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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/04/09 09:52:32」(JST)

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  • Functional assay of antiplatelet drugs based on margination of platelets in flowing blood.
  • Eichinger CD1, Fogelson AL2, Hlady V1.
  • Biointerphases.Biointerphases.2016 Jun 30;11(2):029805. doi: 10.1116/1.4945305.
  • A novel functional assay of antiplatelet drug efficacy was designed by utilizing the phenomena of platelet margination in flowing blood and transient platelet contacts with surface-immobilized platelet agonists. Flow margination enhances transient contacts of platelets with the walls of flow chamber
  • PMID 27030476
  • The Platelet Integrin αIIbβ3 Differentially Interacts with Fibrin Versus Fibrinogen.
  • Litvinov RI1, Farrell DH2, Weisel JW1, Bennett JS3.
  • The Journal of biological chemistry.J Biol Chem.2016 Apr 8;291(15):7858-67. doi: 10.1074/jbc.M115.706861. Epub 2016 Feb 10.
  • Fibrinogen binding to the integrin αIIbβ3 mediates platelet aggregation and spreading on fibrinogen-coated surfaces. However,in vivoαIIbβ3 activation and fibrinogen conversion to fibrin occur simultaneously, although the relative contributions of fibrinogenversusfibrin to αIIbβ3-mediated plate
  • PMID 26867579
  • Comparison between the Outcomes of Intracoronary and Intravenous Administration of Eptifibatide during Primary Percutaneous Coronary Intervention in Patients with Acute ST-Elevation Myocardial Infarction.
  • Esfandi A1, Fotouhi M, Allami A, Ebrahimi M.
  • Journal of atherosclerosis and thrombosis.J Atheroscler Thromb.2016 Apr 1;23(4):465-76. doi: 10.5551/jat.30965. Epub 2015 Dec 2.
  • AIM: To compare the outcomes of intracoronary (IC) and intravenous (IV) administration of eptifibatide during primary percutaneous coronary intervention (PPCI) in patients with ST-elevation myocardial infarction (STEMI).METHODS: In this prospective double-blind randomized clinical trial, 76 patients
  • PMID 26632161


  • Improved liquid chromatography-tandem mass spectrometry method for the analysis of eptifibatide in human plasma
  • ZHOU Zhi-Ling,YU Xi-Yong,YANG Min,MAI Li-Ping,LIN Qiu-Xiong,DENG Chun-Yu,SHAN Zhi-Xin,KUANG Su-Juan,ZHU Ping,HUANG Xiao-Zhong,LI Xiao-Hong,CHEN Tie-Feng,LIN Shu-Guang
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 878(23), 2094-2100, 2010-08-01
  • NAID 10028039745
  • Upstream vs Deferred Administration of Small-Molecule Glycoprotein IIb/IIIa Inhibitors in Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction : Insights From Randomized Clinical Trials
  • DONG Lili,ZHANG Feng,SHU Xianhong
  • Circulation journal : official journal of the Japanese Circulation Society 74(8), 1617-1624, 2010-07-25
  • Background: Recent data have demonstrated similar outcomes for patients with ST-segment elevation myocardial infarction (STEMI) who undergo primary percutaneous coronary intervention (PCI) and are tre …
  • NAID 10026565709
  • Determination of eptifibatide concentration in human plasma utilizing the liquid chromatography-tandem mass spectrometry method
  • LIU Jia,DUAN Xiaotao,CHEN Xiaoyan,ZHONG Dafang
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 877(5), 527-532, 2009-02-15
  • NAID 10028013323


Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class. [1] Eptifibatide is a cyclic heptapeptide derived from a protein found in ...
eptifibatide /ep·ti·fib·a·tide/ (ep″tĭ-fib´ah-tīd) an inhibitor of platelet aggregation used for the prevention of thrombosis in patients with acute coronary syndrome or undergoing certain percutaneous coronary procedures. eptifibatide, an ...