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Videx, ddl

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/01/10 13:50:40」(JST)

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  • Interference with purinergic signalling: an explanation for the cardiovascular effect of abacavir?
  • Esplugues JV1, De Pablo C, Collado-Díaz V, Hernández C, Orden S, Álvarez Á.
  • AIDS (London, England).AIDS.2016 Jun 1;30(9):1341-51. doi: 10.1097/QAD.0000000000001088.
  • OBJECTIVE: The association of abacavir (ABC), a guanosine analogue, with cardiovascular toxicity is a long-lasting matter of controversy engendered by the lack of a mechanism of action. Clinical data point to an acute mechanism of vascular inflammation. Previous studies have shown that ABC induces l
  • PMID 26990628
  • Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.
  • Vilarinho S1,2, Sari S3, Yilmaz G4, Stiegler AL5, Boggon TJ5,6, Jain D1,2,7, Akyol G4, Dalgic B3, Günel M2,8,9, Lifton RP2,9,10.
  • Hepatology (Baltimore, Md.).Hepatology.2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
  • Despite advances in the diagnosis and management of idiopathic noncirrhotic portal hypertension, its pathogenesis remains elusive. Insight may be gained from study of early-onset familial idiopathic noncirrhotic portal hypertension, in which Mendelian mutations may account for disease. We performed
  • PMID 26874653
  • Prevalence and dynamics of the K65R drug resistance mutation in HIV-1-infected infants exposed to maternal therapy with lamivudine, zidovudine and either nevirapine or nelfinavir in breast milk.
  • Inzaule SC1, Weidle PJ2, Yang C2, Ndiege K3, Hamers RL4, Rinke de Wit TF4, Thomas T2, Zeh C5.
  • The Journal of antimicrobial chemotherapy.J Antimicrob Chemother.2016 Jun;71(6):1619-26. doi: 10.1093/jac/dkw039. Epub 2016 Mar 6.
  • BACKGROUND: K65R is a relatively rare drug resistance mutation (DRM) selected by the NRTIs tenofovir, didanosine, abacavir and stavudine and confers cross-resistance to all NRTIs except zidovudine. Selection by other NRTIs is uncommon.OBJECTIVES: In this study we investigated the frequency of emerge
  • PMID 26953333


  • Noncirrhotic Portal Hypertension Associated with Didanosine : a Case Report and Literature Review
  • Chang Hui-Min,Tsai Hung-Chin,Lee Susan Shin-Jung [他]
  • Japanese Journal of Infectious Diseases 65(1), 61-65, 2012-01
  • NAID 40019139488
  • Simultaneous determination of didanosine and its amino acid prodrug, valdidanosine by hydrophilic interaction chromatography coupled with electrospray ionization tandem mass spectrometry : Application to a pharmacokinetic study in rats
  • YAN Zhongtian,SUN Jin,WANG Jinling,XU Youjun,CHANG Yannan,MENG Ping,ZHU Meng,FU Qiang,SUN Yongbing,HE Zhonggui
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 878(3), 466-470, 2010-02-01
  • NAID 10028032587
  • Determination of abacavir, amprenavir, didanosine, efavirenz, nevirapine, and stavudine concentration in human plasma by MALDI-TOF/TOF
  • NOTARI Stefania,MANCONE Carmine,ALONZI Tonino,TRIPODI Marco,NARCISO Pasquale,ASCENZI Paolo
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 863(2), 249-257, 2008-03-01
  • NAID 10027997438


近年、HIV感染者に発症する非硬変性門脈圧亢進症(Non Cirrhotic Portal Hypertension)と非核酸系逆転写酵素阻害薬Didanosine(商品名:ヴァイデックス・ヴァイデックスEC)との関連が報告されています。 本件に関しては、2010年1月29 ...
didanosine /di·dan·o·sine/ (-dan?o-sēn) 2, an analogue of dideoxyadenosine; an antiretroviral agent used for the treatment of advanced HIV-1 infection and acquired immunodeficiency syndrome, administered orally. di·dan·o·sine (dī-dăn ...






ジデオキシイノシン dideoxyinosine ddI
ヴァイデックス Videx