- 示差走査型の、示差走査の
WordNet
- relating to or showing a difference; "differential treatment"
- a quality that differentiates between similar things
- involving or containing one or more derivatives; "differential equation"
- the process of translating photographs into a digital form that can be recognized by a computer
- the act of systematically moving a finely focused beam of light or electrons over a surface in order to produce an image of it for analysis or transmission
- distinguishing characteristics (especially in different species of a genus)
PrepTutorEJDIC
- 『差別的な』 / 微分の / 差動の / 〈C〉差別額,運賃差 / 〈U〉微分 / 〈C〉〈U〉(また『differential gear』)差動歯車,差動装置
- (論理学で)種差(ある種が同じ属の他の種と区別される属性);本質的な相違点
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. 産婦人科における超音波検査 ultrasound examination in obstetrics and gynecology
- 2. 骨転移、多発性骨髄腫、およびリンパ腫における完全および切迫病的骨折の評価およびマネージメント evaluation and management of complete and impending pathologic fractures in patients with metastatic bone disease multiple myeloma and lymphoma
- 3. 重症筋無力症の鑑別診断 differential diagnosis of myasthenia gravis
- 4. 固形肝病変：鑑別診断および評価 solid liver lesions differential diagnosis and evaluation
- 5. 肝肥大：鑑別診断および評価 hepatomegaly differential diagnosis and evaluation
English Journal
- Investigation into physical-chemical variables affecting the manufacture and dissolution of wet-milled clarithromycin nanoparticles.
- Shahbazi Niaz M1, Traini D, Young PM, Ghadiri M, Rohanizadeh R.Author information 1Department of Pharmaceutics, School of Pharmacy, Shahid Beheshti University of Medical Sciences , Tehran , Iran .AbstractA critical problem associated with poor water-soluble drugs is their low and variable bioavailability, which is derived from the slow dissolution and erratic absorption. Nano-formulation has been identified as one approach to enhance the rate and extent of drug absorption for compounds that demonstrate limited water solubility. This study aimed to investigate the physico-chemical variables that affect the manufacture, dissolution and consequent bioavailability of wet-milled clarithromycin (CLA) nanoparticles, a macrolide antibiotic. CLA nanoparticles were prepared using wet milling method followed by freeze-drying. Different stabilizer systems, consisting of surfactants and polymers alone or their combinations were studied to determine the optimum conditions for producing nano-sized CLA particles. In vitro characterizations of the CLA nanoparticles were performed using dynamic light scattering, X-ray powder diffraction, differential scanning calorimetry and dissolution efficiency test. Results showed that in general the wet milling process did not modify the crystallinity of the CLA nanoparticles. The poloxamers and polyvinyl alcohol (PVA) stabilizers resulted in nanoparticles with the smallest particle size and best dissolution rates. Furthermore, poloxamers F68 and F127, and PVA stabilizers demonstrated the best performance in increasing dissolution efficacy.
- Pharmaceutical development and technology.Pharm Dev Technol.2014 Dec;19(8):911-21. doi: 10.3109/10837450.2013.840844. Epub 2013 Oct 4.
- A critical problem associated with poor water-soluble drugs is their low and variable bioavailability, which is derived from the slow dissolution and erratic absorption. Nano-formulation has been identified as one approach to enhance the rate and extent of drug absorption for compounds that demonstr
- PMID 24093825
- Solid dispersions of the penta-ethyl ester prodrug of diethylenetriaminepentaacetic acid (DTPA): formulation design and optimization studies.
