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1. 肺悪性腫瘍の病理 pathology of lung malignancies
2. 不整脈原性右室心筋症：発症機序と遺伝 arrhythmogenic right ventricular cardiomyopathy pathogenesis and genetics
3. ダリエ病 darier disease
4. 皮膚剥脱症候群 peeling skin syndrome
5. 天疱瘡の病因、臨床症状、および診断 pathogenesis clinical manifestations and diagnosis of pemphigus

English Journal

A desmoplakin point mutation with enhanced keratin association ameliorates pemphigus vulgaris autoantibody-mediated loss of cell cohesion.

Dehner C1, Rötzer V1, Waschke J2, Spindler V3.
The American journal of pathology.Am J Pathol.2014 Sep;184(9):2528-36. doi: 10.1016/j.ajpath.2014.05.016. Epub 2014 Jul 8.
Desmoplakin (DP) serves to anchor intermediate filaments in desmosomal complexes. Recent data suggest that a specific DP point mutation (S2849G) exhibits increased keratin filament association and fosters Ca(2+) insensitivity of desmosomes in keratinocytes, presumably by rendering DP inaccessible fo
PMID 25010392

Titin and desmosomal genes in the natural history of arrhythmogenic right ventricular cardiomyopathy.

Brun F1, Barnes CV2, Sinagra G3, Slavov D2, Barbati G3, Zhu X2, Graw SL2, Spezzacatene A1, Pinamonti B3, Merlo M1, Salcedo EE2, Sauer WH2, Taylor MR2, Mestroni L2; on behalf of the Familial Cardiomyopathy Registry.
Journal of medical genetics.J Med Genet.2014 Aug 25. pii: jmedgenet-2014-102591. doi: 10.1136/jmedgenet-2014-102591. [Epub ahead of print]
BACKGROUND: Genotype-phenotype correlations are poorly characterised in arrhythmogenic right ventricular cardiomyopathy (ARVC). We investigated whether carriers of rare variants in desmosomal genes (DC) and titin gene (TTN) display different phenotypes and clinical outcomes compared with non-carrier
PMID 25157032

Desmocollin‑2 affects the adhesive strength and cytoskeletal arrangement in esophageal squamous cell carcinoma cells.

Fang WK1, Liao LD2, Zeng FM1, Zhang PX1, Wu JY1, Shen J2, Xu LY3, Li EM1.
Molecular medicine reports.Mol Med Rep.2014 Aug 12. doi: 10.3892/mmr.2014.2485. [Epub ahead of print]
Desmocollin‑2 (DSC2), a transmembrane glycoprotein belonging to the desmosomal cadherin family, has been found to be differentially expressed in several types of cancer and to be involved in tumor progression. The tumor metastasis suppressing property of DSC2 in esophageal squamous cell carcinoma
PMID 25119898

Heterogeneous and abnormal localization of desmosomal proteins in oral intraepithelial neoplasms

Aizawa Sohichi,Ochiai Takanaga,Ara Toshiaki,Yamada Haruki,Hasegawa Hiromasa
Journal of Oral Science 56(3), 209-214, 2014
To study the relationship between the biological and morphological characteristics of oral intraepithelial neoplasms (OINs), we examined the localization of desmosome-related proteins. Twenty-seven ca …
NAID 130004691130

Oral Candidiasis: A Histopathological, Ultrastructural and Immunohistochemical Study

Abe Yotaro
International Journal of Oral-Medical Sciences 12(3), 171-182, 2014
… Ultrastructually, Candidal hyphe internalized into the epithelial cytoplasmic vacuole resembling endocytosis.Destruction of desmosomal cell junction and deficit of tonofilament was also observed at the tip of the hypha. …
NAID 130003395899