背外側前頭前皮質
WordNet
- the tissue forming the outer layer of an organ or structure in plant or animal
- anterior to a frontal structure; "a prefrontal bone"; "prefrontal lobes"
PrepTutorEJDIC
- (内臓,特に脳の)皮質 / (植物の)皮層;樹皮
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/02/11 22:52:47」(JST)
[Wiki en表示]
| Brain: Dorsolateral prefrontal cortex |
| Latin |
Cortex praefrontalis dorsolateralis |
The dorsolateral prefrontal cortex (DL-PFC or DLPFC) is an area in the primate brain. It is, according to a more restricted definition, roughly equivalent to Brodmann areas 9 and 46.[1] According to a broader definition, DL-PFC consists of the lateral portions of Brodmann areas 9 – 12, of areas 45, 46, and the superior part of area 47.[2] These regions mainly receive their blood supply from the middle cerebral artery. With respect to neurotransmitter systems, there is evidence that dopamine plays a particularly important role in DL-PFC.[2]
DL-PFC is connected to the orbitofrontal cortex, and to a variety of brain areas, which include the thalamus, parts of the basal ganglia (specifically, the dorsal caudate nucleus), the hippocampus, and primary and secondary association areas of neocortex, including posterior temporal, parietal, and occipital areas.[2]
DL-PFC is the last area, 45th, to myelinate in the human cerebrum.[citation needed]
|
Contents
- 1 Function
- 1.1 Truth Telling
- 1.2 Lucid dream states
- 2 References
- 3 See also
|
Function
DL-PFC serves as the highest cortical area responsible for motor planning, organization, and regulation. It plays an important role in the integration of sensory and mnemonic information and the regulation of intellectual function and action. It is also involved in working memory. However, DL-PFC is not exclusively responsible for the executive functions. All complex mental activity requires the additional cortical and subcortical circuits with which the DL-PFC is connected.[2][3]
Damage to the DL-PFC can result in the dysexecutive syndrome,[4] which leads to problems with affect, social judgement, executive memory, abstract thinking and intentionality.[5]
Truth Telling
The DL-PFC may also be involved in the act of deception and lying, which is thought to inhibit normal propensity to truth telling. Research suggests that using TMS on the DL-PFC can hamper a person's ability to lie, or indeed to tell the truth. [6]
Lucid dream states
More recent research has found a connection between the DL-PFC and lucid dream states in which executive function is retained. [7]
References
- ^ http://www.mrc-cbu.cam.ac.uk/people/jessica.grahn/neuroanatomy.html
- ^ a b c d Philip David Zelazo and Ulrich Muller: Executive function in typical and atypical development, in: Usha Goswam (ed): Blackwell Handbook of Child Cognitive Development, 2002
- ^ Hale & Fiorello: School neuropsychology, 2004
- ^ http://www.indianjpsychiatry.org/article.asp?issn=0019-5545;year=2009;volume=51;issue=3;spage=180;epage=190;aulast=John
- ^ http://www.neuro.spc.org/vaughan/ExecutiveFunctionLecture.pdf
- ^ http://www.newscientist.com/article/mg21128284.400-powerful-magnets-hamper-our-ability-to-lie.html
- ^ http://www.newscientist.com/article/mg20827815.700-50-ideas-to-change-science-neuroscience.html
See also
- Mesocortical pathway
- Cognitive control
- Working memory
- Attention versus memory in prefrontal cortex
- Attentional shift
- Wisconsin Card Sorting Test
|