- Yang YT1, Di Pasqua AJ, Zhang Y, Sueda K, Jay M.Author information 1Division of Molecular Pharmaceutics, Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill , Chapel Hill, NC , USA.AbstractThe penta-ethyl ester prodrug of diethylenetriaminepentaacetic acid (DTPA), which exists as an oily liquid, was incorporated into a solid dispersion for oral administration by the solvent evaporation method using blends of polyvinylpyrrolidone (PVP), Eudragit® RL PO and α-tocopherol. D-optimal mixture design was used to optimize the formulation. Formulations that had a high concentration of both Eudragit® RL PO and α-tocopherol exhibited low water absorption and enhanced stability of the DTPA prodrug. Physicochemical properties of the optimal formulation were evaluated using Fourier transform infrared (FTIR) spectroscopy and differential scanning calorimetry (DSC). In vitro release of the prodrug was evaluated using the USP Type II apparatus dissolution method. DSC studies indicated that the matrix had an amorphous structure, while FTIR spectrometry showed that DTPA penta-ethyl ester and excipients did not react with each other during formation of the solid dispersion. Dissolution testing showed that the optimized solid dispersion exhibited a prolonged release profile, which could potentially result in a sustained delivery of DTPA penta-ethyl to enhance bioavailability. In conclusion, DTPA penta-ethyl ester was successfully incorporated into a solid matrix with high drug loading and improved stability compared to prodrug alone.
- Pharmaceutical development and technology.Pharm Dev Technol.2014 Nov;19(7):806-12. doi: 10.3109/10837450.2013.836216. Epub 2013 Sep 19.
- The penta-ethyl ester prodrug of diethylenetriaminepentaacetic acid (DTPA), which exists as an oily liquid, was incorporated into a solid dispersion for oral administration by the solvent evaporation method using blends of polyvinylpyrrolidone (PVP), Eudragit® RL PO and α-tocopherol. D-optimal mix
- PMID 24047113
- Synthesis and characterization of new derivatives of alginic acid and evaluation of their iron(III)-crosslinked beads as potential controlled release matrices.
- Abulateefeh SR1, Khanfar MA, Al Bakain RZ, Taha MO.Author information 1Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy .AbstractCONTEXT: The excellent gelling and safety profiles of alginic acid combined, however, with drawbacks of its ionotropically crosslinked beads (i.e. their quick release of loaded drugs) prompted us to chemically modify alginic acid.
- Pharmaceutical development and technology.Pharm Dev Technol.2014 Nov;19(7):856-67. doi: 10.3109/10837450.2013.836222. Epub 2013 Sep 13.
- CONTEXT: The excellent gelling and safety profiles of alginic acid combined, however, with drawbacks of its ionotropically crosslinked beads (i.e. their quick release of loaded drugs) prompted us to chemically modify alginic acid.OBJECTIVE: Alginic acid was chemically conjugated with four amines of
- PMID 24032476
Japanese Journal
- Microstructural Evaluation of ZrB<sub>2</sub>/ZrO<sub>2</sub> Ceramic Powders Prepared by Milling-Assisted Magnesiothermic Reduction of Oxide Raw Materials
- KONA Powder and Particle Journal advpub(0), 2017
- NAID 130005123792
- Raman Spectroscopic Investigation of the Superionic Phase Transition in Cs<sub>3</sub>D(SO<sub>4</sub>)<sub>2</sub>
- Journal of the Physical Society of Japan 85(6), 2016-05-09
- NAID 160000001117
- PVDF溶液の滴下・乾燥によるフィルム創成とプリント技術への応用 (特集 3Dプリンタが拓く新しい"ものづくり")
- 砥粒加工学会誌 60(3), 138-141, 2016-03
- NAID 40020755554
Related Links
- Differential scanning calorimetry or DSC is a thermoanalytical technique in which the difference in the amount of heat required to increase the temperature of a sample and reference is measured as a function of temperature. Both the sample ...
- Differential Scanning Calorimetry (DSC) is unsurpassed for understanding the stability of biological systems. DSC directly measures heat changes that occur in biomolecules during controlled increase or decrease in temperature, making it ...
Related Pictures
★リンクテーブル★
| リンク元 | 「示差走査型」「示差走査」 |
| 拡張検索 | 「differential scanning type」「differential scanning calorimetry」 |
| 関連記事 | 「differential」「scanning」 |
「示差走査型」
「示差走査」
「differential scanning type」
「differential scanning calorimetry」
- 関
- DSC
「differential」
- adj.
- 差次的な、差動的な、差動の、示差の、判別の、ディファレンシャル
「scanning」
- n.
- 関
- scan