WordNet

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. カルシウムおよびリン酸バランスの調節 regulation of calcium and phosphate balance
2. 高リン血症の原因および治療の概要 overview of the causes and treatment of hyperphosphatemia
3. グルコース-6-リン酸脱水素酵素欠損症の診断および治療 diagnosis and treatment of glucose 6 phosphate dehydrogenase deficiency
4. 慢性腎疾患における高リン血症の治療 treatment of hyperphosphatemia in chronic kidney disease
5. 低リン血症の評価および治療 evaluation and treatment of hypophosphatemia

Jacobson KA1, Paoletta S2, Katritch V3, Wu B4, Gao ZG2, Zhao Q5, Stevens RC3, Kiselev E2.
Molecular pharmacology.Mol Pharmacol.2015 Apr 2. pii: mol.114.095711. [Epub ahead of print]
Eight G protein-coupled P2Y receptor (P2YR) subtypes are important physiological mediators. The human P2YRs are fully activated by: ATP (P2Y2, P2Y11), ADP (P2Y1, P2Y12 and P2Y13), UTP (P2Y2, P2Y4), UDP (P2Y6, P2Y14), and UDP-glucose (P2Y14). Their structural elucidation is progressing rapidly; the X
PMID 25837834

Identification, characterization, and structure analysis of the cyclic di-AMP-binding PII-like signal transduction protein DarA.

Gundlach J1, Dickmanns A2, Schröder-Tittmann K3, Neumann P2, Kaesler J2, Kampf J1, Herzberg C1, Hammer E4, Schwede F5, Kaever V6, Tittmann K3, Stülke J7, Ficner R8.
The Journal of biological chemistry.J Biol Chem.2015 Jan 30;290(5):3069-80. doi: 10.1074/jbc.M114.619619. Epub 2014 Nov 28.
The cyclic dimeric AMP nucleotide c-di-AMP is an essential second messenger in Bacillus subtilis. We have identified the protein DarA as one of the prominent c-di-AMP receptors in B. subtilis. Crystal structure analysis shows that DarA is highly homologous to PII signal transducer proteins. In contr
PMID 25433025

Müller M1, Hopfner KP1, Witte G2.
FEBS letters.FEBS Lett.2015 Jan 2;589(1):45-51. doi: 10.1016/j.febslet.2014.11.022. Epub 2014 Nov 28.
Cyclic-di-AMP (c-di-AMP) is a bacterial secondary messenger involved in various processes, including sensing of DNA-integrity, cell wall metabolism and potassium transport. A number of c-di-AMP receptor proteins have recently been identified in Staphylococcus aureus. One of them - PstA - possesses a
PMID 25435171

On a Salmon (Onchorhynchus keta) Liver RNase, Belonging to RNase T2 Family : Primary Structure and Some Properties

, , [他], , , ,
Bioscience, biotechnology, and biochemistry 69(2), 343-352, 2005-02-23
… The base preferences at the B1 and B2 sites were estimated from the rates of hydrolysis of 16 dinucleoside phosphates to be G>>A>U, C, and G>A>U>C respectively.<BR>In this enzyme, one of the three histidine residues which have been thought to be important for catalysis of RNase Rh, a typical RNase of this family of enzymes, His104 was replaced by tyrosine residue. …
NAID 130000030425

Enzymatic Properties of Double Mutant Enzymes at Asp51 and Trp49 and Asp51 and Tyr57 of RNase Rh from Rhizopus niveus

, , [他],
Bioscience, biotechnology, and biochemistry 61(11), 1913-1918, 1997-11-23
… Mutation of Asp51 of a base-nonspecific RNase, RNase Rh, to Ser, Thr, or Gln makes the enzyme more preferential for the dinucleoside phosphate (XpY) having G and C at the 5'-side (X). …
NAID 110002678843

, , , ,
The Journal of Biochemistry 117(1), 27-33, 1995
… The relative rates of cleavage of dinucleoside phosphates by these two mutant enzymes were comparable to those with RNA as a substrate. …
NAID 130003532388