WordNet

an hour early in the morning
very young; "at an early age"
before the usual time or the time expected; "she graduated early"; "the house was completed ahead of time" (同)ahead of time, too soon
in good time; "he awoke betimes that morning" (同)betimes
belonging to the distant past; "the early inhabitants of Europe"; "former generations"; "in other times" (同)former, other
at or near the beginning of a period of time or course of events or before the usual or expected time; "early morning"; "an early warning"; "early diagnosis"; "an early death"; "took early retirement"; "an early spring"; "early varieties of peas and tomatoes mature before most standard varieties"
being or occurring at an early stage of development; "in an early stage"; "early forms of life"; "early man"; "an early computer"
expected in the near future; "look for an early end to the negotiations"
of an early stage in the development of a language or literature; "the Early Hebrew alphabetical script is that used mainly from the 11th to the 6th centuries B.C."; "Early Modern English is represented in documents printed from 1476 to 1700"
a period of time equal to 1/24th of a day; "the job will take more than an hour" (同)hr, 60 minutes
clock time; "the hour is getting late" (同)time of day
a special and memorable period; "it was their finest hour"
distance measured by the time taken to cover it; "we live an hour from the airport"; "its just 10 minutes away" (同)minute
fruiting spike of a cereal plant especially corn (同)spike, capitulum
attention to what is said; "he tried to get her ear"
good hearing; "he had a keen ear"; "a good ear for pitch"
the sense organ for hearing and equilibrium
the time period between dawn and noon; "I spent the morning running errands" (同)morn, morning time, forenoon

PrepTutorEJDIC

(時間・時期が)『早い』,『初期の』 / 昔の / (普通より,予定より)早い / 近い将来の / (時間・時期的に)『早く』 / (予定・ふだんより)早く
〈C〉(60分としての)『1時間』(《略》h,H,hr,複hrs) / 〈C〉(時計で示される)『時刻』,時 / 〈C〉(ある事をする)特定の時間,定刻 / 〈C〉(一般的な)時,時間 / 《複数形》勤務(営業)時間 / 〈C〉1時間の道のり / 〈C〉(授業の)1時間,1時限;(大学などの)履習単位(1週間の授業時間数) / 《the~》現在
〈C〉『耳』 / 《単数形で》『聴覚』,聴力,音感 / 《単数形で》じっと聞くこと,傾聴 / 〈C〉耳の形をした物
(麦・とうもろこしなどの)穂
〈C〉〈U〉『朝』,午前(午前0時または夜明けから正午まで) / 〈U〉《the~》(物事の)始まり,夜明け,黎明(れいめい)《+『of』+『名』》 / 《名詞の前にのみ用いて》朝の
ほう(驚き・賞賛・冷笑などの発声);お‐い(呼びかけ・注意などの発声)
娼婦・売春婦：（whoreの発音をくずしたもの）

UpToDate Contents

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1. 成人における早期発症の認知症 early onset dementia in adults
2. 原発性（本態性）高血圧における薬物療法の選択：推奨 choice of drug therapy in primary essential hypertension recommendations
3. ステロイド服用中の外科患者 the surgical patient taking glucocorticoids
4. 副腎不全におけるACTHに対する反応の評価 evaluation of the response to acth in adrenal insufficiency
5. 成人における未分化の早期炎症性関節炎 undifferentiated early inflammatory arthritis in adults

English Journal

Seizure occurrence and the circadian rhythm of cortisol: a systematic review.

van Campen JS1, Valentijn FA2, Jansen FE2, Joëls M3, Braun KP2.
Epilepsy & behavior : E&B.Epilepsy Behav.2015 May 13. pii: S1525-5050(15)00250-4. doi: 10.1016/j.yebeh.2015.04.071. [Epub ahead of print]
PURPOSE: Stress is the seizure precipitant most often reported by patients with epilepsy or their caregivers. The relation between stress and seizures is presumably mediated by stress hormones such as cortisol, affecting neuronal excitability. Endogenous cortisol is released in a circadian pattern.
PMID 25982883

Sleep Duration and Disturbances Were Associated With Testosterone Level, Muscle Mass, and Muscle Strength-A Cross-Sectional Study in 1274 Older Men.

Auyeung TW1, Kwok T2, Leung J3, Lee JS2, Ohlsson C4, Vandenput L4, Wing YK5, Woo J2.
Journal of the American Medical Directors Association.J Am Med Dir Assoc.2015 May 8. pii: S1525-8610(15)00294-7. doi: 10.1016/j.jamda.2015.04.006. [Epub ahead of print]
BACKGROUND: Testosterone level follows a circadian rhythm. However, whether sleep duration and disturbances can affect testosterone level, muscle mass, and strength remains unknown.OBJECTIVE: To examine the relationship of sleep duration and disturbances to testosterone level, muscle mass, muscle st
PMID 25959075

Chronomodulated drug delivery system of urapidil for the treatment of hypertension.

Chaudhary SS1, Patel HK1, Parejiya PB1, Shelat PK1.
International journal of pharmaceutical investigation.Int J Pharm Investig.2015 Apr-Jun;5(2):107-13. doi: 10.4103/2230-973X.153389.
INTRODUCTION: Hypertension is a disease which shows circadian rhythm in the pattern of two peaks, one in the evening at about 7pm and other in the early morning between 4 am to 8 am. Conventional therapies are incapable to target those time points when actually the symptoms get worsened. To achieve
PMID 25838996