WordNet

(physiology) the process whereby nerves can retard or prevent the functioning of an organ or part; "the inhibition of the heart by the vagus nerve"
(psychology) the conscious exclusion of unacceptable thoughts or desires (同)suppression
the quality of being inhibited
coming down or downward

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1. 線維筋痛症の病因 pathogenesis of fibromyalgia
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Metamizol, a non-opioid analgesic, acts via endocannabinoids in the PAG-RVM axis during inflammation in rats.

Escobar W, Ramirez K, Avila C, Limongi R, Vanegas H, Vazquez E.SourceCentro de Biofísica y Bioquímica, Instituto Venezolano de Investigaciones Científicas (IVIC), Apartado 20632, Caracas, 1020-A, Venezuela.
European journal of pain (London, England).Eur J Pain.2012 May;16(5):676-89. doi: 10.1002/j.1532-2149.2011.00057.x. Epub 2011 Dec 19.
The most commonly used drugs against pain act by inhibiting the cyclooxygenases (COXs). Metamizol (dipyrone) inhibits the COXs and is widely used in Europe and Latin America as a non-opioid analgesic. One target of metamizol and other non-opioid analgesics is the periaqueductal grey matter (PAG), wh
PMID 22337336

The combined predictive capacity of rat models of algogen-induced and neuropathic hypersensitivity to clinically used analgesics varies with nociceptive endpoint and consideration of locomotor function.

Munro G, Storm A, Hansen MK, Dyhr H, Marcher L, Erichsen HK, Sheykhzade M.SourceNeuroSearch A/S, 93 Pederstrupvej, DK-2750 Ballerup, Denmark.
Pharmacology, biochemistry, and behavior.Pharmacol Biochem Behav.2012 May;101(3):465-78. Epub 2012 Feb 16.
Different neurobiological mechanism(s) might contribute to evoked and non-evoked pains and to limited translational drug discovery efforts. Other variables including the pain model and sensory testing method used, dose/route/preadministration time of compound(s), lack of adverse effect profiling and
PMID 22366217

堀田晴美
自律神経 56(1), 46-53, 2019
<p>ローラー（somaplane）を使った皮膚への軽い触刺激には，麻酔ラットの膀胱の排尿収縮を抑制する作用がある．その刺激は，過活動膀胱のセルフケアに臨床応用されている．一方，陰部神経や脛骨神経の電気刺激が膀胱機能を調節するneuromodulationの基礎及び臨床研究が近年精力的に行われている．これらの作用は，中枢神経内における排尿反射の興奮性伝達が，分節性の体性求心性入力によっ …
NAID 130007634995

Enhancement of pain inhibition by working memory with anodal transcranial direct current stimulation of the left dorsolateral prefrontal cortex

The effects of opposite-directional static contraction of the muscles of the right upper extremity on the ipsilateral right soleus H-reflex

Shiratani Tomoko,Arai Mitsuo,Kuruma Hironobu,Masumoto Kazue
Journal of Bodywork and Movement Therapies 21(3), 528-533, 2017-07
… The induction of neurophysiological descending effects for inhibition requires consideration of the force direction. …
NAID 120006627273