Frontiers in bioscience (Landmark edition).Front Biosci (Landmark Ed).2017 Jan 1;22:1-20.
Recent research on translation and protein synthesis in several pathologies, including cancer, peripheral artery disease, and wound healing, demonstrates the key role played by translational factors in tumorigenic and angiogenic processes. This review will focus on one specific translational factor,
eIF3 Regulation of Protein Synthesis, Tumorigenesis, and Therapeutic Response.
Yin JY1, Dong Z2, Zhang JT3.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2017;1507:113-127.
Translation initiation is the rate-limiting step of protein synthesis and highly regulated. Eukaryotic initiation factor 3 (eIF3) is the largest and most complex initiation factor consisting of 13 putative subunits. A growing number of studies suggest that eIF3 and its subunits may represent a new g
The eukaryotic translation initiation factor, eIF4G, plays a key functional role in the initiation of cap-dependent translation by acting as an adapter to nucleate the assembly of eIF4F complex. Together with poly(A)-binding protein and eIF3, eIF4F subsequently triggers the recruitment of 43S riboso
Conserved synteny of genes between chromosome 15 of Bombyx mori and a chromosome of Manduca sexta shown by five-color BAC-FISH
Sahara Ken,Yoshido Atsuo,Marec František,Fuková Iva,Zhang Hong-Bin,Wu Cheng-Cang,Goldsmith Marian R.,Yasukochi Yuji
Genome 50(11), 1061-1065, 2007-11-01
… mori LG15 genes (RpP0, RpS8, eIF3, RpL7A, RpS23, and Hsc70) for the tobacco hornworm, Manduca sexta, and selected the ortholog-containing BAC clones from an M. …