efavirenz

出典: meddic

エファビレンツ

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/02/25 05:50:14」(JST)

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英文文献

  • Nevirapine-related adverse events among children switched from efavirenz to nevirapine as compared to children who were started on nevirapine-based antiretroviral therapy directly.
  • Sanjeeva GN1, Sukanya V, Pavithra HB, Dodderi SK, Rewari BB, Govindaraj M, Shivananda S, Premalatha R.
  • AIDS care.AIDS Care.2015 May;27(5):655-9. doi: 10.1080/09540121.2014.987103. Epub 2014 Dec 17.
  • In this retrospective study, incidence of nevirapine (NVP) toxicity in children who were switched from efavirenz (EFV) to NVP (treatment experienced [TE] group) was compared with that of children who had started NVP-based antiretroviral therapy directly (treatment naïve [TN] group). This study also
  • PMID 25517472
  • Faldaprevir and pegylated interferon α-2a/ribavirin in individuals co-infected with hepatitis C virus genotype-1 and HIV.
  • Dieterich D1, Nelson M, Soriano V, Arastéh K, Guardiola JM, Rockstroh JK, Bhagani S, Laguno M, Tural C, Ingiliz P, Jain MK, Stern JO, Manero M, Vinisko R, Kort J; STARTVerso4 study group.
  • AIDS (London, England).AIDS.2015 Mar 13;29(5):571-81. doi: 10.1097/QAD.0000000000000579.
  • OBJECTIVE: Faldaprevir is a potent, once-daily hepatitis C virus (HCV) NS3/4A protease inhibitor. STARTVerso4 assessed the efficacy and safety of faldaprevir and response-guided pegylated interferon α-2a/ribavirin (PegIFN/RBV) in individuals with HCV/HIV co-infection.DESIGN: A phase 3 open-label st
  • PMID 25710287
  • Efficacy of tenofovir and efavirenz in combination with lamivudine or emtricitabine in antiretroviral-naive patients in Europe.
  • Swartz JE1, Vandekerckhove L2, Ammerlaan H3, de Vries AC1, Begovac J4, Bierman WF5, Boucher CA6, van der Ende ME7, Grossman Z8, Kaiser R9, Levy I8, Mudrikova T10, Paredes R11, Perez-Bercoff D12, Pronk M3, Richter C13, Schmit JC14, Vercauteren J15, Zazzi M16, Židovec Lepej S4, De Luca A17, Wensing AM; on behalf of the European Society for translational Antiviral Research (ESAR).
  • The Journal of antimicrobial chemotherapy.J Antimicrob Chemother.2015 Mar 3. pii: dkv033. [Epub ahead of print]
  • BACKGROUND: The combination of tenofovir and efavirenz with either lamivudine or emtricitabine (TELE) has proved to be highly effective in clinical trials for first-line treatment of HIV-1 infection. However, limited data are available on its efficacy in routine clinical practice.METHODS: A multicen
  • PMID 25740950

和文文献

  • The Effect of the Different Treatment Protocols on Virological and Immunological Responses in Patients with HIV/AIDS
  • Sari Nagehan Didem,Fincanci Muzaffer,Soysal Ferda
  • Japanese Journal of Infectious Diseases 67(5), 339-344, 2014
  • … As the largest clusters, the lopinavir/ritonavir-based patient group (Group 1, n = 29) and efavirenz-based patient group (Group 2, n = 18) were compared. …
  • NAID 130004692231
  • A simple, rapid, economical, and practical method for the determination of efavirenz in plasma of Chinese AIDS patients by reverse phase high-performance liquid chromatography with ultraviolet detector
  • Yin Kang,Meng Xianmin,Dong Ping,Ding Tianran,Shen Li,Zhang Li,Zhang Renfang,Cai Weimin,Lu Hongzhou
  • BioScience Trends 8(4), 227-234, 2014
  • … This study aimed to develop a reverse phase high-performance liquid chromatographic (RP-HPLC) method for the determination of efavirenz in human plasma and to use it for determining the concentrations of efavirenz in Chinese AIDS patient. … Diazepam was used as an internal standard and monitored with efavirenz at 247 nm. …
  • NAID 130004690256
  • Pharmacogenetics and Clinical Biomarkers for Subtherapeutic Plasma Efavirenz Concentration in HIV-1 Infected Thai Adults
  • SUKASEM Chonlaphat,CHAMNANPHON Montri,KOOMDEE Napatrupron,SANTON Siwalee,JANTARAROUNGTONG Thawinee,PROMMAS Santirat,PUANGPETCH Apichaya,MANOSUTHI Weerawat
  • Drug Metabolism and Pharmacokinetics 29(4), 289-295, 2014
  • … The aim of this study was to assess the influence of host genetic variations and clinical factors in relation to efavirenz level in HIV-1 infected Thai adults. … A total of 100 HIV-infected subjects treated with efavirenz/lamivudine/tenofivir were prospectively enrolled. … At steady state, plasma efavirenz concentrations were measured using high performance liquid chromatography. …
  • NAID 130004463386

関連リンク

Efavirenz (EFV, brand names Sustiva and Stocrin) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.
Drug information on Efavirenz for patients and consumers.

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efavirenz
ストックリン、Sustiva, EFV






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