duck hepatitis B virus

• アヒルB型肝炎ウイルス

関

DHBV

WordNet

1. to move (the head or body) quickly downwards or away; "Before he could duck, another stone struck him"
2. (cricket) a score of nothing by a batsman (同)duck''s egg
3. a heavy cotton fabric of plain weave; used for clothing and tents
4. small wild or domesticated web-footed broad-billed swimming bird usually having a depressed body and short legs
5. flesh of a duck (domestic or wild)
6. submerge or plunge suddenly
7. a harmful or corrupting agency; "bigotry is a virus that must not be allowed to spread"; "the virus of jealousy is latent in everyone"
8. (virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein
9. a software program capable of reproducing itself and usually capable of causing great harm to files or other programs on the same computer; "a true virus cannot spread to another computer without human assistance" (同)computer virus
10. the 2nd letter of the Roman alphabet (同)b
11. the blood group whose red cells carry the B antigen (同)type_B, group B
12. inflammation of the liver caused by a virus or a toxin
13. hunting ducks (同)duck hunting

PrepTutorEJDIC

1. 〈C〉『アヒル』,『カモ』 / 〈C〉雌のカモ,雌のアヒル / 〈U〉(食用にする)カモ,アヒルの肉 / 〈C〉《おもに英話》かわいい人
2. (特に打たれたり見つかったりするのを避けるために)〈頭〉‘を'ひょいと下げる,〈体〉‘を'急にかがめる / 《話》〈打撃・いやなことなど〉‘を'ひょいとかわす / 〈人〉‘を'ちょっと水に沈める / 頭をひょいと下げる,身をかがめる / 《副詞[句]を伴って》ひょいと身をかわす / 頭や体をひょいと下げる(かがめる)こと;身をかわすこと / ちょっと水に潜ること
3. 〈U〉ズック / 《複数形で》ズック製のズボン
4. ビールス,ろ過性病原体
5. 肝[臓]炎

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/08/18 10:39:04」(JST)

wiki en

[Wiki en表示]

Duck hepatitis B virus
Virus classification
Group:	Group VII (dsDNA-RT)
Order:	Unassigned
Family:	Hepadnaviridae
Genus:	Avihepadnavirus
Species:	Duck hepatitis B virus

Duck Hepatitis B virus, abbreviated DHBV, is part of the Avihepadnavirus genus of the Hepadnaviridae, and is the causal agent of duck hepatitis B.

DHBV is a small DNA virus with a diameter of 40–45 nm. The viral envelope is made up from host cell lipid, with viral surface antigens (DHBsAg). The icosahedral nucleocapsid within, is composed of the virus core antigen (DHBcAg) and surrounds the DNA genome and viral polymerase. The viral genome is a circular double stranded DNA molecule about 3000 base pairs long. The genome has three overlapping open reading frames or ORFs:

• C-ORF – encoding the core antigen and pre-core protein which are processed and secreted as DHBcAg
• S-ORF – codes for the surface antigen DHBsAg
• P-ORF – encoding the viral polymerase.

On binding and entry of the virus to the host cell, the genome is transported to the nucleus to be transcribed. Novel viral RNA is then transferred to the cytoplasm for translation and subsequent protein synthesis.

The Duck Hepatitis B virus has provided a basis for the use of vaccines and prophylactic treatments for individuals at high risk of human Hepatitis B virus (HBV). The virus has also provided as a useful animal model in the absence of one from the HBV.

UpToDate Contents

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• 1. 小児におけるB型肝炎ウイルス感染の概要 overview of hepatitis b virus infection in children
• 2. B型肝炎の管理の概要および症例 overview of the management of hepatitis b and case examples
• 3. 慢性B型肝炎ウイルス感染に対する従来型インターフェロンおよびペグインターフェロン standard and pegylated interferon for chronic hepatitis b virus infection
• 4. 慢性B型肝炎ウイルス感染に対する肝移植 liver transplantation for chronic hepatitis b virus infection
• 5. 慢性B型肝炎ウイルス感染の治療におけるエンテカビル entecavir in the treatment of chronic hepatitis b virus infection

English Journal

• Regulation of multiple stages of hepadnavirus replication by the carboxyl-terminal domain of viral core protein in trans.

