epidermal growth factor receptor

出典: meddic

上皮成長因子受容体 EGFR

EGFR

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/12/01 12:14:18」(JST)

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英文文献

  • Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer: A new era begins.
  • Remon J, Morán T, Majem M, Reguart N, Dalmau E, Márquez-Medina D, Lianes P.SourceMedical Oncology Department, Hospital de Mataró, Carretera de la Cirera, s/n, 08304 Mataró, Barcelona, Spain. Electronic address: jremon@csdm.cat.
  • Cancer treatment reviews.Cancer Treat Rev.2014 Feb;40(1):93-101. doi: 10.1016/j.ctrv.2013.06.002. Epub 2013 Jul 3.
  • The discovery of mutated oncogenes has opened up a new era for the development of more effective treatments for non-small cell lung cancer patients (NSCLC) harbouring EGFR mutations. However, patients with EGFR-activating mutation ultimately develop acquired resistance (AR). Several studies have ide
  • PMID 23829935
  • Surface plasmon resonance spectroscopy for characterisation of membrane protein-ligand interactions and its potential for drug discovery.
  • Patching SG.SourceSchool of Biomedical Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, UK. Electronic address: s.g.patching@leeds.ac.uk.
  • Biochimica et biophysica acta.Biochim Biophys Acta.2014 Jan;1838(1):43-55. doi: 10.1016/j.bbamem.2013.04.028. Epub 2013 May 9.
  • Surface plasmon resonance (SPR) spectroscopy is a rapidly developing technique for the study of ligand binding interactions with membrane proteins, which are the major molecular targets for validated drugs and for current and foreseeable drug discovery. SPR is label-free and capable of measuring rea
  • PMID 23665295
  • Blockage of a miR-21/EGFR regulatory feedback loop augments anti-EGFR therapy in glioblastomas.
  • Zhang KL, Han L, Chen LY, Shi ZD, Yang M, Ren Y, Chen LC, Zhang JX, Pu PY, Kang CS.SourceDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin 300052, China; Laboratory of Neuro-Oncology, Tianjin Neurological Institute, Tianjin 300052, China; Key Laboratory of Post-trauma Neuro-repair and Regeneration in Central Nervous System, Ministry of Education, Tianjin 300052, China; Tianjin Key Laboratory of Injuries, Variations and Regeneration of Nervous System, Tianjin 300052, China; Chinese Glioma Cooperative Group (CGCG), China.
  • Cancer letters.Cancer Lett.2014 Jan 1;342(1):139-49. doi: 10.1016/j.canlet.2013.08.043. Epub 2013 Sep 3.
  • Epidermal growth factor receptors (EGFR) expression is frequently amplified in human glioblastoma cells. Nimotuzumab, a monoclonal antibody (mAb) against EGFR, has been used globally in clinics as an anti-cancer agent. It is largely unknown whether the blockade of miR-21, a microRNA that is upregula
  • PMID 24012640

和文文献

  • Efficacy of increased-dose erlotinib for central nervous system metastases in non-small cell lung cancer patients with epidermal growth factor receptor mutation.
  • Togashi Yosuke,Masago Katsuhiro,Fukudo Masahide,Tsuchido Yasuhiro,Okuda Chiyuki,Kim Young Hak,Ikemi Yasuaki,Sakamori Yuichi,Mio Tadashi,Katsura Toshiya,Mishima Michiaki
  • Cancer chemotherapy and pharmacology 68(4), 1089-1092, 2011-10
  • Recent reports indicate that refractory central nervous system (CNS) metastases of non-small cell lung cancer (NSCLC) are improved by high-dose gefitinib or erlotinib administration. We describe a Jap …
  • NAID 120003534363
  • The Influence of Intracellular Epidermal Growth Factor Receptor (EGFR) Signal Activation on the Outcome of EGFR Tyrosine Kinase Inhibitor Treatment for Pulmonary Adenocarcinoma
  • KAWANO DAIGO,YANO TOKUJIRO,SHOJI FUMIHIRO,ITO KENSAKU,MORODOMI YOSUKE,HARO AKIRA,MIURA NAOKO,TAKENAKA TOMOYOSHI,YOSHINO ICHIRO,MAEHARA YOSHIHIKO
  • Surgery today : the Japanese journal of surgery 41(6), 818-823, 2011-06-01
  • NAID 10029048108

関連リンク

The official name of this gene is “epidermal growth factor receptor.” EGFR is the gene's official symbol. The EGFR gene is also known by other names, listed below. Read more about gene names and symbols on the About ...
131550 - EPIDERMAL GROWTH FACTOR RECEPTOR; EGFR - V-ERB-B AVIAN ERYTHROBLASTIC LEUKEMIA VIRAL ONCOGENE HOMOLOG;; ONCOGENE ERBB;; ERBB1;; HER1;; SPECIES ANTIGEN 7 ... ...