Human brain: forebrain (cerebrum, cerebral cortex, cerebral hemispheres, grey matter) (TA A14.1.09.002–240, 301–320, GA 9.818–826)
|
|
| Frontal lobe |
| Superolateral |
| Prefrontal |
- Superior frontal gyrus
- Middle frontal gyrus
- Inferior frontal gyrus: 11l
- 47-Pars orbitalis
- Broca's area
- 44-Pars opercularis
- 45-Pars triangularis
- Superior frontal sulcus
- Inferior frontal sulcus
|
|
| Precentral |
- Precentral gyrus
- Precentral sulcus
|
|
|
| Medial/inferior |
| Prefrontal |
- Superior frontal gyrus
- Medial frontal gyrus
- Paraterminal gyrus/Paraolfactory area
- Straight gyrus
- Orbital gyri/Orbitofrontal cortex
- Ventromedial prefrontal cortex
- Subcallosal area
- Olfactory sulcus
- Orbital sulci
|
|
| Precentral |
- Paracentral lobule
- Paracentral sulcus
|
|
|
| Both |
- Primary motor cortex
- Premotor cortex
- Supplementary motor area
- Frontal eye fields
|
|
|
| Parietal lobe |
| Superolateral |
- Superior parietal lobule
- Inferior parietal lobule
- 40-Supramarginal gyrus
- 39-Angular gyrus
- Parietal operculum
|
|
| Medial/inferior |
- Paracentral lobule
- Precuneus
Marginal sulcus
|
|
| Both |
- Postcentral gyrus/primary somatosensory cortex
- Secondary somatosensory cortex
- Posterior parietal cortex
|
|
|
| Occipital lobe |
| Superolateral |
- Occipital pole of cerebrum
- Lateral occipital gyrus
- Lunate sulcus
- Transverse occipital sulcus
|
|
| Medial/inferior |
- Primary visual cortex
- Cuneus
- Lingual gyrus
|
|
|
| Temporal lobe |
| Superolateral |
- Transverse temporal gyrus/Primary auditory cortex
- Superior temporal gyrus
- Middle temporal gyrus
- Inferior temporal gyrus
- Superior temporal sulcus
- Inferior temporal sulcus
|
|
| Medial/inferior |
- Fusiform gyrus
- Medial temporal lobe
|
|
|
Interlobar
sulci/fissures |
| Superolateral |
- Central (frontal+parietal)
- Lateral (frontal+parietal+temporal)
- Parieto-occipital
- Preoccipital notch
|
|
| Medial/inferior |
- Medial longitudinal
- Cingulate (frontal+cingulate)
- Collateral (temporal+occipital)
- Callosal sulcus
|
|
|
| Limbic lobe |
| Parahippocampal gyrus |
- anterior
- Entorhinal cortex
- Perirhinal cortex
- Posterior parahippocampal gyrus
- Prepyriform area
|
|
| Cingulate cortex/gyrus |
- Subgenual area
- Anterior cingulate
- Posterior cingulate
- Isthmus of cingulate gyrus: Retrosplenial cortex
|
|
| Hippocampal formation |
- Hippocampal sulcus
- Fimbria of hippocampus
- Dentate gyrus
- Rhinal sulcus
|
|
| Other |
- Supracallosal gyrus
- Uncus
|
|
|
| Insular lobe |
- Long gyrus of insula
- Short gyri of insula
- Circular sulcus of insula
|
|
| General |
- Operculum
- Poles of cerebral hemispheres
|
|
|
Some categorizations are approximations, and some Brodmann areas span gyri.
|
|
anat (n/s/m/p/4/e/b/d/c/a/f/l/g)/phys/devp
|
noco (m/d/e/h/v/s)/cong/tumr, sysi/epon, injr
|
proc, drug (N1A/2AB/C/3/4/7A/B/C/D)
|
|
|
|
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- The effect of caffeine on working memory load-related brain activation in middle-aged males.
- Klaassen EB, de Groot RH, Evers EA, Snel J, Veerman EC, Ligtenberg AJ, Jolles J, Veltman DJ.SourceSchool for Mental Health and Neuroscience (MHeNS), Department of Psychiatry and Neuropsychology, Maastricht University, The Netherlands; AZIRE Research Institute & Faculty of Psychology and Education, VU University Amsterdam, The Netherlands. Electronic address: e.b.klaassen@vu.nl.
- Neuropharmacology.Neuropharmacology.2013 Jan;64(1):160-7. doi: 10.1016/j.neuropharm.2012.06.026. Epub 2012 Jun 21.
