WordNet
- want to have; "Id like a beer now!"
- a kind of person; "Well not see his like again"; "I cant tolerate people of his ilk" (同)ilk
- a similar kind; "dogs, foxes, and the like", "we dont want the likes of you around here" (同)the like, the likes of
- equal in amount or value; "like amounts"; "equivalent amounts"; "the same amount"; "gave one six blows and the other a like number"; "the same number" (同)same
- resembling or similar; having the same or some of the same characteristics; often used in combination; "suits of like design"; "a limited circle of like minds"; "members of the cat family have like dispositions"; "as like as two peas in a pod"; "doglike devotion"; "a dreamlike quality" (同)similar
- be fond of; "I like my nephews"
- feel about or towards; consider, evaluate, or regard; "How did you like the Presidents speech last night?"
- find enjoyable or agreeable; "I like jogging"; "She likes to read Russian novels"
- a feeling of pleasure and enjoyment; "Ive always had a liking for reading"; "she developed a liking for gin"
- found pleasant or attractive; often used as a combining form; "a well-liked teacher"
- Chinese distance measure; approximately 0.5 kilometers
PrepTutorEJDIC
- …‘を'『好む』,‘が'好きである / 《しばしば否定文で,またwould,《英》shouldと共に用いて》…‘を'望む,…したい / 『好む』;望む / 《複数形で》好み,好きな事
- (外観・性質などが)…『に似た』,のような / (やり方,程度などが)…『と同じように』 / …『らしい』,にふさわいし / 《おもに話》たとえば…のような / 《名詞の前にのみ用いて》(性質・外観などが)同じの,(数量が)等しい / 《補語にのみ用いて》似ている,そっくりで / たぶん,おそらく(probably) / (…に)似た人(物),(…と)同等の人(物),匹敵する人(物)《+『of』+『名』》 / …のように / あたかも…のように
- (…の)『好み』,趣味《+『for』(『to』)+『名』》
UpToDate Contents
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- 1. 大型の胃粘膜ひだ：過形成および非過形成性の胃疾患 large gastric folds hyperplastic and nonhyperplastic gastropathies
- 2. 多発性内分泌腫瘍1型：臨床症状および診断 multiple endocrine neoplasia type 1 clinical manifestations and diagnosis
- 3. ゾリンジャー - エリソン症候群（ガストリノーマ）の臨床症状および診断 clinical manifestations and diagnosis of zollinger ellison syndrome gastrinoma
- 4. 胃ポリープ gastric polyps
- 5. 化生（慢性）萎縮性胃炎 metaplastic chronic atrophic gastritis
English Journal
- Distinct Cellular Origins for Serotonin-Expressing and Enterochromaffin-like Cells in the Gastric Corpus.
- Li HJ1, Johnston B1, Aiello D2, Caffrey DR2, Giel-Moloney M3, Rindi G4, Leiter AB5.Author information 1Division of Gastroenterology, University of Massachusetts Medical School, Worcester, Massachusetts.2Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts.3Department of Medicine, Tufts Medical Center, Boston, Massachusetts.4Sacred Heart Hospital, Rome, Italy.5Division of Gastroenterology, University of Massachusetts Medical School, Worcester, Massachusetts; Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts. Electronic address: andrew.leiter@umassmed.edu.AbstractBACKGROUND & AIMS: The alimentary tract contains a diffuse endocrine system comprising enteroendocrine cells that secrete peptides or biogenic amines to regulate digestion, insulin secretion, food intake, and energy homeostasis. Lineage analysis in the stomach revealed that a significant fraction of endocrine cells in the gastric corpus did not arise from Neurogenin3 (Neurog3)-expressing cells, unlike enteroendocrine cells elsewhere in the digestive tract. We aimed to isolate enriched serotonin-secreting and enterochromaffin-like (ECL) cells from the stomach and to clarify their cellular origin.
- Gastroenterology.Gastroenterology.2014 Mar;146(3):754-764.e3. doi: 10.1053/j.gastro.2013.11.048. Epub 2013 Dec 4.
- BACKGROUND & AIMS: The alimentary tract contains a diffuse endocrine system comprising enteroendocrine cells that secrete peptides or biogenic amines to regulate digestion, insulin secretion, food intake, and energy homeostasis. Lineage analysis in the stomach revealed that a significant fractio
- PMID 24316261
- Transient receptor potential ankyrin 1 (TRPA1) channel activation by the thienopyridine-type drugs ticlopidine, clopidogrel, and prasugrel.
- Schulze A1, Hartung P1, Schaefer M1, Hill K2.Author information 1Rudolf-Boehm-Institute of Pharmacology and Toxicology, Medical Faculty, University of Leipzig, Leipzig, Germany.2Rudolf-Boehm-Institute of Pharmacology and Toxicology, Medical Faculty, University of Leipzig, Leipzig, Germany. Electronic address: kerstin.hill@medizin.uni-leipzig.de.AbstractTransient receptor potential A1 (TRPA1) is widely expressed throughout the human and animal organism, including the dorsal root ganglia as well as the bladder, stomach and small intestine. Here, we examined the effect of three platelet aggregation inhibitors on TRPA1: ticlopidine, clopidogrel and prasugrel. Utilising fluorometric Ca2+ influx analysis and electrophysiological whole cell measurements in TRPA1-expressing HEK293 and in human enterochromaffin-like QGP-1 cells, we found that ticlopidine, clopidogrel and prasugrel are direct activators of TRPA1. Although this polymodal channel commonly contributes to the perception of pain, temperature and chemical irritants, recent studies provide evidence for its involvement in the release of serotonin (5-HT) from enterochromaffin cells. Therefore, we further investigated the ability of ticlopidine, clopidogrel and prasugrel to stimulate 5-HT release from QGP-1 cells. We could determine 5-HT in supernatants from cultured QGP-1 cells upon treatment with ticlopidine and clopidogrel but not with prasugrel. These findings indicate that a robust TRPA1 activation by ticlopidine and clopidogrel correlates with the stimulatory effect on the secretion of 5-HT. As recipients of ticlopidine and clopidogrel frequently complain about gastrointestinal adverse events such as nausea, vomiting and diarrhoea, an activation of TRPA1 may contribute to adverse effects of such drugs in the digestive system.