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★リンクテーブル★
リンク元上皮成長因子受容体」「上皮成長因子レセプター」「EGF receptor」「上皮増殖因子レセプター」「EGFR
拡張検索epidermal growth factor receptor gene」「epidermal growth factor receptor kinase」「human epidermal growth factor receptor 2
関連記事grow」「growth」「factor」「fact」「receptor

上皮成長因子受容体」

  [★]

epidermal growth factor receptorEGF receptorEGFR
上皮成長因子レセプターEGFレセプターEGF受容体上皮成長因子受容体キナーゼ上皮増殖因子レセプター上皮増殖因子受容体


上皮成長因子レセプター」

  [★]

epidermal growth factor receptorEGF receptor
上皮成長因子受容体EGFレセプターEGF受容体上皮増殖因子レセプター上皮増殖因子受容体


EGF receptor」

  [★]

EGFRepidermal growth factor receptorepidermal growth factor receptor kinase

上皮増殖因子レセプター」

  [★]

epidermal growth factor receptor
上皮成長因子受容体上皮成長因子レセプター上皮成長因子受容体キナーゼ上皮増殖因子受容体


EGFR」

  [★]


epidermal growth factor receptor gene」

  [★]

EGFR gene


epidermal growth factor receptor kinase」

  [★]

EGF receptorepidermal growth factor receptor


human epidermal growth factor receptor 2」

  [★]

HER2


grow」

  [★]

  • v.
(過去: grew-過去分詞: grown)
extendgrowthoutgrowoutgrowthstretch

WordNet   license wordnet

「cultivate by growing, often involving improvements by means of agricultural techniques; "The Bordeaux region produces great red wines"; "They produce good ham in Parma"; "We grow wheat here"; "We raise hogs here"」
raise, farm, produce

WordNet   license wordnet

「come to have or undergo a change of (physical features and attributes); "He grew a beard"; "The patient developed abdominal pains"; "I got funny spots all over my body"; "Well-developed breasts"」
develop, produce, get, acquire

WordNet   license wordnet

「become attached by or as if by the process of growth; "The tree trunks had grown together"」

WordNet   license wordnet

「become larger, greater, or bigger; expand or gain; "The problem grew too large for me"; "Her business grew fast"」

WordNet   license wordnet

「cause to grow or develop; "He grows vegetables in his backyard"」

WordNet   license wordnet

「increase in size by natural process; "Corn doesn''t grow here"; "In these forests, mushrooms grow under the trees"; "her hair doesn''t grow much anymore"」

PrepTutorEJDIC   license prepejdic

「『成長する』,育つ,〈植物が〉生える,茂る / (類・量・程などにおいて)『増大する』,大きくなる / 『しだいになる』 / …‘を'成長させる,大きくする,育てる / …から生じる(起こる)」

growth」

  [★]

  • n.
  • 成長


WordNet   license wordnet

「(biology) the process of an individual organism growing organically; a purely biological unfolding of events involved in an organism changing gradually from a simple to a more complex level; "he proposed an indicator of osseous development in children"」
growing, maturation, development, ontogeny, ontogenesis

WordNet   license wordnet

「(pathology) an abnormal proliferation of tissue (as in a tumor)」

WordNet   license wordnet

「a progression from simpler to more complex forms; "the growth of culture"」

WordNet   license wordnet

「something grown or growing; "a growth of hair"」

WordNet   license wordnet

「vegetation that has grown; "a growth of trees"; "the only growth was some salt grass"」

PrepTutorEJDIC   license prepejdic

「〈U〉(…の)『成長』,発育;『発達』,発展《+『of』+『名』》 / 〈U〉(数・量,重要性・力などの)『増加』,増大,拡張《+『of』+『名』》 / 〈U〉《修飾語[句]を伴って》栽培,生産,…産 / 〈C〉成育した物,(草,木,髪,ひげなどの)生えたもの / 〈C〉腫瘍(しゅよう)」


factor」

  [★]

  • n.
elementelementaryfactorialparameter

WordNet   license wordnet

「be a contributing factor; "make things factor into a company''s profitability"」

WordNet   license wordnet

「any of the numbers (or symbols) that form a product when multiplied together」

WordNet   license wordnet

「an independent variable in statistics」

WordNet   license wordnet

「anything that contributes causally to a result; "a number of factors determined the outcome"」

PrepTutorEJDIC   license prepejdic

「(…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize」

WordNet   license wordnet

「consider as relevant when making a decision; "You must factor in the recent developments"」
factor in, factor out

WordNet   license wordnet

「resolve into factors; "a quantum computer can factor the number 15"」
factor in, factor out


fact」

  [★]

  • n.
actualactuallyin factin practiceindeedpractically

WordNet   license wordnet

「an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"」

WordNet   license wordnet

「a concept whose truth can be proved; "scientific hypotheses are not facts"」

WordNet   license wordnet

「a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"」

WordNet   license wordnet

「a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"」

PrepTutorEJDIC   license prepejdic

「〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行」

receptor」

  [★] 受容体

WordNet   license wordnet

「a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response」

PrepTutorEJDIC   license prepejdic

「=sense organ / 受信装置」




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