WordNet
- a substance that exerts some force or effect
- a businessman who buys or sells for another in exchange for a commission (同)factor, broker
- any agent or representative of a federal agency or bureau (同)federal agent
- a representative who acts on behalf of other persons or organizations
- an active and efficient cause; capable of producing a certain effect; "their research uncovered new disease agents"
- how long something has existed; "it was replaced because of its age"
- a time of life (usually defined in years) at which some particular qualification or power arises; "she was now of school age"; "tall for his eld" (同)eld
- begin to seem older; get older; "The death of his wife caused him to age fast"
- make older; "The death of his child aged him tremendously"
- concerned with diagnosis; used for furthering diagnosis; "a diagnostic reading test"
- characteristic or indicative of a disease; "a diagnostic sign of yellow fever"; "a rash symptomatic of scarlet fever"; "symptomatic of insanity"; "a rise in crime symptomatic of social breakdown" (同)symptomatic
PrepTutorEJDIC
- 『代理人』;周旋人 / 働き(作用)を起こすもの;作用物,薬剤 / (政府機関,特にFBI,CIAなどの)部員,機関員
- 〈U〉(一般に)『年齢』,寿命;〈C〉(個々の)『年齢』,年 / 〈U〉成年(おとなとしての資格・権利を得る年齢;通例18または21歳) / 〈U〉『老齢』;《集合的に》老人たち / 〈U〉(人生の)『一時期』;〈C〉世代(generation) / 〈U〉〈C〉《しばしばA-》(歴史上の)『時代』 / 〈C〉《話》長い間 / 年をとる,ふける;〈物が〉古くなる / 〈年〉'を'とらせる;〈物〉'を'古びさせる
- 診断の,診断のために役立つ
UpToDate Contents
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- 1. QRS幅の広い頻脈の診断のアプローチ approach to the diagnosis of wide qrs complex tachycardias
- 2. 糖尿病でない成人における低血糖症：診断的アプローチ hypoglycemia in adults without diabetes mellitus diagnostic approach
- 3. 成人における市中肺炎に対する診断的アプローチ diagnostic approach to community acquired pneumonia in adults
- 4. 性器潰瘍患者へのアプローチ approach to the patient with genital ulcers
- 5. 前立腺癌の危険因子 risk factors for prostate cancer
English Journal
- Fluorescence turn-on sensing of protein based on mannose functionalized perylene bisimides and its fluorescence imaging.
- Wang KR1, An HW2, Rong RX2, Cao ZR2, Li XL3.Author information 1Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding, PR China; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, Baoding, PR China. Electronic address: kerangwang@hbu.edu.cn.2Department of Immunology, School of Basic Medical Science, Hebei University, Baoding, PR China.3Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding, PR China; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, Baoding, PR China. Electronic address: lixl@hbu.cn.AbstractA new water-soluble glycocluster based on perylene bisimides PBI-12-Man has been designed and synthesized, and its specific and selective binding property with Concanavalin A (Con A) has been investigated by fluorescence spectroscopy and circular dichroism (CD) spectroscopy, which showed strong binding affinity for Con A with the binding constant of 8.2×10(5)M(-1) for monomeric mannose unit, two orders of magnitude higher than the corresponding monosaccharide ligand. Most interestingly, a fluorescence enhancement of PBI-12-Man was observed upon binding with Con A because of deaggregation of the self-assembly of PBI-12-Man induced by carbohydrate-protein interaction, and the further study of the fluorescence enhancement with macrophage cells showed that PBI-12-Man as a biocompatible agent had fluorescence imaging of the surface mannose receptor of the cells. Such fluorescence turn-on sensing of protein based on carbohydrate-protein interactions would facilitate the development of new protein-specific fluorescent probe for diagnosis and molecular imaging under live cell conditions.
- Biosensors & bioelectronics.Biosens Bioelectron.2014 Aug 15;58:27-32. doi: 10.1016/j.bios.2014.02.038. Epub 2014 Feb 22.