• Liu K1, Ludgate L2, Yuan Z3, Hu J4.
• Journal of virology.J Virol.2015 Mar;89(5):2918-30. doi: 10.1128/JVI.03116-14. Epub 2014 Dec 24.
• Mutational analyses have indicated that the carboxyl-terminal domain (CTD) of hepadnavirus core protein and its state of phosphorylation are critical for multiple steps in viral replication. Also, CTD interacts with host proteins in a phosphorylation state-dependent manner. To ascertain the role of
• PMID 25540387

• Effect of alcohol extract of Acanthus ilicifolius L. on anti-duck hepatitis B virus and protection of liver.

• Wei PH1, Wu SZ1, Mu XM1, Xu B1, Su QJ1, Wei JL1, Yang Y1, Qin B1, Xie ZC2.
• Journal of ethnopharmacology.J Ethnopharmacol.2015 Feb 3;160:1-5. doi: 10.1016/j.jep.2014.10.050. Epub 2014 Nov 25.
• ETHNOPHARMACOLOGICAL RELEVANCE: Acanthus ilicifolius L. is an important medicinal mangrove plant. It is popularly used for its anti-inflammatory, antioxidant activity and hepatoprotective effects. The present study was conducted to evaluate the effect of treatment with alcohol extract of Acanthus il
• PMID 25446633

• The pregenome/C RNA of duck hepatitis B virus is not used for translation of core protein during the early phase of infection in vitro.

• Liu Q1, Huang J1, Jia R2, Wang M3, Zhu D4, Chen S3, Liu M3, Yin Z5, Wang Y5, Cheng A6.
• Virus research.Virus Res.2015 Jan 22;196:13-9. doi: 10.1016/j.virusres.2014.10.026. Epub 2014 Nov 7.
• Over the course of duck hepatitis B virus (DHBV) replication, one type of RNA (pregenome/C RNA, 3.5 kb) that corresponds to the whole genome of DHBV is generated from the transcription of viral cccDNA. Previous work has proposed three functions for the pregenome/C RNA: it can serve as the pregenome
• PMID 25449362

Japanese Journal

• Microbiological identification and analysis of waterfowl livers collected from backyard farms in southern China

• LIU Rongchang,FU Qiuling,LIN Jiansheng,CHEN Cuiteng,HUANG Yu,CHENG Longfei,LU Ronghui,FU Guanghua,SHI Shaohua,CHEN Hongmei,WAN Chunhe
• Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ 80(4), 667-671, 2018
• … The virus that was most commonly isolated was avian influenza virus, with a 12.1% positivity rate. …
• NAID 130006727609

• An outbreak of duck hepatitis A virus type 1 infection in Japan

• KAMOMAE Masahiro,KAMEYAMA Mamoru,ISHII Jun,NABE Mikoto,OGURA Yuji,ISEKI Hiroshi,YAMAMOTO Yu,MASE Masaji
• Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ 79(5), 917-920, 2017
• … By performing a reverse transcription-polymerase chain reaction (RT-PCR) using primers specific for duck hepatitis A virus type 1 (DHAV-1), we obtained the PCR products of a predicted size. … To our knowledge, this is the first time that the DHAV-1 virus has been isolated since its outbreak in Japan in 1963.</p> …
• NAID 130005665600

• Anti-hepatitis B Virus Activity of <i>α</i>-DDB-FNCG, a Novel Nucleoside-Biphenyldicarboxylate Compound In Vitro and In Vivo

• Yang Qinghua,Zhao Xuejie,Yu Wenquan [他],Yu Wenquan,He Wu,Fang Xianzhen,Zang Limin,Wan Na,Wang Qingduan,Zheng Liyun
• Journal of Pharmacological Sciences 126(3), 208-215, 2014
• A novel codrug, <i>α</i>-DDB-FNCG, was synthesized through coupling of <i>α</i>-biphenyl dimethyl dicarboxylate (<i>α</i>-DDB) and the nucleoside analogue FNCG, via …
• NAID 130004704279

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★リンクテーブル★

リンク元	「DHBV」「アヒルB型肝炎ウイルス」
関連記事	「B」「duck」「virus」

「DHBV」

　　[★]

• アヒルB型肝炎ウイルス

関

duck hepatitis B virus

「アヒルB型肝炎ウイルス」

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英

duck hepatitis B virus、DHBV

「B」

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• 気管分岐部下緑
• 補体のalternative pathwayに関わる蛋白質

• Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する

　 　

「duck」

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アヒル 　 　 　 　 　 　 　 　 　

「virus」

　　[★] ウイルス