3. 高解像度食道内圧検査 high resolution manometry
4. 逆流性食道炎の病態生理 pathophysiology of reflux esophagitis
5. 良性食道狭窄のマネージメント management of benign esophageal strictures

English Journal

Pathophysiology of Gastroesophageal Reflux Disease.

Boeckxstaens GE1, Rohof WO2.Author information 1Department of Gastroenterology, Translational Research Center for Gastrointestinal Disorders (TARGID), University Hospital of Leuven, University of Leuven, Herestraat 49, Leuven 3000, Belgium. Electronic address: guy.boeckxstaens@med.kuleuven.be.2Department of Gastroenterology and Hepatology, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.AbstractGastroesophageal reflux disease (GERD) is one of the most common digestive diseases in the Western world, with typical symptoms, such as heartburn, regurgitation, or retrosternal pain, reported by 15% to 20% of the general population. The pathophysiology of GERD is multifactorial. Our understanding of these factors has significantly improved in recent years, with increased understanding of the acid pocket and hiatal hernia and how these factors interact. Although our insight has significantly increased over the past years, more studies are required to better understand symptom generation in GERD, especially in patients with therapy-resistant symptoms.
Gastroenterology clinics of North America.Gastroenterol Clin North Am.2014 Mar;43(1):15-25. doi: 10.1016/j.gtc.2013.11.001. Epub 2013 Dec 27.
Gastroesophageal reflux disease (GERD) is one of the most common digestive diseases in the Western world, with typical symptoms, such as heartburn, regurgitation, or retrosternal pain, reported by 15% to 20% of the general population. The pathophysiology of GERD is multifactorial. Our understanding
PMID 24503356

Esophageal pressure topography, body position, and hiatal hernia.

Hashmi S, Rao SS, Summers RW, Schulze K.Author information *University of Iowa Carver College of Medicine and VAMC, Iowa City, IA †Medical College of Georgia, Georgia Regents University, Augusta, GA.AbstractINTRODUCTION: Whether body position affects lower esophageal sphincter (LES) function and detection of hiatal hernia is unknown. Moreover, the yield of high-resolution esophageal pressure topography (HREPT) when compared with endoscopy for detection of hiatal hernia is unclear.
Journal of clinical gastroenterology.J Clin Gastroenterol.2014 Mar;48(3):224-30. doi: 10.1097/MCG.0000000000000057.
INTRODUCTION: Whether body position affects lower esophageal sphincter (LES) function and detection of hiatal hernia is unknown. Moreover, the yield of high-resolution esophageal pressure topography (HREPT) when compared with endoscopy for detection of hiatal hernia is unclear.AIM: : The aims of thi
PMID 24440930

Hiatal hernia repair in laparoscopic adjustable gastric banding and laparoscopic roux-en-y gastric bypass: a national database analysis.

Al-Haddad BJ, Dorman RB, Rasmus NF, Kim YY, Ikramuddin S, Leslie DB.Author information Department of Surgery, 420 Delaware St. SE, MMC 290, Minneapolis, MN, 55455, USA.AbstractHiatal hernia (HH) repairs are commonly done concomitantly with laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic adjustable gastric banding (LAGB) to decrease gastroesophageal reflux disease (GERD). There is limited evidence about the additional surgical risk these combined procedures engender. We used the United States Nationwide Inpatient Sample 2004-2009 to compare mortality risk, prolonged length of stay (PLOS), and perioperative adverse events using propensity score-matched analysis. We repeated the analysis after removing patients diagnosed with GERD. There were 42,272 weighted patients undergoing LRYGB alone representing 206,559 discharges nationally and an additional 1,945 and 9,060, respectively, undergoing LRYGB + HH repair. For LAGB, there were 10,558 records representing 52,901 LAGB-only discharges and 1,959 representing 9,893 LAGB + HH repair discharges. Thirty-eight percent (95 % CI: 36, 41 %) of the patients in the LRYGB-only group had GERD compared to 55 % (51, 59 %) in the LRYGB + HH repair group. Among the LAGB groups, 31 % (28, 34 %) of LAGB-only patients had GERD compared to 44 % (38, 49 %) in the LAGB + HH repair group. We find that the average treatment effect on the treated (considering the concomitant procedure as treatment and the single procedure as control) for PLOS was -0.12353 (-0.15909, -0.08797) between the LRYGB groups and -0.04353 (-0.07488, -0.01217) for the LAGB groups. We find no evidence of increased risk of perioperative adverse events among patients undergoing concomitant HH repair with LRYGB or LAGB. Patients undergoing the combined procedure appear to be at lower risk of PLOS; this may be due to surgical training norms.
Obesity surgery.Obes Surg.2014 Mar;24(3):377-84. doi: 10.1007/s11695-013-1106-9.
Hiatal hernia (HH) repairs are commonly done concomitantly with laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic adjustable gastric banding (LAGB) to decrease gastroesophageal reflux disease (GERD). There is limited evidence about the additional surgical risk these combined procedures
PMID 24307434

Japanese Journal

症例胸腔鏡・腹腔鏡下食道切除後の横隔膜ヘルニアを腹腔鏡下に修復した1例

山浦忠能,金谷誠一郎,細木久裕 [他]
外科 = Surgey : 臨床雑誌 76(11), 1298-1301, 2014-11
NAID 40020245428

特発性横隔膜破裂の1例

増田隆洋,矢野文章,秋元俊亮,坪井一人,小村伸朗,矢永勝彦
日本臨床外科学会雑誌 75(9), 2457-2461, 2014
症例は24歳，男性．2012年10月初旬，自転車運転中に突然左胸痛が出現し，近医を受診した．胸部単純X線検査にて左横隔膜の挙上を認め，精査加療目的にて同日入院となった．胸腹部CTにて左横隔膜と胃の挙上を認め，横隔膜弛緩症の診断にて胸腔鏡下に修復術を試みられたが，胃・大網・横行結腸・脾が左胸腔内に脱出しており，特発性横隔膜破裂と診断された．胸腔鏡下での修復は困難と判断され，観察のみで手術を終了した． …
NAID 130005063150

服薬アドヒアランス不良による再発性Barrett潰瘍の1例

宮原庸介,川辺晃一,葛西豊高,福田裕昭,村松誠司,山田拓郎,山田千寿,釜田茂幸,藤田昌久,新田宙,石川文彦,伊藤博
Progress of Digestive Endoscopy 85(1), 64-65, 2014
… Esophagogastroduodenoscopy revealed hiatus hernia, Barrett's esophagus and multiple esophageal ulcers. …
NAID 130004985563