dipeptidyl-peptidase IV inhibitor

出典: meddic

ジペプチジルペプチダーゼ4阻害薬

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英文文献

  • Dipeptidyl Peptidase IV Inhibitors: A New Paradigm in Type 2 Diabetes Treatment.
  • Janardhan S, Sastry GN1.
  • Current drug targets.Curr Drug Targets.2014 Jun;15(6):600-21.
  • Dipeptidyl peptidase IV (DPP4) is a promising target for the treatment of chronic metabolic type 2 diabetes mellitus (T2D). DPP4 is a highly specific serine protease involved in the regulation and cleavage of two incretin hormones, glucagon-like peptide (GLP-1) and glucose-dependent insulinotropic p
  • PMID 24611684
  • CD26/DPPIV down-regulation in endometrial stromal cell migration in endometriosis.
  • Tan CW1, Lee YH2, Tan HH3, Lau MS3, Choolani M4, Griffith L5, Chan JK6.
  • Fertility and sterility.Fertil Steril.2014 May 10. pii: S0015-0282(14)00312-4. doi: 10.1016/j.fertnstert.2014.04.001. [Epub ahead of print]
  • OBJECTIVE: To test the hypothesis that endometrial stromal cells (ESCs) in endometriosis exhibit increased cell motility under hypoxia.DESIGN: Prospective case-control study.SETTING: University research laboratory.PATIENT(S): Women with endometriosis (n = 18) or benign gynecological disease (n = 19)
  • PMID 24825423
  • Dipeptidyl Petidase-IV Inhibitor (Gemigliptin) Inhibits Tunicamycin-induced Endoplasmic Reticulum Stress, Apoptosis and Inflammation in H9c2 Cardiomyocytes.
  • Hwang HJ1, Jung TW1, Ryu JY1, Hong HC1, Choi HY1, Seo JA1, Kim SG1, Kim NH1, Choi KM1, Choi DS1, Baik SH1, Yoo HJ2.
  • Molecular and cellular endocrinology.Mol Cell Endocrinol.2014 May 7. pii: S0303-7207(14)00135-X. doi: 10.1016/j.mce.2014.04.017. [Epub ahead of print]
  • The direct effects of dipeptidyl peptidase-IV (DPP-IV) inhibitors on endoplasmic reticulum (ER) stress-induced apoptosis and inflammation in cardiomyocytes have not been elucidated. H9c2 cell viability, which was reduced by tunicamycin, was increased after DPP-IV inhibitor gemigliptin treatment. Gem
  • PMID 24813659

和文文献

  • 2型糖尿病患者の安静時エネルギー消費量に及ぼすDPP-4阻害薬の影響
  • 名古屋栄養科学雑誌 = Nagoya Journal of Nutritional Sciences (1), 63-69, 2015-03
  • NAID 120005602080
  • 2P-248 ヒトジペプチジルペプチダーゼIV阻害ジペプチドの網羅的解析(ペプチド工学,一般講演)
  • 2P-247 ヒトジペプチジルペプチダーゼIVを新たな様式で阻害するオリゴペプチド群の発見(ペプチド工学,一般講演)

関連リンク

Sometimes these medicines are combined with other diabetes medicines in one pill. When your body makes incretin, an enzyme called dipeptidyl peptidase-4 ...
Dipeptidyl peptidase 4 inhibitors. A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition.

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★リンクテーブル★
リンク元ジペプチジルペプチダーゼ4阻害薬
関連記事inhibit」「I」「inhibitor」「peptidase」「dipeptidyl peptidase

ジペプチジルペプチダーゼ4阻害薬」

  [★]

dipeptidyl-peptidase IV inhibitor
DPP4阻害薬ジペプチジルペプチダーゼIV阻害薬ジペプチジルペプチダーゼIV阻害剤ジペプチジルペプチダーゼ4阻害剤
ジペプチジルペプチダーゼ4 DPP4糖尿病治療薬シタグリプチン


inhibit」

  [★]

  • v.
  • 抑制する、阻害する、阻止する
abrogateblockdepressdepressiondeterinhibitioninterdictpreventpreventionrepressrepressionrestrainrestraintsuppresssuppression

WordNet   license wordnet

「limit, block, or decrease the action or function of; "inhibit the action of the enzyme"; "inhibit the rate of a chemical reaction"」

PrepTutorEJDIC   license prepejdic

「〈感情・欲望・行動・作用など〉‘を'抑制する / (…しないように)〈人〉‘を'抑制する,妨げる《+『名』+『from』+『名』(do『ing』)》」

WordNet   license wordnet

「control and refrain from showing; of emotions, desires, impulses, or behavior」
bottle up, suppress

WordNet   license wordnet

「limit the range or extent of; "Contact between the young was inhibited by strict social customs"」


I」

  [★]

WordNet   license wordnet

「the 9th letter of the Roman alphabet」
i

PrepTutorEJDIC   license prepejdic

「『私は』私が」

PrepTutorEJDIC   license prepejdic

「iodineの化学記号」


inhibitor」

  [★]

  • n.
blockerdepressantsuppressant

WordNet   license wordnet

「a substance that retards or stops an activity」

PrepTutorEJDIC   license prepejdic

「抑制する人(物) / 化学反応抑制剤」


peptidase」

  [★]

ペプチダーゼペプチド加水分解酵素

peptide hydrolaseproteaseproteinaseproteolytic enzyme


dipeptidyl peptidase」

  [★]

ジペプチジルペプチダーゼ

dipeptidyl aminopeptidasedipeptidylpeptidaseDPP




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