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abnormal increase in number of cells

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/10/26 16:32:42」(JST)

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Acanthosis is diffuse epidermal hyperplasia (thickening of the skin).^[1] It implies increased thickness of the Malpighian layer (stratum basale and stratum spinosum).^[2]

References

^ Kumar, Vinay; Fausto, Nelso; Abbas, Abul (2004) Robbins & Cotran Pathologic Basis of Disease (7th ed.). Saunders. Page 1230. ISBN 0-7216-0187-1.
^ M. S. Stone; T. L. Ray (September 1995). "Acanthosis". DermPathTutor. Department of Dermatology, University of Iowa. Retrieved 17 May 2012.

UpToDate Contents

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1. 表皮母斑および表皮母斑症候群 epidermal nevus and epidermal nevus syndrome
2. カウデン症候群などのPTEN過誤腫症候群 pten hamartoma tumor syndrome including cowden syndrome
3. 思春期における多嚢胞性卵巣症候群の診断的評価 diagnostic evaluation of polycystic ovary syndrome in adolescents
4. Uncommon congenital adrenal hyperplasias
5. 好酸球の生物学および好酸球増多症の原因 eosinophil biology and causes of eosinophilia

English Journal

Inducible expression of transgenic human TNFα in adult mice develops psoriatic-like arthritis.

Retser E, Schied T, Skryabin BV, Vogl T, Kanczler JM, Hamann N, Niehoff A, Hermann S, Eisenblätter M, Wachsmuth L, Pap T, van Lent P, Loser K, Roth J, Zaucke F, Ludwig S, Wixler V.SourceInstitute of Molecular Virology, ZMBE, University Hospital Muenster, 48149, Muenster, Germany.
Arthritis and rheumatism.Arthritis Rheum.2013 Jun 5. doi: 10.1002/art.38026. [Epub ahead of print]
Objective: Generation of inducible TNFα transgenic mice to overcome a major disadvantage of existing transgenic mice with constitutive expression of TNFα: the limitation in crossing them with various knockout or transgenic mice. Methods: A transgenic mouse line that expresses the human TNFα cytok
PMID 23740547

Acute mucocutaneous methotrexate toxicity associated with interface dermatitis and numerous eosinophils.

Ferguson NN, Asarch A, Vanbeek M, Swick BL.SourceDepartment of Dermatology, University of Iowa Hospital and Clinics, Iowa City, IA.
The American Journal of dermatopathology.Am J Dermatopathol.2013 Jun;35(4):e63-6. doi: 10.1097/DAD.0b013e31827b7674.
: Acute mucocutaneous methotrexate toxicity is not classically associated with prominent tissue eosinophilia. We present a case of acute methotrexate toxicity associated with pancytopenia and mucocutaneous erosion with interface dermatitis and numerous eosinophils. A 79-year-old male, with a history
PMID 23221488