- A new water-soluble glycocluster based on perylene bisimides PBI-12-Man has been designed and synthesized, and its specific and selective binding property with Concanavalin A (Con A) has been investigated by fluorescence spectroscopy and circular dichroism (CD) spectroscopy, which showed strong bind
- PMID 24607619
- Influence of different iodinated contrast media on the induction of DNA double-strand breaks after in vitro X-ray irradiation.
- Deinzer CK1, Danova D, Kleb B, Klose KJ, Heverhagen JT.Author information 1Department of Diagnostic and Interventional Radiology, Philipps University, Marburg, Germany.AbstractThe objective of this work was to examine differences in DNA double-strand break induction in peripheral blood lymphocytes after in vitro X-ray irradiation between iodinated contrast agents. Four different iodinated X-ray contrast agents - three of them with two different iodine concentrations - and mannitol (negative control; concentration of 150 mg mannitol per ml blood) were pipetted into blood samples so that there was a concentration of 0, 7.5 or 15 mg of iodine per ml blood in the samples. Negative controls without contrast medium (0 mg of iodine per ml blood) were also processed for every irradiation dose. The tubes were exposed to 0, 20 or 500 mGy in vitro X-ray irradiation. After that, the lymphocytes were separated by using density-gradient centrifugation. Fluorescence microscopy was applied to determine the average number of γH2AX-foci per lymphocyte in the presence or absence of different contrast media or mannitol. Differences in the number of γH2AX-foci were statistically analysed by one-way ANOVA and post-hoc Tukey's honestly significant difference test. Iodinated contrast agents led to a statistically significant increase in DNA double-strand breaks after in vitro irradiation. This effect increased statistically significant with rising radiation dose and appeared independent of the contrast agent used (iopromid, iodixanol, iomeprol, iopamidol). A statistically significant difference in DNA damage between the different tested contrast agents was not found. Therefore, the increase in DNA double-strand breaks depends solely on the amount of iodine applied. For evaluation of clinical consequences, our findings could be tested in further animal studies. Copyright © 2014 John Wiley & Sons, Ltd.
- Contrast media & molecular imaging.Contrast Media Mol Imaging.2014 Jul;9(4):259-67. doi: 10.1002/cmmi.1567.
- The objective of this work was to examine differences in DNA double-strand break induction in peripheral blood lymphocytes after in vitro X-ray irradiation between iodinated contrast agents. Four different iodinated X-ray contrast agents - three of them with two different iodine concentrations - and
- PMID 24706609
- Rapid identification of differentially virulent genotypes of Paenibacillus larvae, the causative organism of American foulbrood of honey bees, by whole cell MALDI-TOF mass spectrometry.
- Schäfer MO1, Genersch E2, Fünfhaus A2, Poppinga L2, Formella N1, Bettin B3, Karger A4.Author information 1Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Infectology, Südufer 10, 17493 Greifswald-Insel Riems, Germany.2Institute for Bee Research, Friedrich-Engels-Str. 32, 16540 Hohen Neuendorf, Germany.3Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Molecular Biology, Südufer 10, 17493 Greifswald-Insel Riems, Germany.4Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Molecular Biology, Südufer 10, 17493 Greifswald-Insel Riems, Germany. Electronic address: axel.karger@fli.bund.de.AbstractInfection with Paenibacillus larvae, the etiological agent of American foulbrood, is lethal for honey bee larvae and may lead to loss of the entire colony. Of the four known ERIC-genotypes of P. larvae, ERIC I and II are most frequently observed and differ significantly in virulence. The course of the disease on the larval level is more accelerated after infection with genotype II strains allowing nurse bees to remove diseased larvae more efficiently before capping. For this reason the lead clinical symptom, conversion of capped larvae into 'ropy mass', is less frequently found than after infection with ERIC I strains bearing the risk of false negative diagnosis. In this study, the potential of matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF MS) for the discrimination of P. larvae genotypes ERIC I and II was explored on the basis of a comprehensive set of isolates. Using commercial software and a reference database constructed from field and type strains, ERIC I and II genotypes of all field isolates could be unambiguously identified on basis of mass spectra. Statistical analysis showed that the genotype is the main determinant for the spectral phenotype and MS-based ERIC-type determination is robust against sample selection. Furthermore, analysis of samples from Canada and New Zealand showed that distribution of ERIC II is not restricted to Europe as previously assumed. We suggest adding ERIC I and II genotype isolates as type-specific reference spectra for use in routine diagnostics.
