ジストロフィン結合タンパク質複合体
WordNet
- having partial rights and privileges or subordinate status; "an associate member"; "an associate professor"
- a person who joins with others in some activity or endeavor; "he had to consult his associate before continuing"
- a person with subordinate membership in a society, institution, or commercial enterprise; "associates in the law firm bill at a lower rate than do partners"
- any event that usually accompanies or is closely connected with another; "first was the lightning and then its thunderous associate"
- make a logical or causal connection; "I cannot connect these two pieces of evidence in my mind"; "colligate these facts"; "I cannot relate these events at all" (同)tie_in, relate, link, colligate, link up, connect
- complicated in structure; consisting of interconnected parts; "a complex set of variations based on a simple folk melody"; "a complex mass of diverse laws and customs"
- a compound described in terms of the central atom to which other atoms are bound or coordinated (同)coordination_compound
- a conceptual whole made up of complicated and related parts; "the complex of shopping malls, houses, and roads created a new town" (同)composite
- (psychoanalysis) a combination of emotions and impulses that have been rejected from awareness but still influence a persons behavior
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
PrepTutorEJDIC
- 〈人〉'を'(…の)『仲間に加える』,(…に)連合させる《+『名』〈人〉+『with』+『名』》 / (…と)…'を'結びつけて考える(起こす)《+『名』+『with』+『名』》 / (…と)『仲間になる』,交際する《+『with』+『名』》 / (…と)合体する,提携する《+『with』+『名』》 / 『仲間』,『同僚』;組合員 / 準会員 / 付属物;連想されるもの / 連合した;仲間の,同僚の / 補助の,準…
- 『いくつかの部分から成る』,複合の,合成の / 『複雑な』,入りくんだ,こみいった(complicated) / 複合体,合成物 / コンプレックス,複合(抑圧されて心に残った複雑なしこり)
- 蛋白(たんばく)質
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/08/10 02:57:56」(JST)
[Wiki en表示]
The dystrophin-associated protein complex is a multiprotein complex that includes dystrophin and the dystrophin-associated proteins.[1]
Many forms of muscular dystrophy are associated with disorders of the dystrophin-associated protein complex.[2]
References
- ^ Dystrophin-Associated Protein Complex at the US National Library of Medicine Medical Subject Headings (MeSH)
- ^ Ehmsen J, Poon E, Davies K (July 2002). "The dystrophin-associated protein complex". J. Cell. Sci. 115 (Pt 14): 2801–3. PMID 12082140.
See also
Histology: Muscle tissue (TH H2.00.05, H3.3)
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Smooth
muscle |
- Calmodulin
- Vascular smooth muscle
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Striated
muscle |
Skeletal
muscle |
Costamere/
DAPC |
Membrane/
extracellular |
DAP: |
- Sarcoglycan
- SGCA
- SGCB
- SGCD
- SGCE
- SGCG
- SGCZ
- Dystroglycan
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- Sarcospan
- Laminin, alpha 2
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Intracellular |
- Dystrophin
- Dystrobrevin
- Syntrophin
- Syncoilin
- Dysbindin
- Synemin/desmuslin
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related: |
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Sarcomere/
(a, i, and h bands;
z and m lines) |
- Myofilament
- thin filament/actin
- thick filament/myosin
- elastic filament/titin
- nebulin
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Connective tissue |
- Epimysium
- Fascicle
- Perimysium
- Endomysium
- Connective tissue in skeletal muscle
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General |
- Neuromuscular junction
- Motor unit
- Muscle spindle
- Excitation–contraction coupling
- Sliding filament mechanism
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Cardiac
muscle |
- Myocardium
- Intercalated disc
- Nebulette
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Both |
Fiber |
- Muscle fiber
- Myofibril
- Microfilament/Myofilament
- Sarcomere
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Cells |
- Myoblast/Myocyte
- Myosatellite cell
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Other |
- Desmin
- Sarcoplasm
- Sarcolemma
- Sarcoplasmic reticulum
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Other/
ungrouped |
- Myotilin
- Telethonin
- Dysferlin
- Fukutin
- Fukutin-related protein
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anat (h/n, u, t/d, a/p, l)/phys/devp/hist
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noco (m, s, c)/cong (d)/tumr, sysi/epon, injr
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UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Perturbations in skeletal muscle sarcomere structure of heart failure and type 2 diabetes patients: Restorative effects of (-)-epicatechin-rich cocoa.
