disease of the neuromuscular junction

　

WordNet

1. a disease characterized by impairment of neuromuscular junctions
2. a special situation; "this thing has got to end"; "it is a remarkable thing"
3. a separate and self-contained entity
4. an action; "how could you do such a thing?"
5. an artifact; "how does this thing work?"
6. an entity that is not named specifically; "I couldnt tell what the thing was"
7. any attribute or quality considered as having its own existence; "the thing I like about her is ..."
8. a persistent illogical feeling of desire or aversion; "he has a thing about seafood"; "she has a thing about him"
9. a special abstraction; "a thing of the spirit"; "things of the heart"
10. a special objective; "the thing is to stay in bounds"
11. a statement regarded as an object; "to say the same thing in other terms"; "how can you say such a thing?"
12. an event; "a funny thing happened on the way to the..."
13. an impairment of health or a condition of abnormal functioning
14. the state of being joined together (同)conjunction, conjugation, colligation
15. an act of joining or adjoining things (同)adjunction
16. something that joins or connects (同)conjunction
17. the place where two or more things come together

PrepTutorEJDIC

1. 〈C〉(形のある)『物』,物体;(生物に対しての)『無生物』 / 〈C〉(形のない)『もの』,事,事柄,でき事 / 《複数形で》事情,事態,状勢,状況 / 《複数形で》(すべての)事物,事柄 / 《通例 the~》(努力・活動などの)目的,目標 / 〈C〉衣服,衣類・《one's things》持ち物,所持品,身の回り品 / 《複数形で》道具,用具・〈C〉《親愛・哀れみ・軽べつなどの感情をこめて》人,者,やつ / 《the~》《話》(…の)流行《+in+名》
2. 《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
3. (体の)『病気』,疾患 / (精神・道徳などの)病気,病弊
4. 女性の話術芸人 =diseur
5. 《前述の名詞または文脈でそれと分かる名詞に付けて》『その』,あの,名の / 《唯一の事物に付けて》 / 《方角・自然現象に付けて》 / 《用具・楽器・特定の病気などに付けて》 / 《修飾吾[句]を伴う名詞に付けて》 / 《単数普通名詞に付けて》(1)《種族全体》…『というもの』 / 《複数名詞または集合名詞に付けて》 / 《単位》『…につき;…単位[で]』 / 《身体の一部に付けて,所有格に代わる》 / 《形容詞に付けて》 / 《固有名詞に付けて》 / 《強意用法に》『随一の』,典型的な / 《「the+比較級,the+比較級」の形で》『…すればするほどそれだけ』 / 《比較級の前に》(…につれて,のために)『それだけ』,ますます
6. 〈U〉〈C〉連結すること(された状態),『結合』,連合,合体 / 〈C〉『結合点』,連結(接合,合流)点 / 〈C〉(鉄道の)『連絡駅』,接続駅

UpToDate Contents

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• 1. 神経筋接合部に作用する毒素の概要 overview of neuromuscular junction toxins
• 2. 新生児および幼児における神経筋接合部障害 neuromuscular junction disorders in newborns and infants
• 3. 新生児における筋緊張低下を引き起こす末梢神経および筋肉の障害に関する概要 overview of peripheral nerve and muscle disorders causing hypotonia in the newborn
• 4. 末梢神経疾患および筋疾患の鑑別診断 differential diagnosis of peripheral nerve and muscle disease
• 5. 眼瞼下垂症の概要 overview of ptosis

English Journal

• α-Synuclein A30P decreases neurodegeneration and increases synaptic vesicle release probability in CSPα-null mice.

• Ruiz R, Biea IA, Tabares L.SourceDepartment of Medical Physiology and Biophysics, School of Medicine, University of Seville, Avda. Sanchez Pizjuan 4, 41009 Seville, Spain. Electronic address: rruiz@upo.es.
• Neuropharmacology.Neuropharmacology.2014 Jan;76 Pt A:106-17. doi: 10.1016/j.neuropharm.2013.08.032. Epub 2013 Sep 11.
• α-Synuclein and Cysteine-string protein-α (CSPα) are presynaptic proteins that participate in the maintenance of synaptic function. Mutations or overexpression of the wild type form of α-synuclein have been related to Parkinson's disease, and CSPα mutations cause one type of neuronal ceroid lip
• PMID 24036317

• Three-dimensional neuron-muscle constructs with neuromuscular junctions.

• Morimoto Y, Kato-Negishi M, Onoe H, Takeuchi S.SourceCenter for International Research on Micronano Mechatronics (CIRMM), Institute of Industrial Science (IIS), The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.
• Biomaterials.Biomaterials.2013 Dec;34(37):9413-9. doi: 10.1016/j.biomaterials.2013.08.062. Epub 2013 Sep 14.
• This paper describes a fabrication method of muscle tissue constructs driven by neurotransmitters released from activated motor neurons. The constructs consist of three-dimensional (3D) free-standing skeletal muscle fibers co-cultured with motor neurons. We differentiated mouse neural stem cells (mN
• PMID 24041425

• Vaccination in patients with disorders of the muscle and neuromuscular junction.

• Esposito S, Passera S.SourceDepartment of Pathophysiology and Transplantation, Pediatric Clinic 1, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milano, Italy.
• Expert review of vaccines.Expert Rev Vaccines.2013 Nov;12(11):1341-9. doi: 10.1586/14760584.2013.841341. Epub 2013 Oct 16.
• Neuromuscular diseases cover a broad spectrum of conditions that have important differences. Infections are frequently associated with severe complications, mainly because the neurological involvement can cause the aspiration of respiratory secretions and be significantly worsened by progressive res
• PMID 24127832

Japanese Journal

• Lambert–Eaton myasthenic syndrome: Clinical review

• Clinical and Experimental Neuroimmunology 7(3), 238-245, 2016-08
• NAID 120006221225

• 重症筋無力症

• 神経治療学 33(3), 318-322, 2016
• NAID 130005279096

• 不動・廃用症候群

• The
• NAID 130005068617

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★リンクテーブル★

関連記事	「disease」「junction」「thing」

「disease」

　　[★]

• n.

疾患：illnessより厳密な概念。「ある臓器に明確な障害が確認され、それによって症状が出ているとはっきり説明できる場合」 (PSY.9)

特定の原因、病態生理、症状、経過、予後、病理組織所見が全てそろった場合 (PSY.9)

• something that is very wrong with people's attitudes, way of life or with society.

関

ail、ailment、disease entity、disorder、ill、illness、malady、sick、sickness

• 注意

disease ≠ illness ≠ disorder

　 　 　

「junction」

　　[★]

• n.

• 接合部、移行部、接合点、ジャンクション

関

junctional、junctional region、juncture

　 　 　 　 　

「thing」

　　[★]