- Veterinary microbiology.Vet Microbiol.2014 Jun 4;170(3-4):291-7. doi: 10.1016/j.vetmic.2014.02.006. Epub 2014 Feb 15.
- Infection with Paenibacillus larvae, the etiological agent of American foulbrood, is lethal for honey bee larvae and may lead to loss of the entire colony. Of the four known ERIC-genotypes of P. larvae, ERIC I and II are most frequently observed and differ significantly in virulence. The course of t
- PMID 24613082
Japanese Journal
- 放射線治療とレドックスイメージング
- 松本 謙一郎
- 薬学雑誌. 乙号 135(5), 719-724, 2015
- … Magnetic resonance-based redox imaging techniques, which can estimate tissue redox status non-invasively, have been developed not only for diagnostic information but also for estimating the efficacy of treatment. …
- NAID 130005066934
- Clear Visualization of Extravasation on Angiography Using Carbon Dioxide in a Case of Hepatocellular Carcinoma Rupture with Unclear Visualization Using Iodine Contrast Agent
- Ochi Hironori,Hirooka Masashi,Koizumi Yohei,Tada Fujimasa,Watanabe Takao,Tokumoto Yoshio,Tanaka Hiroaki,Mochizuki Teruhito,Abe Masanori,Hiasa Yoichi
- Internal Medicine 54(4), 407-410, 2015
- … Extravasation of the HCC tumor was not detected on angiography with iodine contrast agent; … This modality be more effective and safe than angiography with iodine contrast agent for assessing potential ruptured HCC lesions. …
- NAID 130004903047
- 右傍胸骨部に生じた神経内分泌分化を示す皮膚原発アポクリン腺癌の1例
- 飯島 茂子,神崎 美玲,真壁 郁,長倉 成憲,菅野 雅人,坂田 晃子,野口 雅之
- Skin Cancer 29(2), 165-170, 2015
- 80歳，男性。2002年より右胸部にざ瘡様の皮疹が出現したが放置。2012年8月初診時，右傍胸骨部に20×19×5 mm大の広基性紅色腫瘤があり，表面はびらんを伴い易出血性であった。全身検索にて転移なし。汗腺系悪性腫瘍，無色素性悪性黒色腫などを疑い，広範切除，全層植皮術を行った。病理組織学的に，ルーペ像では，真皮内に主座を置く左右非対称性，隆起性病変であった。腫瘍細胞の構築は，充実性胞巣状，索状， …
- NAID 130004836582
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★リンクテーブル★
| リンク元 | 「診断用薬」 |
| 関連記事 | 「agent」「diagnostic」「age」 |
「診断用薬」
- 英
- diagnostic agent
- 関
- 診断薬
「agent」
- n.
- 代行者、代理人。代理業者
- 政府職員、官吏
- ある後位をする人、ある作用をするもの。動員、動力因、作用因。(文法)動作主。科学的変化を起こさせるもの、薬品、～剤。病原体
- 関
- agonist、agonistic、attorney、delegate、drug、etiologic agent、fomes、fomites、mediator、pathogen、pathogenic、pharmaceutical preparation、vector、vehicle
「diagnostic」
- adj.
- 診断上の、診断の、特徴的な
- 関
- assessment、characteristic、characteristically、diagnose、diagnoses、diagnosis、diagnostically、discriminatory、distinct、distinctive、distinctively、pathognomonic
「age」
- n.
- 年齢、歳
- v.
- 加齢する、熟成する