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1. T細胞受容体シグナル伝達 t cell receptor signaling
2. 髄芽腫の組織病理および分子学的病因 histopathology and molecular pathogenesis of medulloblastoma
3. 頭頸部の扁平上皮癌化：分子学的および遺伝学的変化 head and neck squamous cell carcinogenesis molecular and genetic alterations
4. リードスタンバーグ細胞およびホジキンリンパ腫の病因 the reed sternberg cell and the pathogenesis of hodgkin lymphoma
5. 肝線維症の病因 pathogenesis of hepatic fibrosis

Failure to Target RANKL Signaling Through p38-MAPK Results in Defective Osteoclastogenesis in the Microphthalmia Cloudy-Eyed Mutant.

Carey HA1, Bronisz A2, Cabrera J1, Hildreth BE 3rd1,3, Cuitiño M1, Fu Q1, Ahmad A1, Toribio RE3, Ostrowski MC1, Sharma SM1.
Journal of cellular physiology.J Cell Physiol.2016 Mar;231(3):630-40. doi: 10.1002/jcp.25108.
The Microphthalmia-associated transcription factor (MITF) is a basic helix-loop-helix leucine zipper family factor that is essential for terminal osteoclast differentiation. Previous work demonstrates that phosphorylation of MITF by p38 MAPK downstream of Receptor Activator of NFkB Ligand (RANKL) si
PMID 26218069

Henderson-Redmond AN1, Guindon J2, Morgan DJ3.
Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2016 Feb 4;65:330-9. doi: 10.1016/j.pnpbp.2015.06.011. Epub 2015 Jun 26.
Alcohol use disorder represents a significant human health problem that leads to substantial loss of human life and financial cost to society. Currently available treatment options do not adequately address this human health problem, and thus, additional therapies are desperately needed. The endocan
PMID 26123153

Insulin signaling genes modulate nicotine-induced behavioral responses in Caenorhabditis elegans.

Wescott SA1, Ronan EA, Xu XZ.
Behavioural pharmacology.Behav Pharmacol.2016 Feb;27(1):44-9. doi: 10.1097/FBP.0000000000000186.
Insulin signaling has been suggested to modulate nicotine dependence, but the underlying genetic evidence has been lacking. Here, we used the nematode, Caenorhabditis elegans, to investigate whether genetic alterations in the insulin signaling pathway affect behavioral responses to nicotine. For thi
PMID 26317299