- Taub PR, Ramirez-Sanchez I, Ciaraldi TP, Gonzalez-Basurto S, Coral-Vazquez R, Perkins G, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F.AbstractHeart failure and type 2 diabetes mellitus associate with detrimental alterations in skeletal muscle structure/function. We have demonstrated that (-)-epicatechin rich cocoa (ERC) improves skeletal muscle mitochondrial structure (Taub et al, 2012. Clin Trans Sci. 5, 43). We hypothesized that improved mitochondrial structure may facilitate the reversal of detrimental alterations in sarcomeric microstructure. In a pilot study, five patients with heart failure and type 2 diabetes consumed ERC for three months; treadmill testing (VO2 max) and skeletal muscle biopsies were performed. Westerns, immunohistochemistry and electron microscopy were used. We report severe perturbations in components of the dystrophin-associated protein complex (DAPC) as well as sarcomeric microstructure at baseline. ERC induced recovery/enhancement of DAPC protein levels, sarcomeric microstructure and in a coordinated fashion alterations in markers of skeletal muscle growth/differentiation consistent with myofiber regeneration. VO2 max increased (~24%) but did not reach statistical significance. These initial results warrant further rigorous investigation, since the use of ERC (or pure epicatechin) may represent a safe and novel means of improving muscle function.
- Clinical science (London, England : 1979).Clin Sci (Lond).2013 May 3. [Epub ahead of print]
- Heart failure and type 2 diabetes mellitus associate with detrimental alterations in skeletal muscle structure/function. We have demonstrated that (-)-epicatechin rich cocoa (ERC) improves skeletal muscle mitochondrial structure (Taub et al, 2012. Clin Trans Sci. 5, 43). We hypothesized that improve
- PMID 23642227
- Effects of prednisolone on the dystrophin-associated proteins in the blood-brain barrier and skeletal muscle of dystrophic mdx mice.
- Tamma R, Annese T, Capogrosso RF, Cozzoli A, Benagiano V, Sblendorio V, Ruggieri S, Crivellato E, Specchia G, Ribatti D, De Luca A, Nico B.SourceDepartment of Basic Medical Sciences, Neurosciences and Sensory Organs, Section of Human Anatomy and Histology, University of Bari Medical School, Bari, Italy.
- Laboratory investigation; a journal of technical methods and pathology.Lab Invest.2013 May;93(5):592-610. doi: 10.1038/labinvest.2013.46. Epub 2013 Mar 25.
- The mdx mouse, the most widely used animal model of Duchenne muscular dystrophy (DMD), develops a seriously impaired blood-brain barrier (BBB). As glucocorticoids are used clinically to delay the progression of DMD, we evaluated the effects of chronic treatment with α-methyl-prednisolone (PDN) on t
- PMID 23528847
- Rescue of dystrophic skeletal muscle by PGC-1α involves restored expression of dystrophin associated protein complex components and satellite cell signaling.
- Hollinger K, Gardan-Salmon D, Santana C, Rice D, Snella E, Selsby JT.Source1Iowa State University.
- American journal of physiology. Regulatory, integrative and comparative physiology.Am J Physiol Regul Integr Comp Physiol.2013 Apr 17. [Epub ahead of print]
- Duchenne muscular dystrophy is typically diagnosed in the preschool years because of locomotor defects, indicative of muscle damage. Thus, effective therapies must be able to rescue muscle from further decline. We have established that Peroxisome proliferator-activated receptor gamma co-activator 1-
- PMID 23594613
Japanese Journal
- The dystrophin associated protein complex in zebrafish
- Dystrophin-associated protein complex and heart failure
Related Links
- 15 Jul 2002 ... In skeletal and cardiac muscle, dystrophin associates with various proteins to form the dystrophin-associated protein complex (DAPC). The DAPC is thought to play a structural role in linking the actin cytoskeleton to the ...
- The dystrophin-associated protein complex is a multiprotein complex that includes dystrophin and the dystrophin-associated proteins. Many forms of muscular dystrophy are associated with disorders of the dystrophin-associated protein ...
Related Pictures
★リンクテーブル★
[★]
- 英
- dystrophin-associated protein complex
[★]
- 結合する、連合させる。連想によって結びつける。(人を)仲間/友達などとしての関係に置く。(化)会合させる
- 仲間/友人などとして交際する(with)。一つにまとめる、連合する
- 仕事仲間、提携者、同僚。友人、朋友。準会員。従業員、社員
- 密接な蒸す偽付きのある物、付随する物、つきもの。準国家
- 連想によって心に浮かぶ言葉/思い、連想物
- 仲間の、同僚の。製紙機械員に次ぐ資格の
- 付随する、連想される
- 関
- accompany、association、associative、attach、bearing、bind、binding、bond、bonding、coassemble、colleague、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、correlate、correlation、couple、dock、engage、engagement、federation、implication、join、joint、ligate、link、linkage、peer、pertinent、reference、relate、relation、relationship、relative、relevance、relevant、symphysial、union
[★]
- 関
- complexes、complicated、composite、conjugate、intricate
[★]
- 関
- hybrid、mixed lineage、mixed type、mixed-type
[★]
- 関
- concomitant、erratic、erratically
- associate
[★]