epidural tumor

WordNet

1. an abnormal new mass of tissue that serves no purpose (同)tumour, neoplasm
2. on or outside the dura mater (同)extradural

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/11/26 11:57:34」(JST)

wiki en

[Wiki en表示]

Spinal tumors
Classification and external resources
ICD-10	C72.0
ICD-9	192.2
DiseasesDB	31483
MedlinePlus	001403
eMedicine	orthoped/49 med/2993, radio/169
MeSH	C04.557.465.220

Spinal tumors are neoplasms located in the spinal cord. Extradural tumors are more common than intradural neoplasms.

Depending on their location, the spinal cord tumors can be:

• Extradural - outside the dura mater lining (most common)
• Intradural - part of the dura
  • Intramedullary - inside the spinal cord
  • Extramedullary- inside the dura, but outside the spinal cord

Pathology

Extradural tumors are mostly metastases from primary cancers elsewhere (commonly breast, prostate and lung cancer). Primary tumors may be benign (e.g. hemangioma) or malignant in nature.

Symptoms

The symptoms seen are due to spinal nerve compression and weakening of the vertebral structure. Incontinence and decreased sensitivity in the saddle area (buttocks) are generally considered warning signs of spinal cord compression by the tumor. Other symptoms of spinal cord compression include lower extremity weakness, sensory loss, and rapid onset paralysis. The diagnosis of primary spinal cord tumors is very difficult, mainly due to its symptoms, which tend to be wrongly attributed to more common and benign degenerative spinal diseases.

Spinal cord compression is commonly found in patients with metastatic malignancy. Back pain is a primary symptom of spinal cord compression in patients with known malignancy. It may prompt a bone scan to confirm or exclude spinal metastasis. Rapid identification and intervention of malignant spinal tumors, often causing spinal cord compression, is key to maintaining quality of life in patients.

Diagnosis

The diagnosis of primary spinal cord tumors is difficult, mainly due to their symptoms, which in early stages mimic more common and benign degenerative spinal diseases. MRI and bone scanning are used for diagnostic purposes. This assesses not only the location of the tumor(s) but also their relationship with the spinal cord and the risk of cord compression.

Treatment

• Steroids (e.g. corticosteroids) may be administered if there is evidence of spinal cord compression. These do not affect the tumoral mass itself, but tend to reduce the inflammatory reaction around it, and thus decrease the overall volume of the mass impinging on the spinal cord.
• Radiotherapy may be administered to patients with malignant tumors. Radiation is usually delivered to the involved segment in the spinal cord as well as to the uninvolved segment above and below the involved segment.
• Surgery is sometimes possible. The goals of surgical treatment for spinal tumors can include histologic diagnosis, tumor local control or oncological cure, pain relief, spinal cord decompression and restoration of neurological function, restoration of spine stability, and deformity rectification.
• The combination of Minimally Invasive Surgery and Radiation or Chemotherapy is a new, minimally invasive technique, pioneered at Mount Sinai Hospital, New York by Dr. Arthur Jenkins *[1] This treatment can be tailored to the particular tumor of the spine, either metastatic or primary. [2]

Some suggest that direct decompressive surgery combined with postoperative radiotherapy provide better outcomes than treatment with radiotherapy alone for patients with spinal cord compression due to metastatic cancer. It is also important to take into consideration the prognosis of the patients and their ambulation status at diagnosis, and treat accordingly.

References

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 脊髄腫瘍 spinal cord tumors
• 2. 馬尾症候群などの腫瘍による硬膜外脊髄圧迫の臨床的特徴および診断 clinical features and diagnosis of neoplastic epidural spinal cord compression including cauda equina syndrome
• 3. 小児における後天性斜頚 acquired torticollis in children
• 4. 転移性の胃腸膵管系神経内分泌腫瘍：腫瘍増殖およびホルモン過剰分泌による症状を管理するための局所治療の選択肢 metastatic gastroenteropancreatic neuroendocrine tumors local options to control tumor growth and symptoms of hormone hypersecretion
• 5. 硬膜内神経鞘腫 intradural nerve sheath tumors

English Journal

• Tumor pseudoprogression of spinal metastasis after radiosurgery: a novel concept and case reports.

• Taylor DR1, Weaver JA.
• Journal of neurosurgery. Spine.J Neurosurg Spine.2015 Feb 6:1-6. [Epub ahead of print]
• Radiosurgery for primary and metastatic tumors of the central nervous system is increasing in utility and intensity. Known complications in the brain include radiation necrosis and the well-documented phenomenon of pseudoprogression. Known complications of radiosurgery to spinal column tumors includ
• PMID 25658469

• En bloc spondylectomy for primary malignant fibrous histiocytoma of the thoracic spine with aortic involvement: case report.

• Somasundaram A1, Wicks RT, Lata AL, Qasem SA, Hsu W.
• Journal of neurosurgery. Spine.J Neurosurg Spine.2015 Feb 6:1-7. [Epub ahead of print]
• In this article, the authors describe a 48-year-old man who initially presented with progressively worsening back pain. Magnetic resonance imaging revealed a soft-tissue mass involving the T10-11 vertebral bodies with extension anteriorly into the aorta as well as epidural extension without spinal c
• PMID 25658464

Japanese Journal

• 臨床室 突然の対麻痺で発症した精巣原発の転移性脊椎腫瘍の1例

• 亀井 克彦,関 庄二,牧野 紘士 [他]
• 整形外科 = Orthopedic surgery 65(6), 529-532, 2014-06
• NAID 40020104689

• Chronic Spontaneous Lumbar Epidural Hematoma Simulating Extradural Spinal Tumor : A Case Report

• MATSUI HIROKI,ISHIGURO NAOKI,MATSUMOTO TOMOHIRO,MURAMOTO AKIO,TAUCHI RYOJI,HIRANO KENICHI,ANDO KEI,ITO ZENYA,IMAGAMA SHIRO
• Nagoya Journal of Medical Science 76(1-2), 195-201, 2014-02
• NAID 120005385264

Related Links

• Epidural Tumor - YouTube

Medical Animations by High Impact Graphics. Learn more at HighImpact.com or give us a call at 800-749-2184. ... 17:36 T5 Meningioma Resection by Kavian Shahi MD PhD 1,203 views 14:59 Dissection: Vertebral ...

• Epidural tumor | MEDtube.net

The author of this video presents epidural tumor. Medical Animations by High Impact Graphics. Learn more at HighImpact.com or give us a call at 800-749-2184. ... Are you Health Professional? Register, join MEDtube for unlimited ...

Related Pictures

---

★リンクテーブル★

リンク元	「硬膜外腫瘍」「epidural neoplasm」
関連記事	「epidural」「tumor」

「硬膜外腫瘍」

　　[★]

英

epidural tumor、extradural tumors

同

硬膜外脊髄腫瘍 extradural spinal tumor

「epidural neoplasm」

　　[★]

硬膜外腫瘍、硬膜外新生物

関

epidural tumor

「epidural」

　　[★]

• 硬膜外の

関

extradural、extradurally

　

「tumor」

　　[★]

• n.

• 腫瘍、腫瘤、腫脹