endodeoxyribonuclease

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/06/27 20:55:23」(JST)

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Endodeoxyribonuclease is an endonuclease ribonuclease.

Restriction enzymes are a type of endodeoxyribonuclease.

It is a restriction enzyme that chews up DNA at its ends. This is why DNA is not linear. For example, during Transduction in bacterial cells, bacteriophage DNA is inserted in a bacterial cell. The DNA from the bacteriophage immediately circularizes in order to avoid getting "chewed up" by endodeoxyribonuclease at their ends.

More examples: Deoxyribonuclease I, Deoxyribonuclease II, Deoxyribonuclease IV, UvrABC endonuclease

External links

Endodeoxyribonucleases at the US National Library of Medicine Medical Subject Headings (MeSH)

This hydrolase article is a stub. You can help Wikipedia by expanding it.

English Journal

Exposure of hepatocellular carcinoma cells to low-level As₂O₃‎ causes an extra toxicity pathway via L1 retrotransposition ‎induction.

Karimi A1, Madjd Z2, Habibi L3, Akrami SM4.
Toxicology letters.Toxicol Lett.2014 Aug 17;229(1):111-7. doi: 10.1016/j.toxlet.2014.05.025. Epub 2014 Jun 21.
Various mechanisms have been proposed for toxicity and carcinogenesis pattern of arsenic, a naturally occurring metalloid. The extent to which the long interspersed element-1 (LINE-1) retrotransposon, an ubiquitous retroelement with autonomous mobility, can be influenced upon exposure to low-level a
PMID 24960058

DNase 1 retains endodeoxyribonuclease activity following gold nanocluster synthesis.

West AL1, Griep MH, Cole DP, Karna SP.
Analytical chemistry.Anal Chem.2014 Aug 5;86(15):7377-82. doi: 10.1021/ac5005794. Epub 2014 Jul 16.
Here we present the synthesis of the enzyme DNase 1 stabilized gold nanoclusters (DNase 1:AuNCs) with core size consisting of either 8 or 25 atoms. The DNase 1:Au8NCs exhibit blue fluorescence whereas the DNase 1:Au25NCs are red emitting. In addition to the intense fluorescence emission, the synthes
PMID 24999001

Associations study of vitamin D receptor gene polymorphisms with diabetic microvascular complications: a meta-analysis.

Liu Z1, Liu L2, Chen X1, He W1, Yu X3.
Gene.Gene.2014 Aug 1;546(1):6-10. doi: 10.1016/j.gene.2014.05.052. Epub 2014 May 24.
BACKGROUND: Emerging evidence from preclinical and clinical studies has shown that vitamin D plays an important role in the pathogenesis of diabetic microvascular complications (DMI). Several potentially functional polymorphisms (ApaI, BsmI, FokI and TaqI) of vitamin D receptor (VDR) gene have been
PMID 24862218

Japanese Journal

ラット肝細胞核より抽出したエンドデオキシリボヌクレアーゼによるDNA鋳型の特異的失活

秋吉博登,瀬尾クニ子,岩田大輔,Mia Mohammad Abdus Satter
徳島大学総合科学部自然科学研究 12, 1-8, 1999-01-05
NAID 110000503452

Purification and Properties of a Neutral Endodeoxyribonuclease from Rat Pancreatic Juice

穴井元昭,江島奈津子,松本富士子
九州大学医療技術短期大学部紀要 18, 1-9, 1991-03
DNase I was purified from rat pancreatic juice by a procedure including DEAE-cellulose and phosphocellulose chromatographies, Sephadex G-75 gel filtration and concanavalin A-Sepharose affinity chromat …
NAID 110000055156

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