emorfazone

出典: meddic

エモルファゾン

英文文献

  • 4-Amino-3(2H)-pyridazinones bearing arylpiperazinylalkyl groups and related compounds: synthesis and antinociceptive activity.
  • Piaz VD, Vergelli C, Giovannoni MP, Scheideler MA, Petrone G, Zaratin P.SourceDipartimento di Scienze Farmaceutiche, Università di Firenze, via G. Capponi 9, 50121 Firenze, Italy. vittorio.dalpiaz@unifi.it
  • Farmaco (Società chimica italiana : 1989).Farmaco.2003 Nov;58(11):1063-71.
  • A series of 4-amino-3(2H)-pyridazinones substituted at position 2 with arylpiperazinylalkyl groups and analogues were synthesized and their antinociceptive effect was evaluated in the mouse abdominal constriction model. Preliminary SARs studies were performed. Several of the novel compounds dosed at
  • PMID 14572856
  • [Studies on pyridazinone derivatives. XVI. Analgesic-antiinflammatory activities of 3(2H)-pyridazinone derivatives].
  • Takaya M, Sato M.SourceHamari Chemical Co., Ltd., Osaka, Japan.
  • Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.Yakugaku Zasshi.1994 Feb;114(2):94-110.
  • In order to examine analgesic and antiinflammatory activities of the position isomers of 4-ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone (1, emorfazone), an analgesic-antiinflammatory drug, 5-ethoxy-2-methyl-4-morpholino-3(2H)-pyridazinone (2), 6-ethoxy-2-methyl-4-morpholino-3(2H)-pyridazinone (3)
  • PMID 8169774

和文文献

  • ピリダジノン誘導体の研究(第16報)3(2H)-ピリダジノン誘導体の合成と鎮痛消炎作用
  • 高谷 昌弘,佐藤 誠
  • 藥學雜誌 114(2), 94-110, 1994-02-25
  • … In order to examine analgesic and antiinflammatory activities of the position isomers of 4-ethoxy-2-methyl-5-morpholino-3 (2H)-pyridazinone (1,emorfazone), an analgesic-antiinflammatory drug, 5-ethoxy-2-methyl-4-morpholino-3 (2H)-pyridazinone (2), 6-ethoxy-2-methyl-4-morpholino-3 (2H)-pyridazinone (3) and 6-ethoxy-2-methyl-5-morpholino-3 (2H)-pyridazinone (4) were prepared. …
  • NAID 110003649471
  • <Abstract of annual report>Photochemical Oxidation of 4-Ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone (Emorfazone) by Pyrimido[5,4-g]pteridine 5-Oxide.
  • MAKI YOSHIFUMI,SHIMADA KAORU,SAKO MAGOICHI,KITADE YUKIO,HIROTA KOSAKU
  • 岐阜藥科大學紀要 38, 52, 1989-06-30
  • NAID 110000052751

関連リンク

Emorfazone is a medicine available in a number of countries worldwide. A list of US medications equivalent to Emorfazone is available on the Drugs.com website.
Effects of 4-ethoxy-3-methyl-5-morpholino-3(2H)-pyridazinone (emorfazone, M 73101) on thermic edema in rats were investigated, and following results were obtained: Oral administration of emorfazone (100 and 200 mg/kg) significantly ...

関連画像

合成方法〗Figure imgb0004wherein R is an aryl or heteroaryl ring Services on DemandEmorfazone (cas 38957-41-4) Molecular DEFLAMINE (CellsCare) - bromelain


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