encainide

出典: meddic

エンカイニド

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「antiarrhythmic drug (trade name Enkaid) used to treat life-threatening arrhythmias but increases the risk of sudden death in heart attack patients」
Enkaid

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/06/14 15:51:50」(JST)

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英文文献

  • Efficacy and potency of class I antiarrhythmic drugs for suppression of Ca2+ waves in permeabilized myocytes lacking calsequestrin.
  • Galimberti ES, Knollmann BC.SourceDivision of Clinical Pharmacology and Oates Institute for Experimental Therapeutics, Vanderbilt University School of Medicine, Nashville, USA.
  • Journal of molecular and cellular cardiology.J Mol Cell Cardiol.2011 Nov;51(5):760-8. Epub 2011 Jul 12.
  • Ca(2+) waves can trigger ventricular arrhythmias such as catecholaminergic-polymorphic ventricular tachycardia (CPVT). Drugs that prevent Ca(2+) waves may have antiarrhythmic properties. Here, we use permeabilized ventricular myocytes from a CPVT mouse model lacking calsequestrin (casq2) to screen a
  • PMID 21798265
  • [When and how to treat ventricular ectopic beats].
  • D'Este D, Sorbo MD.SourceU.O.C. di Cardiologia, Ospedale di Dolo (VE). daniele.deste@ulss13mirano.ven.it
  • Giornale italiano di cardiologia (2006).G Ital Cardiol (Rome).2010 Oct;11(10 Suppl 1):21S-26S.
  • Ventricular ectopic beats are commonly observed in daily clinical practice, either in symptomatic or asymptomatic subjects. In many subjects these arrhythmias are casually detected during a screening visit. Their occurrence is usually associated with no clinical significance. However, in some cases
  • PMID 21416822

和文文献

  • Mortality following ventricular arrhythmia suppression by Encainide, Flecainide and Moricizine after myocardial infarction
  • Increased risk of death and cardiac arrest from encainide and flecainide in patients after non-Q-wave acute myocardial infarction in the Cardiac Arrhythmia Suppression Trial
  • Mortality in patients treaated with flecainide and encainide for supraventricular arrhythmias

関連リンク

encainide /en·cai·nide/ (en-ka´nīd) a sodium channel blocker that acts on the Purkinje fibers and myocardium; used as the hydrochloride salt in treatment of life-threatening arrhythmias. encainide [en-ka´nīd] a sodium channel blocking agent ...
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関連画像

Encainide.svg structure of encainide hydrochloride7ed431880e15895417ab00e559c2be31.jpgLet Me BuyEncainide37612-13-8 encainide


★リンクテーブル★
リンク元CAST」「エンカイニド

CAST」

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cardiac arrhythmia supression trial
抗不整脈薬
  • 抗不整脈薬の役割を明確にするため施行させた大規模臨床試験
心筋梗塞後の心室期外収縮をIc群のencainideflecainideで抑制したところかえって突然死が増加した
→抗不整脈薬の催不整脈作用に対する薬物治療のあり方に変化


エンカイニド」

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encainide
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