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「nonsteroidal anti-inflammatory (trade name Dolobid) used to treat arthritis and other inflammatory conditions」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/02/02 21:20:13」(JST)

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  • Transthyretin (ATTR) amyloidosis: clinical spectrum, molecular pathogenesis and disease-modifying treatments.
  • Sekijima Y1.
  • Journal of neurology, neurosurgery, and psychiatry.J Neurol Neurosurg Psychiatry.2015 Sep;86(9):1036-43. doi: 10.1136/jnnp-2014-308724. Epub 2015 Jan 20.
  • Transthyretin (ATTR) amyloidosis is a life-threatening, gain-of-toxic-function disease characterised by extracellular deposition of amyloid fibrils composed of transthyretin (TTR). TTR protein destabilised by TTR gene mutation is prone to dissociate from its native tetramer to monomer, and to then m
  • PMID 25604431
  • Synthesis of Diflunisal thiazolidinones as anticancer agents.
  • Şenkardeş S, Özakpınar ÖB, Özsavcı D, Şener A, Çevik Ö, Küçükgüzel ŞG1.
  • Anti-cancer agents in medicinal chemistry.Anticancer Agents Med Chem.2015 Aug 31. [Epub ahead of print]
  • A series of diflunisal 4-thiazolidinones were synthesized. Some selected compounds were determined at one dose towards the full panel of 60 human cancer cell lines by National Cancer Institute. 2',4'-Difluoro-4-hydroxy-N-[4-oxo-2-(thiophen-2-yl)-1,3-thiazolidin-3-yl]biphenyl-3-carboxamide (4a) demon
  • PMID 26320814
  • Easy Access to Supramolecular Gels of the Nonsteroidal Anti-inflammatory Drug Diflunisal: Synthesis, Characterization, and Plausible Biomedical Applications.
  • Parveen R1, Dastidar P2.
  • Chemistry, an Asian journal.Chem Asian J.2015 Aug 6. doi: 10.1002/asia.201500732. [Epub ahead of print]
  • By exploiting salt formation, a new series of primary ammonium monocarboxylate salts of a nonsteroidal anti-inflammatory drug, namely, diflunisal, was synthesized. The majority of the salts thus synthesized turned out to be good gelators of various solvents, including the solvents (e.g., methyl sali
  • PMID 26247886


  • 家族性アミロイドポリニューロパチー : 新規薬物療法(ジフルニサルとタファミジス) (特集 アミロイド関連神経疾患のすべて) -- (封入体筋炎からアルツハイマー病まで)
  • 関島 良樹
  • Brain and nerve : 神経研究の進歩 66(7), 773-781, 2014-07
  • NAID 40020153564
  • 遺伝性アミロイドニューロパチーの多様性と診断・治療のポイント
  • 関島 良樹
  • 臨床神経学 54(12), 953-956, 2014
  • 遺伝性アミロイドポリニューロパチーのほとんどを占める遺伝性ATTRアミロイドーシスは,トランスサイレチン(TTR)遺伝子変異を原因とする常染色体優性の遺伝性疾患である.本症は全身性アミロイドーシスであり,多発ニューロパチー,自律神経障害,心症状,眼症状など多彩な症状が様々な組み合わせで出現する.診断には上記の症状に加え,組織へのアミロイド沈着とTTR遺伝子変異を証明する必要がある.本症に対してはす …
  • NAID 130004921182
  • The inhibitory effect of non-steroidal anti-inflammatory drugs (NSAIDs) on the monophenolase and diphenolase activities of mushroom tyrosinase
  • Sato Kazuomi,Toriyama Masaru
  • International Journal of Molecular Sciences 12(6), 3998-4008, 2011-06-14
  • … The results showed that diflunisal and indomethacin inhibited both monophenolase and diphenolase activity. … For monophenolase activity, the lag time was extended in the presence of diflunisal. … IC(50) values of monophenolase activity were estimated to be 0.112 mM (diflunisal) and 1.78 mM (indomethacin). … Kinetic studies of monophenolase activity revealed that both diflunisal and indomethacin were non-competitive inhibitors. …
  • NAID 120003273777


Diflunisalとは?goo Wikipedia (ウィキペディア) 。出典:Wikipedia(ウィキペディア)フリー百科事典。 Diflunisalとは - goo Wikipedia (ウィキペディア) gooトップ サイトマップ スタートページに設定 RSS ヘルプ メニューへスキップ 本文へ ...
Before taking diflunisal, tell your doctor and pharmacist if you are allergic to diflunisal, aspirin or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), or any other medications. tell your doctor ...


File:Diflunisal-2D-skeletal.png Diflunisal | CAS 22494-42-4 Name: DIFLUNISAL 500 mg755/93 Pill - diflunisal 500 mg _generic_equivalent_to_dolobid_500mg_9173Dolobid (diflunisal) Drug Side Effects




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