doxazosin

出典: meddic

ドキサゾシン

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「an antihypertensive drug (trade name Cardura) that works by relaxing blood vessels so that blood passes through them more easily; it is also used to treat benign prostatic hyperplasia」
Cardura

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/01/01 01:11:42」(JST)

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英文文献

  • Highly sensitive spectrofluorimetric method for determination of doxazosin through derivatization with fluorescamine; Application to content uniformity testing.
  • Omar MA1, Hammad MA2, Salman BI3, Derayea SM1.
  • Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.Spectrochim Acta A Mol Biomol Spectrosc.2016 Mar 15;157:55-60. doi: 10.1016/j.saa.2015.12.012. Epub 2015 Dec 17.
  • A highly sensitive, simple and selective spectrofluorimetric method has been developed and validated for determination of doxazosin mesylate in pure form, pharmaceutical formulations and human plasma. The method is based on the reaction between doxazosin mesylate and fluorescamine in Teorell buffer
  • PMID 26716887
  • Synthesis, vasorelaxant activity and 2D-QSAR study of some novel pyridazine derivatives.
  • George RF1, Saleh DO2.
  • European journal of medicinal chemistry.Eur J Med Chem.2016 Jan 27;108:663-73. doi: 10.1016/j.ejmech.2015.12.015. Epub 2015 Dec 12.
  • Novel 3,6-disubstituted pyridazines were synthesized by facile method and screened for their vasorelaxant properties utilizing isolated thoracic rat aortic rings. Compounds 8a and 11a exerted potent vasorelaxant activity (IC50 = 198 and 177 μM, respectively) relative to doxazosin mesylate (used
  • PMID 26735908
  • Reappraisal of Antihypertensive Medicine Doxazosin and Carvedilol as a Potential Therapeutic for Hepatic Fibrosis.
  • Paik YH1,2.
  • Gut and liver.Gut Liver.2016 Jan 23;10(1):10-1. doi: 10.5009/gnl15576.
  • PMID 26696027

和文文献

  • Determination of doxazosin and verapamil in human serum by fast LC-MS/MS : Application to document non-compliance of patients
  • CHYTIL Lukas,STRAUCH Branislav,CVACKA Josef,MARESOVA Vera,WIDIMSKY Jiri Jr.,HOLAJ Robert,SLANAR Ondrej
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 878(30), 3167-3173, 2010-11-15
  • NAID 10028044040
  • Enantioselective determination of doxazosin in human plasma by liquid chromatography-tandem mass spectrometry using ovomucoid chiral stationary phase
  • LIU Ke,ZHONG Dafang,CHEN Xiaoyan
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 878(26), 2415-2420, 2010-09-15
  • NAID 10028041004
  • α-Blockers in the treatment of male voiding dysfunction: how do they work and why do they differ in tolerability? (Forum minireview: The forefront for novel therapeutic agents based on the pathophysiology of lower urinary tract dysfunction)
  • Michel Martin C.
  • Journal of pharmacological sciences 112(2), 151-157, 2010-02
  • NAID 40016992203

関連リンク

Doxazosin official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. ... In one fixed-dose study (STUDY 2), Doxazosin mesylate therapy (4 to 8 mg, once ...
Doxazosin is in a group of drugs called alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. Doxazosin relaxes your veins and arteries so that blood can more easily pass through them. It also relaxes the muscles in the prostate and ...

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