WordNet

imprudently incurring risk; "do something rash that he will forever repent"- George Meredith
any red eruption of the skin (同)roseola, efflorescence, skin_rash
a series of unexpected and unpleasant occurrences; "a rash of bank robberies"; "a blizzard of lawsuits" (同)blizzard
use recreational drugs (同)do drugs
administer a drug to; "They drugged the kidnapped tourist" (同)dose
a substance that is used as a medicine or narcotic

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Raltegravir Plus Nevirapine as Maintenance Antiretroviral Therapy in HIV-Positive Patients: Safety, Efficacy and Pharmacokinetics.

Calcagno A1, Montrucchio C, Capetti A, Guaraldi G, Cenderello G, Calza L, Lanzafame M, Marinaro L, Tettoni MC, Trentini L, D'Avolio A, Di Perri G, Bonora S.
Current HIV research.Curr HIV Res.2016;14(1):54-60.
BACKGROUND: Tolerability, long-term toxicities and selection of resistant variants limit the use and efficacy of antiretroviral drugs in HIV-positive patients. Novel combinations are needed for mantaining long-term control of HIV replication; nevertheless scarse data are available on protease inhibi
PMID 26415700

Allopurinol induces innate immune responses through mitogen-activated protein kinase signaling pathways in HL-60 cells.

Nakajima A1, Oda S1, Yokoi T1.
Journal of applied toxicology : JAT.J Appl Toxicol.2015 Dec 7. doi: 10.1002/jat.3272. [Epub ahead of print]
Allopurinol, an inhibitor of xanthine oxidase, is a frequent cause of severe cutaneous adverse reactions (SCARs) in humans, including drug rash with eosinophilia and systemic symptoms, Stevens-Johnson syndrome and toxic epidermal necrolysis. Although SCARs have been suspected to be immune-mediated,
PMID 26641773

Power AE1, Graudins LV1, McLean CA1, Hopper I2.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.Am J Health Syst Pharm.2015 Dec 1;72(23):2061-3. doi: 10.2146/ajhp150171.
PURPOSE: The case of a patient who experienced a severe adverse reaction requiring emergency treatment after a single dose of fenofibrate is described.SUMMARY: A 58-year-old woman with type 1 diabetes was hospitalized for treatment of an extensive blistering rash on the buttocks and trunk accompanie
PMID 26581932

池谷由貴,畑康樹,山本奈緒,小栗豊子
Medical Mycology Journal 55(1), J19-J23, 2014
　58歳，女性．血小板減少性紫斑病，狭心症にて投薬加療中．初診の１週間前より左アキレス腱に虫刺症様皮疹あり．3，4日前より同部が浅い膿瘍となり，その後左下肢全体に発赤・腫脹を認め，圧痛を伴ってきたため他院を受診し，セフジニル（CFDN）カプセルを１日分処方され，当院を紹介受診した．初診時，発熱などの全身症状を認めず，左踵に膿瘍，左下肢にリンパ管に沿った線状の発赤・熱感を認め，左鼠径部リンパ節腫脹も …
NAID 130003397218

Successful Telaprevir Treatment in Combination of Cyclosporine against Recurrence of Hepatitis C in the Japanese Liver Transplant Patients

Kikuchi Mio,Okuda Yuki,Ueda Yoshihide [他],Nishioka Yuki,Uesugi Miwa,Hashimoto Emina,Takahashi Tamotsu,Kawai Tomoki,Hashi Sachiyo,Shinke Haruka,Omura Tomohiro,Yonezawa Atsushi,Ito Takashi,Fujimoto Yasuhiro,Kaido Toshimi,Chiba Tsutomu,Uemoto Shinji,Matsubara Kazuo,Masuda Satohiro
Biological and Pharmaceutical Bulletin 37(3), 417-423, 2014
… In 3 patients, the dose of TVR was decreased two-thirds of starting dose because of adverse effects, including anorexia and skin rash. …
NAID 130003382131

Quantitative Evaluation of Initial Symptoms as Predictors to Detect Adverse Drug Reactions Using Bayes' Theory: Expansion and Evaluation of Drug-Adverse Drug Reaction?Initial Symptom Combinations Using Adverse Event Reporting System Database

小林大介,保坂茂,井上絵美子,大島公恵,久津間信明,大島新司,奥野恭史
Biological and Pharmaceutical Bulletin 36(12), 1891-1901, 2013-12
… In prescription dispensing in Japan, to avoid adverse drug reactions (ADR) pharmacists provide patients with information concerning the initial symptoms (IS) of any ADR that might be caused by the drugs they have been prescribed. … We previously performed a trial calculation of the usefulness of rash as a predictor of drug-induced liver disorders by applying Bayes' theorem and showed that the predictive utility of IS can be quantitatively evaluated using likelihood ratios. …
NAID 120005397276