ジメフリン
- 関
- dimefline hydrochloride
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/12/15 11:08:49」(JST)
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Dimefline
|
Systematic (IUPAC) name |
8-(dimethylaminomethyl)-7-methoxy-3-methyl-2-phenylchromen-4-one |
Clinical data |
AHFS/Drugs.com |
International Drug Names |
Legal status |
?
|
Identifiers |
CAS number |
1165-48-6 |
ATC code |
R07AB08 |
PubChem |
CID 3078 |
ChemSpider |
2969 |
UNII |
9WII5M0DU3 Y |
KEGG |
D07847 Y |
ChEMBL |
CHEMBL519364 |
Chemical data |
Formula |
C20H21NO3 |
Mol. mass |
323.38564 g/mol |
SMILES
- O=C\1c3c(O/C(=C/1C)c2ccccc2)c(c(OC)cc3)CN(C)C
|
InChI
-
InChI=1S/C20H21NO3/c1-13-18(22)15-10-11-17(23-4)16(12-21(2)3)20(15)24-19(13)14-8-6-5-7-9-14/h5-11H,12H2,1-4H3
Key:ZXFQRFXLFWWKLX-UHFFFAOYSA-N
|
Y (what is this?) (verify) |
Dimefline is a respiratory stimulant.
Other respiratory system products (R07)
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Lung surfactants |
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Respiratory stimulants |
- Almitrine
- Amiphenazole
- Bemegride
- Dimefline
- Doxapram
- Etamivan
- Mepixanox
- Nikethamide
- Pentetrazol
- Prethcamide
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5-HT4 receptor agonists |
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Other agents for treating respiratory depression |
- Ivacaftor
- Nitric oxide
- BW373U86
- CX-546
- CX-717
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anat (n, x, l, c)/phys/devp
|
noco (c, p)/cong/tumr, sysi/epon, injr
|
proc, drug (R1/2/3/5/6/7)
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English Journal
- The influence of diuretics on the excretion and metabolism of doping agents--V. Dimefline.
- Delbeke FT1, Debackere M.
- Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.1991;9(1):23-8.
- A sensitive method for the quantitative determination of the respiratory stimulant dimefline in 5 ml urine using capillary gas chromatography with nitrogen specific detection is presented. After the oral administration of a therapeutical amount of 16 mg dimefline to five subjects only 0.26 +/- 0.16%
- PMID 2043718
- Synthesis and quantitative structure-activity relationships of analeptic agents related to dimefline.
- Recanatini M, Valenti P, Da Re P, Giusti P.
- Archiv der Pharmazie.Arch Pharm (Weinheim).1989 May;322(5):257-61.
- Some new dimefline-type derivatives have been synthesized and their pharmacological activity, as well as their distribution coefficients have been determined. The distribution coefficients of a number of previously published analogue compounds have also been measured and the QSAR analysis of the who
- PMID 2569302
- [Mechanism of dimefline].
- Huang Q, Zhang JR.
- Sheng li ke xue jin zhan [Progress in physiology].Sheng Li Ke Xue Jin Zhan.1985 Oct;16(4):353-5.
- PMID 3016888
Japanese Journal
- EEG activation with dimefline hydrochloride
- Kazamatsuri Hajime
- Folia Psychiatrica et Neurologica Japonica 23(1), 15-23, 1969-03
- NAID 40018690063
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- Dimefline is a medicine available in a number of countries worldwide. A list of US medications equivalent to Dimefline is available on the Drugs.com website. ... Drugs.com provides accurate and independent information on more than ...
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