ジペプチジルペプチダーゼ
- 関
- dipeptidyl aminopeptidase、dipeptidylpeptidase、DPP
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/10/05 14:59:45」(JST)
[Wiki en表示]
Dipeptidyl peptidase is a type of enzyme classified under EC 3.4.14.
Types include:
- Cathepsin C, dipeptidyl peptidase-1[1]
- Dipeptidyl-peptidase II
- DPP3, dipeptidyl peptidase-3
- Dipeptidyl peptidase-4
- DPP6, dipeptidyl peptidase-6
- DPP7, dipeptidyl peptidase-7
- DPP8, dipeptidyl peptidase-8
- DPP9, dipeptidyl peptidase-9
- DPP10, dipeptidyl peptidase-10
See also
References
- ^ Dipeptidyl Peptidases at the US National Library of Medicine Medical Subject Headings (MeSH)
|
Hydrolase: proteases (EC 3.4)
|
|
| 3.4.11-19: Exopeptidase |
| 3.4.11 |
- Aminopeptidase
- Alanine
- Arginyl
- Aspartyl
- Cystinyl
- Leucyl
- Glutamyl
- Methionyl
- O
|
|
| 3.4.13 |
|
|
| 3.4.14 |
- Dipeptidyl peptidase
- Cathepsin C
- Dipeptidyl peptidase-4
- Tripeptidyl peptidase
- Tripeptidyl peptidase I
- Tripeptidyl peptidase II
|
|
| 3.4.15 |
- Angiotensin-converting enzyme
|
|
| 3.4.16 |
- Serine type carboxypeptidases: Cathepsin A
- DD-transpeptidase
|
|
| 3.4.17 |
- Metalloexopeptidases
- Carboxypeptidase
- A
- A2
- B
- C
- E
- Glutamate II
|
|
| Other/ungrouped |
|
|
|
| 3.4.21-25: Endopeptidase |
- Serine protease
- Cysteine protease
- Aspartic acid protease
- Metalloendopeptidase
- Threonine endopeptidase
- Proteasome endopeptidase complex
- HslU—HslV peptidase
- Other/ungrouped: Amyloid precursor protein secretase
- Alpha secretase
- Beta-secretase 1
- Beta-secretase 2
- Gamma secretase
|
|
| 3.4.99: Unknown |
|
|
Enzymes
|
|
| Activity |
- Active site
- Binding site
- Catalytic triad
- Oxyanion hole
- Enzyme promiscuity
- Catalytically perfect enzyme
- Coenzyme
- Cofactor
- Enzyme catalysis
- Enzyme kinetics
- Lineweaver–Burk plot
- Michaelis–Menten kinetics
|
|
| Regulation |
- Allosteric regulation
- Cooperativity
- Enzyme inhibitor
|
|
| Classification |
- EC number
- Enzyme superfamily
- Enzyme family
- List of enzymes
|
|
| Types |
- EC1 Oxidoreductases(list)
- EC2 Transferases(list)
- EC3 Hydrolases(list)
- EC4 Lyases(list)
- EC5 Isomerases(list)
- EC6 Ligases(list)
|
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- A study to evaluate the potential of an in silico approach for predicting dipeptidyl peptidase-IV inhibitory activity in vitro of protein hydrolysates.
- Wang TY1, Hsieh CH2, Hung CC3, Jao CL4, Lin PY5, Hsieh YL2, Hsu KC6.
- Food chemistry.Food Chem.2017 Nov 1;234:431-438. doi: 10.1016/j.foodchem.2017.05.035. Epub 2017 May 8.
- PMID 28551257
- Renoprotective effects of a dipeptidyl peptidase 4 inhibitor in a mouse model of progressive renal fibrosis.
- Uchida T1, Oda T2, Matsubara H1, Watanabe A1, Takechi H1, Oshima N1, Sakurai Y3, Kumagai H1.
- Renal failure.Ren Fail.2017 Nov;39(1):340-349. doi: 10.1080/0886022X.2017.1279553.
- PMID 28118775
- Effect of concomitant administration of coenzyme Q10 with sitagliptin on experimentally induced diabetic nephropathy in rats.
- Maheshwari R1, Balaraman R1, Sen AK1, Shukla D1, Seth A1.
- Renal failure.Ren Fail.2017 Nov;39(1):130-139. doi: 10.1080/0886022X.2016.1254659. Epub 2016 Nov 13.
- PMID 27841100
Japanese Journal
- 矢島 剛洋,神宮 大輔,庄司 淳 [他]
- 日本呼吸器学会誌 = Annals of the Japanese Respiratory Society 4(2), 176-180, 2015-03-10
- NAID 40020410532
- 2型糖尿病患者の安静時エネルギー消費量に及ぼすDPP-4阻害薬の影響
- 塚原 丘美,岡田 巳紀,立花 詠子,渡邊 源市
- 名古屋栄養科学雑誌 = Nagoya Journal of Nutritional Sciences (1), 63-69, 2015-03
- NAID 120005602080
- A randomized, placebo-controlled, double-blind, phase 3 trial to evaluate the efficacy and safety of anagliptin in drug-naïve patients with type 2 diabetes
- Yang Hae Kyung,Min Kyung Wan,Park Sung Woo,Chung Choon Hee,Park Kyong Soo,Choi Sung Hee,Song Ki-Ho,Kim Doo-Man,Lee Moon-Kyu,Sung Yeon-Ah,Baik Sei Hyun,Kim In Joo,Cha Bong-Soo,Park Jeong Hyun,Ahn Yu Bae,Lee In-Kyu,Yoo Soon Jib,Kim Jaetaek,Park Ie Byung,Park Tae Sun,Yoon Kun-Ho
- Endocrine Journal 62(5), 449-462, 2015
- … Plasma dipeptidyl peptidase (DPP)-4 activity was significantly inhibited after 24 weeks of anagliptin treatment, and >75% and >90% inhibitions were observed during the meal tolerance tests with 100 mg and 200 mg anagliptin, respectively. …
- NAID 130005071798
Related Links
- Ansorge S, Bühling F, Kähne T, et al. (1997). "CD26/dipeptidyl peptidase IV in lymphocyte growth regulation". Adv. Exp. Med. Biol. 421: 127–40. PMID 9330689. Reinhold D, Kähne T, Steinbrecher A, et al. (2003). "The role of ...
- di·pep·ti·dyl pep·ti·dase (dī-pep'ti-dil pep'ti-dās), A hydrolase occurring in a number of forms: dipeptidyl peptidase I, dipeptidyl transferase, cleaving dipeptides from the amino end of polypeptides; dipeptidyl peptidase II, with properties ...
★リンクテーブル★
[★]
[★]
- 英
- dipeptidyl peptidase、dipeptidylpeptidase、DPP
- 関
- ジペプチジルアミノペプチダーゼ
[★]
ジペプチジルアミノペプチダーゼ
- 関
- dipeptidyl peptidase
[★]
ジペプチジルペプチダーゼIV
- 関
- CD26 antigen
[★]
ジペプチジルペプチダーゼI
- 関
- cathepsin C
[★]
ジペプチジルペプチダーゼ4 DPP4
[★]
ジペプチジルペプチダーゼ4阻害薬
[★]
ペプチダーゼ、ペプチド加水分解酵素
- 関
- peptide hydrolase、protease、proteinase、proteolytic enzyme