- Caffeine is commonly consumed in an effort to enhance cognitive performance. However, little is known about the usefulness of caffeine with regard to memory enhancement, with previous studies showing inconsistent effects on memory performance. We aimed to determine the effect of caffeine on working
- PMID 22728314
- Equivalent brain SPECT perfusion changes underlying therapeutic efficiency in pharmacoresistant depression using either high-frequency left or low-frequency right prefrontal rTMS.
- Richieri R, Boyer L, Padovani R, Adida M, Colavolpe C, Mundler O, Lançon C, Guedj E.SourceHôpital Sainte Marguerite, Pôle de Psychiatrie Universitaire, 13009 Marseille, France; Université d'Aix-Marseille, EA 3279, Unité de Recherche Santé Perçue, 13005 Marseille, France. Electronic address: raphaellemarie.richieri@ap-hm.fr.
- Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2012 Dec 3;39(2):364-70. doi: 10.1016/j.pnpbp.2012.07.012. Epub 2012 Jul 29.
- BACKGROUND: Functional neuroimaging studies have suggested similar mechanisms underlying antidepressant effects of distinct therapeutics.OBJECTIVE: This study aimed to determine and compare functional brain patterns underlying the antidepressant response of 2 distinct protocols of repetitive transcr
- PMID 22850205
Japanese Journal
- 過敏性腸症候群におけるうつ・不安・身体化のcomorbidity(精神科疾患とのcomorbidityが問題となる身体科疾患,2013年,第54回日本心身医学会総会ならびに学術講演会(横浜))
- 福土 審
- 心身医学 54(11), 1034-1038, 2014-11-01
- 過敏性腸症候群(irritable bowel syndrome: IBS)では,通常の一般臨床検査で把握される形態変化を欠くにもかかわらず,腹痛と便通異常に代表される下部消化管症状が慢性,再発性に持続する.IBSは頻度が高く,患者の生活の質を障害し,早期社会不適応の重大な原因となり,不安障害,うつ病性障害,身体表現性障害とのcomorbidityが高い.IBSの病態は,消化管生理学,微生物学,ゲ …
- NAID 110009865706
- Brain activity during the flow experience : A functional near-infrared spectroscopy study
- Yoshida Kazuki,Sawamura Daisuke,Inagaki Yuji,Ogawa Keita,Ikoma Katsunori,Sakai Shinya
- Neuroscience Letters 573, 30-34, 2014-06
- … Although flow is likely associated with many functions of the prefrontal cortex (PFC), such as attention, emotion, and reward processing, no study has directly investigated the activity of the PFC during flow. … During the flow condition, oxy-Hb concentration was significantly increased in the right and left ventrolateral prefrontal cortex. …
- NAID 120005464720
- Neural activities in cortical areas induced by listening to vocalized sentences measured by fMRI : Comparison between inductive and deductive reasoning
- Nakayama Yuki,Nozawa Kyohei,Hisano Shohei [他]
- 聴覚研究会資料 = Proceedings of the auditory research meeting 44(4), 203-207, 2014-05-30
- NAID 40020128493
Related Links
- (画像引用元:｢認知障害とは？（2） 前頭葉機能障害と認知障害｣) 背外側前頭前野(前頭前野背外側部 Dorsolateral prefrontal cortex)は、 脳の中で最も進化した部位であり、自発的な活動をする能力、他に気を散らさずに一つの仕事に集中 ...
- The first ever rap video explaining the workings of the dorsolateral prefrontal cortex, the psychiatrist's brain. Featuring renowned psychiatrist and educator Dr. Stephen M. Stahl, this short educational ...
★リンクテーブル★
[★]
背外側前頭前皮質 dorsolateral prefrontal cortex
[★]
- 英
- dorsolateral prefrontal cortex, DLPFC
[★]
- 関
- prefrontal area、prefrontal cortex
[★]
前頭前野
- 関
- prefrontal、prefrontal area
[★]
[★]