dopamine receptor antagonist

出典: meddic


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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/05/17 22:20:39」(JST)

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  • Role of the D3 dopamine receptor in nicotine sensitization.
  • Smith LN1, Bachus SE2, McDonald CG2, Smith RF2.
  • Behavioural brain research.Behav Brain Res.2015 Aug 1;289:92-104. doi: 10.1016/j.bbr.2015.04.025. Epub 2015 Apr 20.
  • Adolescent cigarette use is associated with reduced quitting success and continued smoking in adulthood. Interestingly, polymorphisms of the dopamine D3 receptor (DRD3) gene have been associated with smoking behavior, and the receptor is expressed in an age- and brain region-dependent manner that su
  • PMID 25907750
  • Neuroprotection in Parkinsonian-treated mice via estrogen receptor α activation requires G protein-coupled estrogen receptor 1.
  • Bourque M1, Morissette M2, Di Paolo T3.
  • Neuropharmacology.Neuropharmacology.2015 Aug;95:343-52. doi: 10.1016/j.neuropharm.2015.04.006. Epub 2015 Apr 17.
  • We have previously shown that estrogen receptors (ER) α activation and G protein-coupled estrogen receptor 1 (GPER1) stimulation reproduce 17β-estradiol protection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced toxicity of dopamine neurons in mice. This suggests that both ERα and GP
  • PMID 25892506
  • Serotonin6 receptors in the dorsal hippocampus regulate depressive-like behaviors in unilateral 6-hydroxydopamine-lesioned Parkinson's rats.
  • Liu KC1, Li JY1, Tan HH2, Du CX2, Xie W3, Zhang YM3, Ma WL1, Zhang L4.
  • Neuropharmacology.Neuropharmacology.2015 Aug;95:290-8. doi: 10.1016/j.neuropharm.2015.03.031. Epub 2015 Apr 9.
  • Preclinical studies indicate both activation and blockade of serotonin6 (5-HT6) receptors may produce antidepressant-like effects. Depression is a common symptom in Parkinson's disease (PD); however, its pathophysiology is unclear. Here we examined whether 5-HT6 receptors in the dorsal hippocampus (
  • PMID 25863121


  • がん疼痛治療と医療用麻薬
  • Antidepressant-Like Effects of Sanggenon G, Isolated from the Root Bark of Morus alba, in Rats: Involvement of the Serotonergic System
  • 先端巨大症の治療戦略


Dopamine receptor antagonist Dopaminergic blockers Drug class Skeletal structor formula of Haloperidol, a typical antipsychotic Use Schizophrenia, bipolar disorder, nausea and vomiting, etc. Biological target Dopamine receptors ...
Dopamine receptor antagonists As peripheral and central dopaminergic receptors are rather similar, the specificity of action of an antagonist on peripheral or central receptors depends primarily on its pharmacokinetic features. If ...






dopamine antagonistdopaminergic antagonist, dopamine receptor antagonist
ドパミン受容体拮抗薬ドパミン受容体遮断薬ドパミン拮抗薬ドパミン遮断薬抗ドパミン薬 antidopaminergic agent
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  [★] 拮抗薬

WordNet   license wordnet

「a drug that neutralizes or counteracts the effects of another drug」

WordNet   license wordnet

「a muscle that relaxes while another contracts; "when bending the elbow the triceps are the antagonist"」

PrepTutorEJDIC   license prepejdic



  [★] 受容体

WordNet   license wordnet

「a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response」

PrepTutorEJDIC   license prepejdic

「=sense organ / 受信装置」


  [★] ドパミン DA

WordNet   license wordnet

「a monoamine neurotransmitter found in the brain and essential for the normal functioning of the central nervous system; as a drug (trade names Dopastat and Intropin) it is used to treat shock and hypotension」
Dopastat, Intropin