WordNet

reason or establish by induction
cause to arise; "induce a crisis" (同)bring_on
produce electric current by electrostatic or magnetic processes (同)induct
cause to do; cause to act in a specified manner; "The ads induced me to buy a VCR"; "My children finally got me to buy a computer"; "My wife made me buy a new sofa" (同)stimulate, cause, have, get, make
cause to occur rapidly; "the infection precipitated a high fever and allergic reactions" (同)stimulate, rush, hasten
brought about or caused; not spontaneous; "a case of steroid-induced weakness"
a loss of polarity or polarization (同)depolarisation

PrepTutorEJDIC

〈人〉‘に'『勧めて』(…)『させる』 / …‘を'『引き起こす』,もたらす(cause) / 〈電気〉‘を'誘導する / …‘を'帰納する

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1. 心筋の興奮性、不整脈の発症機序、抗不整脈薬の作用機序cardiac excitability mechanisms of arrhythmia and action of antiarrhythmic drugs [show details]
… sodium channel in depolarized tissues. They tend to bind in the inactivated state (which is induced by depolarization) and dissociate from the sodium channel more rapidly than other class I drugs. As a result …
2. 低カリウム性周期性四肢麻痺hypokalemic periodic paralysis [show details]
…channel in muscle fibers from patients with hypokalemic PP does not prevent insulin-induced membrane depolarization . This is also consistent with a secondary channelopathy . The mechanism of paralysis …
3. 小児における高カリウム血症のマネージメントmanagement of hyperkalemia in children [show details]
…also be initiated as quickly as possible. Calcium directly antagonizes the hyperkalemia-induced depolarization of the resting cardiac membrane. Calcium therapy results in decreased membrane excitability…
4. ランバートイートン筋無力症候群：臨床的特徴および診断lambert eaton myasthenic syndrome clinical features and diagnosis [show details]
…Acetylcholine release was increased by increasing calcium concentrations but not by potassium-induced membrane depolarization. The identification of normal presynaptic ACh content further supported the concept that …
5. 小児のミオパチー患者や筋生検を受ける小児患者に行う麻酔anesthesia for children with myopathy and for children who undergo muscle biopsy [show details]
…result of muscle contraction in the presence of an unstable sarcolemma. The succinylcholine induced depolarization of muscle membranes is thought to cause membrane damage in susceptible patients, but the …

English Journal

A role for the Ca2+-dependent tyrosine kinase Pyk2 in tonic depolarization-induced vascular smooth muscle contraction.

Mills RD1, Mita M, Walsh MP.
Journal of muscle research and cell motility.J Muscle Res Cell Motil.2015 Jul 7. [Epub ahead of print]
Depolarization of the plasma membrane is a key mechanism of activation of contraction of vascular smooth muscle. This is commonly achieved in isolated, de-endothelialized vascular smooth muscle strips by increasing extracellular [K+] (replacing Na+ by K+) and leads to a rapid phasic contraction foll
PMID 26150074

Altered ROS production, NF-κB activation and interleukin-6 gene expression induced by electrical stimulation in dystrophic mdx skeletal muscle cells.

Henríquez-Olguín C1, Altamirano F2, Valladares D3, López JR4, Allen PD4, Jaimovich E5.
Biochimica et biophysica acta.Biochim Biophys Acta.2015 Jul;1852(7):1410-9. doi: 10.1016/j.bbadis.2015.03.012. Epub 2015 Apr 7.
Duchenne muscular dystrophy is a fatal X-linked genetic disease, caused by mutations in the dystrophin gene, which cause functional loss of this protein. This pathology is associated with an increased production of reactive oxygen (ROS) and nitrogen species. The aim of this work was to study the alt
PMID 25857619

Synaptic plasticity in the auditory system: a review.

Friauf E1, Fischer AU, Fuhr MF.
Cell and tissue research.Cell Tissue Res.2015 Jul;361(1):177-213. doi: 10.1007/s00441-015-2176-x. Epub 2015 Apr 21.
Synaptic transmission via chemical synapses is dynamic, i.e., the strength of postsynaptic responses may change considerably in response to repeated synaptic activation. Synaptic strength is increased during facilitation, augmentation and potentiation, whereas a decrease in synaptic strength is char
PMID 25896885

Japanese Journal

新たなてんかん治療標的分子synaptic vesicle protein 2A（SV2A）の機能解析

徳留健太郎,清水佐紀,芹川忠夫,大野行弘
日本薬理学雑誌 152(6), 275-280, 2018
<p>てんかんは反復性の発作を主症状とする慢性の神経疾患であり，その罹患率は人口の1％にのぼる．近年，新たなてんかん治療の標的分子としてシナプス小胞タンパク質SV2A（synaptic vesicle protein 2A）が注目されている．SV2Aは神経伝達物質の活動電位依存性シナプス分泌を促進的に調節する機能がある．これまでの報告において，①<i>Sv2a</i& …
NAID 130007528441

Neurotransmitter release: vacuolar ATPase V0 sector c-subunits in possible gene or cell therapies for Parkinson's, Alzheimer's, and psychiatric diseases

Higashida Haruhiro,Yokoyama Shigeru,Tsuji Chiharu,Muramatsu Shin-ichi
The journal of physiological sciences 67(1), 11-17, 2017-01
… Adeno-associated viral vector-mediated gene transfer of ATP6V0C into the caudate putamen enhanced the depolarization-induced overflow of endogenous DA in Parkinson-model mice. …
NAID 120005971993

Synaptic vesicle glycoprotein 2A (SV2A) regulates kindling epileptogenesis via GABAergic neurotransmission

Tokudome Kentaro,Okumura Takahiro,Shimizu Saki,Mashimo Tomoji,Takizawa Akiko,Serikawa Tadao,Terada Ryo,Ishihara Shizuka,Kunisawa Naofumi,Sasa Masashi,Ohno Yukihiro
Scientific Reports (6), 2016-06-06
… Neurochemical studies revealed that the Sv2a[L174Q] mutation specifically reduced depolarization-induced GABA, but not glutamate, release in the hippocampus without affecting basal release or the SV2A expression level in GABAergic neurons. …
NAID 120006349333