English Journal

Bostic HE, Smith MD, Poloukhtine AA, Popik VV, Best MD.SourceDepartment of Chemistry, The University of Tennessee, Knoxville, TN, 37996, USA. mdbest@utk.edu.
Chemical communications (Cambridge, England).Chem Commun (Camb).2012 Feb 1;48(10):1431-3. Epub 2011 Oct 3.
Copper-free click chemistry was employed to derivatize membrane bilayers. This approach uses an azido-lipid conjugate presented on liposomes, which can be labeled in bioorthogonal fashion via cyclooctyne-tagged reagents. An immobilization-based approach using streptavidin-coated microplates was expl
PMID 21963550

A MALDI-TOF MS method for the simultaneous and quantitative analysis of neutral and sialylated glycans of CHO-expressed glycoproteins.

Tep S, Hincapie M, Hancock WS.SourceBiogen Idec, 14 Cambridge Center, Cambridge, MA 02142, United States.
Carbohydrate research.Carbohydr Res.2012 Jan 10;347(1):121-9. Epub 2011 Oct 20.
The development of a MALDI-TOF MS method for the quantitative analysis of the glycosylation of CHO-expressed biotherapeutic glycoproteins shall be presented. The method utilizes a well-established chemistry, reductive amination of glycans, to derivatize glycans with either a light analog ((12)C(7) a
PMID 22138464

Fast and Selective Modification of Thiol Proteins/Peptides by N-(Phenylseleno)phthalimide.

Wang Z, Zhang Y, Zhang H, Harrington PB, Chen H.SourceCenter for Intelligent Chemical Instrumentation, Department of Chemistry and Biochemistry, Ohio University, Athens, OH, 45701, USA.
Journal of the American Society for Mass Spectrometry.J Am Soc Mass Spectrom.2012 Jan 6. [Epub ahead of print]
We previously reported that selenamide reagents such as ebselen and N-(phenylseleno)phthalimide (NPSP) can be used to selectively derivatize thiols for mass spectrometric analysis, and the introduced selenium tags are useful as they could survive or removed with collision-induced dissociation (CID).
PMID 22223263

Japanese Journal

Design, Synthesis and Antiviral Activity of 2-(3-Amino-4-piperazinylphenyl)chromone Derivatives

Kim Mi Kyoung,Yoon Hyunjun,Barnard Dale Lynn [他],Chong Youhoon
Chemical and Pharmaceutical Bulletin 61(4), 486-488, 2013
… In the course of our ongoing efforts to optimize the antiviral activity of the chromone derivatives, we have been attempting to derivatize the chromone scaffold via introduction of various substituents. …
NAID 130003360752

野澤由利子,新井好史,川嶋朗,原田健一
天然有機化合物討論会講演要旨集 (48), 517-522, 2006-09-15
… 3) derivatize a desired compound with L- or D-FDLA and analyze by LC/MS. 4) compare the elution order with the prospective one and determine the absolute configuration of the asymmetric carbon. …
NAID 110006682707

六鹿元雄,河村葉子,棚元憲一
日本食品化学学会誌 10(3), 138-144, 2003-12-12
… PET samples were dissolved in trifluoroacetic acid in the presence of 2,4-dinitrophenylhydrazine to derivatize formaldehyde and acetaldehyde to their dinitrophenylhydrazone derivatives. …
NAID 110007367275