- Cell calcium.Cell Calcium.2014 Feb 25. pii: S0143-4160(14)00036-0. doi: 10.1016/j.ceca.2014.02.014. [Epub ahead of print]
- Transient receptor potential A1 (TRPA1) is widely expressed throughout the human and animal organism, including the dorsal root ganglia as well as the bladder, stomach and small intestine. Here, we examined the effect of three platelet aggregation inhibitors on TRPA1: ticlopidine, clopidogrel and pr
- PMID 24636274
- Gastrin: from pathophysiology to cancer prevention and treatment.
- Maddalo G1, Spolverato Y, Rugge M, Farinati F.Author information 1aDepartment of Surgery, Oncology and Gastroenterology, Padua University Hospital bDepartment of Medicine, Padua University, Padova, Italy.AbstractGastrin has been identified as the principal effector of gastric secretion, but several studies have demonstrated its role as a biomarker of cancer risk and as a growth factor for colorectal, stomach, liver, and pancreatic cancer. Hypergastrinemia characterizes autoimmune gastritis, with body and fundic gland atrophy and increased risk for both gastric adenocarcinoma and neuroendocrine tumors. Gastric type I carcinoids develop in the context of autoimmune gastritis because of the stimulus exerted by gastrin on enterochromaffin-like cells and remain gastrin-sensitive for long durations because the removal of hypergastrinemia leads to tumor regression. The treatment of gastric carcinoid is still open to debate, but when the disease frequently relapses, or is multicentric or infiltrating, surgery is advocated or, in the alternative, a costly and long-lasting treatment with long-acting somatostatin analogues is prescribed. A technology allowing the preparation of an immunogen eliciting an immune system response with generation of antibodies against G17 has been developed. This vaccine has been tested in patients with colorectal, pancreatic or advanced gastric cancer. The vaccine has also been used in the treatment of gastric type I carcinoids, and the administration of G17DT in patients harboring these lesions leads to carcinoid regression. Antigastrin vaccination in the treatment of gastrointestinal cancer obviously needs validation, but this immunotherapy may well represent a simple, inexpensive, and active 'adjuvant' treatment.
- European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP).Eur J Cancer Prev.2014 Jan 26. [Epub ahead of print]
- Gastrin has been identified as the principal effector of gastric secretion, but several studies have demonstrated its role as a biomarker of cancer risk and as a growth factor for colorectal, stomach, liver, and pancreatic cancer. Hypergastrinemia characterizes autoimmune gastritis, with body and fu
- PMID 24469263
Japanese Journal
- ヒスタミン
- 里見 正隆
- 日本食品科学工学会誌 : Nippon shokuhin kagaku kogaku kaishi = Journal of the Japanese Society for Food Science and Technology 57(8), 366, 2010-08-15
- … 子式C5H9N3，分子量111.14の活性アミンで，アミノ酸であるヒスチジンの脱炭酸反応で誘導される．無色，無臭で一般的な加熱調理では分解しない．人体では肥満細胞のほか，好塩基球やECL細胞（enterochromaffin-like cell）がヒスタミン産生細胞として知られている．血圧降下，血管透過性亢進，平滑筋収縮，血管拡張，腺分泌促進などの薬理作用があり，アレルギー反応や炎症の発現に介在物質として働く …
- NAID 10026526056
- Unusual Multiple Gastric Carcinoids with Hypergastrinemia : Report of a Case
- NAKATA KOHEI,AISHIMA SHINICHI,ISHIMIYA HITOSHI,YAO TAKASHI,MATSUURA TAKASHI,SEO MITSURU,NAGAI EISHI,OKIDO MASAYUKI,KATO MASATO,NAKAGAKI MITSURU,TSUNEYOSHI MASAZUMI,TANAKA MASAO
- Surgery today : the Japanese journal of surgery 40(3), 267-271, 2010-03-01
- NAID 10027394684
Related Links
- Enterochromaffin-like or ECL cells are a distinctive type of neuroendocrine cell in the gastric mucosa underlying the epithelium. They are most prevalent in the acid-secreting regions of the stomach. ECL cells synthesize and secrete histamine ...
- Enterochromaffin-like cells; ECL Cells. On-line free medical diagnosis assistant. Ranked list of possible diseases from either several symptoms or a full patient history. A similarity measure between symptoms and diseases is ...
Related Pictures
★リンクテーブル★
| リンク元 | 「ECL」「enterochromaffinlike」「腸クロム親和性細胞様」 |
| 拡張検索 | 「enterochromaffin-like cells」「enterochromaffin-like cell」 |
| 関連記事 | 「like」「enterochromaffin」 |
「ECL」
「enterochromaffinlike」
「腸クロム親和性細胞様」
「enterochromaffin-like cells」
「enterochromaffin-like cell」
「like」
- v.
- prep.
- 似ている、同様の
- 関
- alike、as well as、care for、correspond、correspondingly、equally、favor、identically、likewise、prefer、resemble、same、similar、similarly、such
「enterochromaffin」
- 腸クロム親和性の、エンテロクロマフィン