WordNet

of or relating to eosinophil
a leukocyte readily stained with eosin (同)eosinophile

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/30 02:09:01」(JST)

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Basophilic

Eosonophilic

Neutrophilic

A metamyelocyte is a cell undergoing granulopoiesis, derived from a myelocyte, and leading to a band cell.

It is characterized by the appearance of a bent nucleus, cytoplasmic granules, and the absence of visible nucleoli. (If the nucleus is not yet bent, then it is likely a myelocyte.)

Additional images

Hematopoiesis

External links

Histology image: 01805ooa – Histology Learning System at Boston University - "Bone Marrow and Hemopoiesis: bone marrow smear, neutrophilic metamyelocyte and mature PMN"
Histology image: 75_05 at the University of Oklahoma Health Sciences Center
Histology at KUMC blood-blood11
Histology at KUMC blood-blood12
Interactive diagram at lycos.es
Slide at marist.edu
hematologyatlas.com

This developmental biology article is a stub. You can help Wikipedia by expanding it.

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1. 末梢血塗抹標本の評価evaluation of the peripheral blood smear [show details]
… from myeloblast to promyelocyte to myelocyte to metamyelocyte to band form to mature neutrophil Only the last two of these stages,… Similar-looking inclusions, along with giant platelets, are seen in patients with the May-Hegglin anomaly. Eosinophils, normally present in small numbers (less than 5 percent of white cells), are recognized by their …
2. 好中球二次顆粒欠損症neutrophil specific granule deficiency [show details]
… whereas secondary or specific granule proteins are synthesized in myelocytes and metamyelocytes and tertiary or gelatinase granule proteins are generated… Eosinophils – Eosinophil granules are also affected in this disease. Eosinophils in patients with SGD cannot be…
3. 骨髄造血の制御regulation of myelopoiesis [show details]
… Metamyelocyte – Metamyelocytes are post-mitotic cells that are slightly smaller… monocytes, and lymphocytes, while the term granulocyte includes polymorphonuclear neutrophils (PMNs), eosinophils, and basophils. Myelopoiesis begins with the differentiation of a small pool of multipotent hematopoietic …
4. 小児や青年の好中球減少症の概要overview of neutropenia in children and adolescents [show details]
… noted on the differential analysis: Neutrophilic metamyelocytes and younger forms are not included in this calculation An ANC <1500/microL (<1.5… eosinophils, and basophils); however, almost all granulocytopenic patients are neutropenic since the number of neutrophils is so much larger than the number of eosinophils and basophils.…
5. 急性骨髄性白血病の分類classification of acute myeloid leukemia [show details]
… and metamyelocytes are often prominent and may be large; their cytoplasm has a waxy,…immature eosinophils that have large atypical purple-violet granules in addition to eosinophilic granules in the cytoplasm In typical cases, the bone marrow demonstrates abnormalities of the eosinophils in…

English Journal

Basophils and allergic inflammation.

Siracusa MC1, Kim BS, Spergel JM, Artis D.
The Journal of allergy and clinical immunology.J Allergy Clin Immunol.2013 Oct;132(4):789-801; quiz 788. doi: 10.1016/j.jaci.2013.07.046.
Basophils were discovered by Paul Ehrlich in 1879 and represent the least abundant granulocyte population in mammals. The relative rarity of basophils and their phenotypic similarities with mast cells resulted in this cell lineage being historically overlooked, both clinically and experimentally. Ho
PMID 24075190

Cyclopamine induces eosinophilic differentiation and upregulates CD44 expression in myeloid leukemia cells.

Takahashi T1, Kawakami K, Mishima S, Akimoto M, Takenaga K, Suzumiya J, Honma Y.
Leukemia research.Leuk Res.2011 May;35(5):638-45. doi: 10.1016/j.leukres.2010.09.022. Epub 2010 Oct 23.
Cyclopamine, a plant-derived steroidal alkaloid, inhibits the hedgehog (Hh) signaling pathway by antagonizing Smoothened. This drug can induce the differentiation of myeloid leukemia cell lines and acute myeloid leukemia (AML) cells in primary culture. The treated cells were stained with Luxol-fast-
PMID 20971508