dichlorobenzyl alcohol

ジクロロベンジルアルコール

WordNet

1. any of a series of volatile hydroxyl compounds that are made from hydrocarbons by distillation
2. a liquor or brew containing alcohol as the active agent; "alcohol (or drink) ruined him" (同)alcoholic drink, alcoholic_beverage, intoxicant, inebriant

PrepTutorEJDIC

1. 『アルコール』,酒精 / 『アルコール飲料』,酒

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/11/07 11:35:12」(JST)

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[Wiki en表示]

2,4-Dichlorobenzyl alcohol
IUPAC name (2,4-Dichlorophenyl)methanol
Other names Dybenal Rapidosept Myacide SP
Identifiers
CAS number	1777-82-8 N
PubChem	15684
ChemSpider	14918 Y
ChEBI	CHEBI:48220 Y
ATC code	R02AA03
Jmol-3D images	Image 1 Image 2
SMILES C1=CC(=C(C=C1Cl)Cl)CO Clc1cc(Cl)ccc1CO
InChI InChI=1S/C7H6Cl2O/c8-6-2-1-5(4-10)7(9)3-6/h1-3,10H,4H2 Y Key: DBHODFSFBXJZNY-UHFFFAOYSA-N Y
Properties
Molecular formula	C7H6Cl2O
Molar mass	177.03 g/mol
Melting point	57-60 °C
Boiling point	150 °C (25 mmHg)
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections. It is a common ingredient in throat lozenges such as Strepsils, Lorsept or Gorpils. A low-pH throat lozenge containing dichlorobenzyl alcohol (1.2 mg) and amylmetacresol (600μg) has been found to deactivate Respiratory syncytial virus and SARS-Cov, but not adenovirus or rhinovirus. A dentifrice containing 10% sodium benzoate and 0.3% dichlorobenzyl alcohol maintains antimicrobial activity for 5–10 minutes after brushing.

References

UpToDate Contents

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• 1. アルコール使用障害の心理社会的治療 psychosocial treatment of alcohol use disorder
• 2. アルコール使用障害：疫学、病因、臨床症状、有害事象、および診断 risky drinking and alcohol use disorder epidemiology pathogenesis clinical manifestations course assessment and diagnosis
• 3. イソプロピルアルコール中毒 isopropyl alcohol poisoning
• 4. 外来における医師監督下のアルコール離脱症状の治療 medically supervised alcohol withdrawal in the ambulatory setting
• 5. 有害なアルコールおよびその他の薬物使用への短期介入 brief intervention for unhealthy alcohol and other drug use

English Journal

• Analysis of 44 pharmaceuticals consumed by elderly using liquid chromatography coupled to tandem mass spectrometry.

• Gómez-Canela C, Sala-Comorera T, Pueyo V, Barata C, Lacorte S.
• Journal of pharmaceutical and biomedical analysis. 2019 May;168()55-63.
• Elderly people represent about the 15% of the total world population and often include a polymedicated age group with an average consumption of 5-10 pills per day. The main pharmaceuticals consumed are antianalgesics, antidiabetics, anti-parkinson compounds, anti-convulsants, drugs to treat constipa
• PMID 30784890

• Spectrum of bactericidal action of amylmetacresol/2,4-dichlorobenzyl alcohol lozenges against oropharyngeal organisms implicated in pharyngitis.

• Matthews D, Atkinson R, Shephard A.
• International journal of general medicine. 2018 ;11()451-456.
• Pharyngitis is commonly caused by a self-limiting upper respiratory tract infection (URTI) and symptoms typically include sore throat. Antibiotics are often inappropriately used for the treatment of pharyngitis, which can contribute to antimicrobial resistance, therefore non-antibiotic treatments wh
• PMID 30568479

• Effectiveness of amylmetacresol and 2,4-dichlorobenzyl alcohol throat lozenges in patients with acute sore throat due to upper respiratory tract infection: a systematic review protocol.

• Tan TW, Chen BC, Tan HL, Chang CM.
• JBI database of systematic reviews and implementation reports. 2017 04;15(4)862-872.
• This review aims to determine the best available evidence related to the effectiveness of amylmetacresol and 2,4-dichlorobenzyl alcohol throat lozenges in patients with acute sore throat due to upper respiratory tract infection (URTI). The objective is to examine the analgesic properties of amylmeta
• PMID 28398972

Japanese Journal

• Effects of the β_2-Agonist Clenbuterol on β_1- and β_2-Adrenoceptor mRNA Expressions of Rat Skeletal and Left Ventricle Muscles

• Sato Shogo,Nomura Sachiko,Kawano Fuuun [他],TANIHATA Jun,TACHIYASHIKI Kaoru,IMAIZUMI Kazuhiko
• Journal of pharmacological sciences 107(4), 393-400, 2008-08-20
• … The β2-agonist clenbuterol [4-amino-α(t-butyl-amino)methyl-3,5-dichlorobenzyl alcohol] is used as a non-steroidal anabolic drug for sports doping. …
• NAID 10024321814

• β_2-Agonist Clenbuterol Induced Changes in the Distribution of White Blood Cells in Rats

• Shirato Ken,Tanihata Jun,Motohashi Norio [他],TACHIYASHIKI Kaoru,TOMODA Akio,IMAIZUMI Kazuhiko
• Journal of pharmacological sciences 104(2), 146-152, 2007-06-20
• … Clenbuterol [CLE: 4-amino-α(t-butyl-amino)methyl-3,5-dichlorobenzyl alcohol] is well known as a potent β2-adrenergic agonist and non-steroidal anabolic drug, and thus it is generally used for sports doping and asthma therapy. …
• NAID 10024314331

• シクロデキストリンとの複合体形成によるアラルキルアルコール類の製剤特性の向上

• 上釜 兼人 [他],王 克敏,平山 文俊,小田切 優樹,柴田 元雄,大谷 淑郎,山田 義次,杉山 幸雄
• 藥學雜誌 102(12), 1141-1149, 1982-12-25
• … In the presence of CyDs, an increase in inhibitory-zone diameter of aralkylalcohols including 2,4-dichlorobenzyl alcohol (DCBA) was observed by cup-plate method and no reduction of their antimicrobial activities was also found. …
• NAID 110003650277

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リンク元	「ジクロロベンジルアルコール」
関連記事	「alcohol」

「ジクロロベンジルアルコール」

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英

dichlorobenzyl alcohol

「alcohol」

　　[★] アルコール

関

ethanol